STRINGSTRING
Atg2b Atg2b Gria1 Gria1 Pum1 Pum1 Adrm1 Adrm1 Pik3r4 Pik3r4 Ern1 Ern1 Nop56 Nop56 Psmb2 Psmb2 Opa1 Opa1 Atp2a2 Atp2a2 Mcu Mcu Nrbf2 Nrbf2 Pik3r2-2 Pik3r2-2 Akt2 Akt2 Psma3 Psma3 Kcnc1 Kcnc1 Rbpj Rbpj Wipi2 Wipi2 Psmb6 Psmb6 ENSMAUP00000022689 ENSMAUP00000022689 Itpr3 Itpr3 Nfya Nfya ENSMAUP00000022538 ENSMAUP00000022538 Psma6 Psma6 Pik3ca Pik3ca Psmd4 Psmd4 Grin1 Grin1 Psmc1 Psmc1 Ppif Ppif Kcnd3 Kcnd3 Grin2c Grin2c Tbp Tbp Psma5 Psma5 Psmb3 Psmb3 Ulk2 Ulk2 Psmd11 Psmd11 ENSMAUP00000021279 ENSMAUP00000021279 Psmd8 Psmd8 Bean1 Bean1 Slc25a4 Slc25a4 Rora Rora Reln Reln Sp1 Sp1 ENSMAUP00000020392 ENSMAUP00000020392 Map3k5 Map3k5 Afg3l2 Afg3l2 ENSMAUP00000019352 ENSMAUP00000019352 Psmb5 Psmb5 Psma8 Psma8 Mapk9 Mapk9 Mapk10 Mapk10 Itpr1 Itpr1 Pik3r2 Pik3r2 Sptbn2 Sptbn2 Cyct Cyct Ryr1 Ryr1 Atxn1l Atxn1l Psmd1 Psmd1 Akt3 Akt3 Sem1 Sem1 Atg2a Atg2a Psmb1 Psmb1 Kat5 Kat5 Atg101 Atg101 Gria2 Gria2 Mtor Mtor ENSMAUP00000016290 ENSMAUP00000016290 Twnk Twnk Grin2d Grin2d Plcb1 Plcb1 Psmb4 Psmb4 Oma1 Oma1 Osbpl2 Osbpl2 Tbpl2 Tbpl2 Psmd2 Psmd2 Psmd3 Psmd3 Psmd14 Psmd14 Myod1 Myod1 Gtf2b Gtf2b Psmd12 Psmd12 Xbp1 Xbp1 Prkcb Prkcb ENSMAUP00000012891 ENSMAUP00000012891 Akt1 Akt1 Itpr2 Itpr2 Atg14 Atg14 Psmc5 Psmc5 Plcb4 Plcb4 ENSMAUP00000012115 ENSMAUP00000012115 Slc25a31 Slc25a31 ENSMAUP00000011880 ENSMAUP00000011880 Psmd6 Psmd6 Psmd7 Psmd7 Atxn2l Atxn2l Kcnc3 Kcnc3 Psmd9 Psmd9 Atp2a1 Atp2a1 Atxn1 Atxn1 Wipi1 Wipi1 Psma7 Psma7 Psma4 Psma4 Pdyn Pdyn Atg13 Atg13 Slc1a6 Slc1a6 Kcnc2 Kcnc2 Grin2b Grin2b Vdac3 Vdac3 Fgf12 Fgf12 Psma2 Psma2 Psmb7 Psmb7 Grin2a Grin2a Gria3 Gria3 Psmc4 Psmc4 Pik3c3 Pik3c3 Dab1 Dab1 Ambra1 Ambra1 Prkca Prkca Psma1 Psma1 Atxn10 Atxn10 Trpc7 Trpc7 Atxn2 Atxn2 Pik3r1 Pik3r1 Lyl1 Lyl1 Afg3l1 Afg3l1 Psmc2 Psmc2 Psmc6 Psmc6 Grin3b Grin3b Kcnc4 Kcnc4 Psmc3 Psmc3 CUNH7orf31 CUNH7orf31 LOC106021303 LOC106021303 Pum2 Pum2 Vldlr Vldlr LOC101842058 LOC101842058 Traf2 Traf2 Rb1cc1 Rb1cc1 LOC101841110 LOC101841110 Cic Cic Prkcg Prkcg ENSMAUP00000001870 ENSMAUP00000001870 Pik3cd Pik3cd Psmd13 Psmd13 Rb1cc1-2 Rb1cc1-2 LOC106021192 LOC106021192 ENSMAUP00000002714 ENSMAUP00000002714 LOC101831400 LOC101831400 Tbpl1 Tbpl1 Grm1 Grm1 Atxn3 Atxn3 Ulk1 Ulk1 Atp2a3 Atp2a3 Mapk8 Mapk8 Becn1 Becn1 Plcb2 Plcb2 ENSMAUP00000004913 ENSMAUP00000004913 Fgf14 Fgf14 Vdac2 Vdac2 Pik3cb Pik3cb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Atg2bAutophagy-related protein 2 homolog B. (1137 aa)
Gria1Glutamate receptor 1 isoform X2. (907 aa)
Pum1Pumilio homolog 1 isoform X4. (1187 aa)
Adrm1Proteasomal ubiquitin receptor ADRM1. (407 aa)
Pik3r4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
Ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (373 aa)
Nop56Nucleolar protein 56. (590 aa)
Psmb2Proteasome subunit beta. (201 aa)
Opa1Dynamin-like 120 kDa protein, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (276 aa)
Atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (966 aa)
McuCalcium uniporter protein, mitochondrial isoform X1. (350 aa)
Nrbf2Nuclear receptor-binding factor 2 isoform X1. (287 aa)
Pik3r2-2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Psma3Proteasome subunit alpha type. (180 aa)
Kcnc1Potassium voltage-gated channel subfamily C member 1 isoform X2; Belongs to the potassium channel family. (585 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Wipi2WD repeat domain phosphoinositide-interacting protein 2. (445 aa)
Psmb6Proteasome subunit beta. (238 aa)
ENSMAUP00000022689annotation not available (268 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
NfyaNuclear transcription factor Y subunit alpha isoform X1. (347 aa)
ENSMAUP00000022538annotation not available (95 aa)
Psma6Proteasome subunit alpha type. (246 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
Grin1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
PpifPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
Kcnd3Potassium voltage-gated channel subfamily D member 3 isoform X1; Belongs to the potassium channel family. (655 aa)
Grin2cGlutamate receptor ionotropic, NMDA 2C isoform X1. (1237 aa)
TbpTATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase [...] (300 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmb3Proteasome subunit beta. (202 aa)
Ulk2Serine/threonine-protein kinase ULK2. (1023 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
ENSMAUP00000021279annotation not available (98 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
Bean1Protein BEAN1. (275 aa)
Slc25a4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
RoraNuclear receptor ROR-alpha isoform X1. (523 aa)
RelnReelin isoform X2. (3258 aa)
Sp1Transcription factor Sp1 isoform X1. (786 aa)
ENSMAUP00000020392annotation not available (68 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1381 aa)
Afg3l2AFG3 like matrix AAA peptidase subunit 2. (176 aa)
ENSMAUP00000019352annotation not available (763 aa)
Psmb5Proteasome subunit beta. (256 aa)
Psma8Proteasome subunit alpha type. (237 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
Pik3r2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa)
Sptbn2Spectrin beta chain; Belongs to the spectrin family. (2388 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Ryr1LOW QUALITY PROTEIN: ryanodine receptor 1. (4094 aa)
Atxn1lAtaxin-1-like. (688 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Sem126S proteasome complex subunit SEM1. (70 aa)
Atg2aAutophagy-related protein 2 homolog A isoform X5. (1917 aa)
Psmb1Proteasome subunit beta. (240 aa)
Kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (515 aa)
Atg101Autophagy-related protein 101. (218 aa)
Gria2Glutamate receptor 2 isoform X3. (883 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ENSMAUP00000016290annotation not available (246 aa)
TwnkTwinkle protein, mitochondrial. (586 aa)
Grin2dGlutamate receptor ionotropic, NMDA 2D. (1251 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Oma1Metalloendopeptidase OMA1, mitochondrial. (451 aa)
Osbpl2Oxysterol-binding protein; Belongs to the OSBP family. (483 aa)
Tbpl2TATA box-binding protein-like protein 2 isoform X1. (353 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Myod1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (318 aa)
Gtf2bTranscription initiation factor IIB. (316 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Xbp1X-box-binding protein 1. (210 aa)
PrkcbProtein kinase C beta. (554 aa)
ENSMAUP00000012891annotation not available (590 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa)
Atg14Beclin 1-associated autophagy-related key regulator. (462 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
ENSMAUP00000012115annotation not available (87 aa)
Slc25a31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
ENSMAUP00000011880annotation not available (232 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Atxn2lAtaxin-2-like protein isoform X2. (1093 aa)
Kcnc3Potassium voltage-gated channel subfamily C member 3 isoform X3; Belongs to the potassium channel family. (767 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (980 aa)
Atxn1Ataxin-1. (790 aa)
Wipi1WD repeat domain phosphoinositide-interacting protein 1. (446 aa)
Psma7Proteasome subunit alpha type. (145 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Pdynproenkephalin-B. (249 aa)
Atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (516 aa)
Slc1a6Amino acid transporter. (562 aa)
Kcnc2Potassium voltage-gated channel subfamily C member 2. (405 aa)
Grin2bGlutamate receptor ionotropic, NMDA 2B. (1483 aa)
Vdac3Voltage-dependent anion-selective channel protein 3 isoform X2. (283 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
Psma2Proteasome subunit alpha type. (245 aa)
Psmb7Proteasome subunit beta. (277 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
Gria3Glutamate receptor 3 isoform X2. (895 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (898 aa)
Dab1Disabled homolog 1 isoform X5. (555 aa)
Ambra1Activating molecule in BECN1-regulated autophagy protein 1. (1195 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Psma1Proteasome subunit alpha type. (206 aa)
Atxn10Ataxin-10. (445 aa)
Trpc7Short transient receptor potential channel 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
Atxn2Ataxin-2 isoform X2. (660 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Lyl1Voltage-dependent P/Q-type calcium channel subunit alpha-1A. (2248 aa)
Afg3l1AFG3-like protein 1. (455 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Grin3bGlutamate receptor ionotropic, NMDA 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (999 aa)
Kcnc4Potassium voltage-gated channel subfamily C member 4 isoform X2; Belongs to the potassium channel family. (625 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
CUNH7orf31Uncharacterized protein C7orf31 homolog isoform X1. (589 aa)
LOC106021303Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
Pum2Pumilio homolog 2 isoform X1. (1066 aa)
VldlrVery low-density lipoprotein receptor isoform X1. (510 aa)
LOC101842058Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
Rb1cc1RB1 inducible coiled-coil 1. (164 aa)
LOC101841110LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like. (321 aa)
CicProtein capicua homolog isoform X4. (2499 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
ENSMAUP00000001870annotation not available (99 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Rb1cc1-2RB1-inducible coiled-coil protein 1 isoform X2. (227 aa)
LOC106021192ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (248 aa)
ENSMAUP00000002714annotation not available (58 aa)
LOC101831400Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa)
Tbpl1TATA box-binding protein-like protein 1. (186 aa)
Grm1Metabotropic glutamate receptor 1. (829 aa)
Atxn3Ataxin-3 isoform X4. (291 aa)
Ulk1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1040 aa)
Atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1038 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Becn1Beclin-1 isoform X1. (456 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ENSMAUP00000004913annotation not available (165 aa)
Fgf14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
Vdac2Voltage-dependent anion-selective channel protein 2. (295 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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