STRINGSTRING
Hdac5 Hdac5 H2bc1 H2bc1 ENSMAUP00000001718 ENSMAUP00000001718 Gng14 Gng14 Fosb Fosb Ppp1cc Ppp1cc Gnai1 Gnai1 Pkia Pkia Nmd3 Nmd3 Gnao1 Gnao1 Gng8 Gng8 Sos1 Sos1 Creb3 Creb3 Calm1 Calm1 Hdac6 Hdac6 LOC110341725 LOC110341725 Hdac4 Hdac4 Bdnf Bdnf Gng2 Gng2 Shc4 Shc4 Camk4 Camk4 Creb3l3 Creb3l3 Sos2 Sos2 LOC106022112 LOC106022112 Cep152 Cep152 LOC101834284 LOC101834284 Csde1 Csde1 ENSMAUP00000014414 ENSMAUP00000014414 LOC101824849 LOC101824849 ENSMAUP00000014706 ENSMAUP00000014706 H3f3b H3f3b Atf6b Atf6b Ntrk2 Ntrk2 Calml4 Calml4 Macroh2a2 Macroh2a2 Ppp1cb Ppp1cb Grin2d Grin2d Raf1 Raf1 Adora2a Adora2a Slc29a2 Slc29a2 Gng12 Gng12 Ppp1ca Ppp1ca Braf Braf Ddc Ddc Macroh2a1 Macroh2a1 Crh Crh ENSMAUP00000018058 ENSMAUP00000018058 Gng10 Gng10 Grb2 Grb2 Mapk1 Mapk1 Kras Kras LOC106022591 LOC106022591 Maob Maob LOC101840877 LOC101840877 LOC101844254 LOC101844254 LOC101843996 LOC101843996 LOC101839356 LOC101839356 LOC101841418 LOC101841418 LOC101841682 LOC101841682 LOC106022595 LOC106022595 LOC101841148 LOC101841148 ENSMAUP00000019710 ENSMAUP00000019710 Maoa Maoa H1f1 H1f1 Slc18a1 Slc18a1 H2bc3 H2bc3 Creb1 Creb1 H1f2 H1f2 LOC101828345 LOC101828345 H1f6 H1f6 ENSMAUP00000020205 ENSMAUP00000020205 ENSMAUP00000020273 ENSMAUP00000020273 H1f4 H1f4 ENSMAUP00000020297 ENSMAUP00000020297 ENSMAUP00000020303 ENSMAUP00000020303 LOC101830217 LOC101830217 Atf2 Atf2 H1f3 H1f3 ENSMAUP00000020353 ENSMAUP00000020353 ENSMAUP00000020431 ENSMAUP00000020431 Gm4356 Gm4356 Th Th Gnas Gnas Npy Npy Gngt2 Gngt2 Calm2 Calm2 Grin2c Grin2c ENSMAUP00000021947 ENSMAUP00000021947 Hat1 Hat1 H3f3a H3f3a Grin1 Grin1 Shc1 Shc1 Nras Nras Hras Hras Hdac7 Hdac7 Hdac2 Hdac2 Gng11 Gng11 Hdac1 Hdac1 Gnai2 Gnai2 Gng3 Gng3 ENSMAUP00000012091 ENSMAUP00000012091 Mapk3 Mapk3 LOC101825376 LOC101825376 Atf4 Atf4 LOC110340247 LOC110340247 ENSMAUP00000011068 ENSMAUP00000011068 Gnb4 Gnb4 Hdac3 Hdac3 Calm3 Calm3 Adcy5 Adcy5 Drd1 Drd1 LOC101829406 LOC101829406 Map2k1 Map2k1 Slc29a3 Slc29a3 Gng4 Gng4 Drd2 Drd2 Pdyn Pdyn LOC101829234 LOC101829234 Gnb2 Gnb2 LOC101828432 LOC101828432 H2aw H2aw H2bu2 H2bu2 Shc3 Shc3 Grin2b Grin2b Gng13 Gng13 ENSMAUP00000008766 ENSMAUP00000008766 ENSMAUP00000008754 ENSMAUP00000008754 Araf Araf ENSMAUP00000008488 ENSMAUP00000008488 Gng7 Gng7 H2ax H2ax Gnb3 Gnb3 Slc18a2 Slc18a2 Grin2a Grin2a Creb5 Creb5 Gnb5 Gnb5 Creb3l2 Creb3l2 Gnai3 Gnai3 ENSMAUP00000006097 ENSMAUP00000006097 Grin3b Grin3b Shc2 Shc2 LOC101826865 LOC101826865 LOC101825928 LOC101825928 Slc29a1 Slc29a1 Hdac8 Hdac8 LOC101843803 LOC101843803 Hdac9 Hdac9 LOC101843531 LOC101843531 H2bc18 H2bc18 Hdac11 Hdac11 Prkaca Prkaca H2az2 H2az2 Calml3 Calml3 Ppp1r1b Ppp1r1b Eras Eras Camkk2 Camkk2 Creb3l1 Creb3l1 Prkacb Prkacb Abcf2 Abcf2 Hdac10 Hdac10 H2aj H2aj Adora2b Adora2b Gngt1 Gngt1 H2ac1 H2ac1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1118 aa)
H2bc1Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSMAUP00000001718annotation not available (115 aa)
Gng14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
FosbProtein fosB isoform X1. (338 aa)
Ppp1ccProtein phosphatase 1 catalytic subunit gamma. (216 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
PkiacAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
Nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa)
Gnao1Guanine nucleotide-binding protein G(O) subunit alpha isoform X2. (354 aa)
Gng8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
Sos1Son of sevenless homolog 1. (1319 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (386 aa)
Calm1Calmodulin 1. (149 aa)
Hdac6Histone deacetylase 6 isoform X3. (1134 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1081 aa)
BdnfBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (287 aa)
Gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
Shc4SHC adaptor protein 4. (204 aa)
Camk4Calcium/calmodulin-dependent protein kinase type IV isoform X1; Belongs to the protein kinase superfamily. (466 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (475 aa)
Sos2Son of sevenless homolog 2 isoform X1. (1308 aa)
LOC106022112Histone H2A; Belongs to the histone H2A family. (64 aa)
Cep152Centrosomal protein of 152 kDa. (1691 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
ENSMAUP00000014414annotation not available (313 aa)
LOC101824849Histone H2A; Belongs to the histone H2A family. (121 aa)
ENSMAUP00000014706annotation not available (414 aa)
H3f3bHistone H3; Belongs to the histone H3 family. (136 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta isoform X2. (73 aa)
Ntrk2Tyrosine-protein kinase receptor. (823 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Macroh2a2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
Ppp1cbProtein phosphatase 1 catalytic subunit beta. (298 aa)
Grin2dGlutamate receptor ionotropic, NMDA 2D. (1251 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
Adora2aAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
Slc29a2Equilibrative nucleoside transporter 2. (458 aa)
Gng12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (50 aa)
Ppp1caSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
BrafSerine/threonine-protein kinase B-raf. (710 aa)
Ddcaromatic-L-amino-acid decarboxylase. (480 aa)
Macroh2a1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
CrhCorticoliberin. (187 aa)
ENSMAUP00000018058annotation not available (76 aa)
Gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
KrasGTPase KRas isoform X3. (189 aa)
LOC106022591Histone H4. (103 aa)
MaobAmine oxidase. (522 aa)
LOC101840877Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101844254Histone H2B type 1. (126 aa)
LOC101843996Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC101839356Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101841418Histone H2A type 1-E. (130 aa)
LOC101841682Histone H2B type 1. (126 aa)
LOC106022595Histone H4. (103 aa)
LOC101841148Histone H2A type 1-E. (130 aa)
ENSMAUP00000019710annotation not available (70 aa)
MaoaAmine oxidase. (525 aa)
H1f1Histone H1.1. (213 aa)
Slc18a1Chromaffin granule amine transporter. (521 aa)
H2bc3Histone H2B; Belongs to the histone H2B family. (126 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
H1f2Histone H1.2. (211 aa)
LOC101828345Histone H3-like. (136 aa)
H1f6Histone H1t. (208 aa)
ENSMAUP00000020205annotation not available (103 aa)
ENSMAUP00000020273annotation not available (126 aa)
H1f4Histone H1.4. (219 aa)
ENSMAUP00000020297annotation not available (117 aa)
ENSMAUP00000020303annotation not available (136 aa)
LOC101830217Histone H2B type 1. (126 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
H1f3Histone H1.3. (220 aa)
ENSMAUP00000020353annotation not available (103 aa)
ENSMAUP00000020431annotation not available (107 aa)
Gm4356Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ThTyrosine 3-monooxygenase. (498 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
NpyPro-neuropeptide Y. (97 aa)
Gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Calm2Calmodulin 2. (149 aa)
Grin2cGlutamate receptor ionotropic, NMDA 2C isoform X1. (1237 aa)
ENSMAUP00000021947annotation not available (57 aa)
Hat1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
H3f3aHistone H3.3. (136 aa)
Grin1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
Shc1SHC-transforming protein 1 isoform X1. (579 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
Hdac7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (957 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Gng11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
Hdac1Histone deacetylase 1. (303 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSMAUP00000012091annotation not available (86 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
LOC101825376LOW QUALITY PROTEIN: uncharacterized protein LOC101825376. (136 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
LOC110340247LOW QUALITY PROTEIN: histone H3, embryonic-like. (135 aa)
ENSMAUP00000011068annotation not available (105 aa)
Gnb4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
Hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
Adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
LOC101829406Histone H4. (103 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
Slc29a3Equilibrative nucleoside transporter 3. (475 aa)
Gng4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Drd2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (444 aa)
Pdynproenkephalin-B. (249 aa)
LOC101829234Histone H2B; Belongs to the histone H2B family. (126 aa)
Gnb2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (382 aa)
LOC101828432Histone H3; Belongs to the histone H3 family. (136 aa)
H2awHistone H2A; Belongs to the histone H2A family. (130 aa)
H2bu2Histone H2B; Belongs to the histone H2B family. (126 aa)
Shc3SHC-transforming protein 3. (595 aa)
Grin2bGlutamate receptor ionotropic, NMDA 2B. (1483 aa)
Gng13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
ENSMAUP00000008766annotation not available (97 aa)
ENSMAUP00000008754annotation not available (103 aa)
ArafSerine/threonine-protein kinase A-Raf isoform X2. (604 aa)
ENSMAUP00000008488annotation not available (71 aa)
Gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
H2axHistone H2A; Belongs to the histone H2A family. (143 aa)
Gnb3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
Slc18a2Synaptic vesicular amine transporter. (447 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa)
Gnb5Guanine nucleotide-binding protein subunit beta-5. (388 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X2. (520 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
ENSMAUP00000006097annotation not available (76 aa)
Grin3bGlutamate receptor ionotropic, NMDA 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (999 aa)
Shc2SHC-transforming protein 2. (573 aa)
LOC101826865Cyclic AMP-responsive element-binding protein 3-like protein 4. (213 aa)
LOC101825928Histone H4. (103 aa)
Slc29a1Equilibrative nucleoside transporter 1 isoform X1. (457 aa)
Hdac8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (390 aa)
LOC101843803Histone H2B; Belongs to the histone H2B family. (126 aa)
Hdac9Histone deacetylase 9 isoform X13. (114 aa)
LOC101843531Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2bc18Histone H2B; Belongs to the histone H2B family. (126 aa)
Hdac11Histone deacetylase 11. (352 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
H2az2Histone H2A; Belongs to the histone H2A family. (128 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Ppp1r1bProtein phosphatase 1 regulatory subunit 1B. (223 aa)
ErasGTPase ERas. (228 aa)
Camkk2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (579 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
Abcf2ATP-binding cassette sub-family F member 2. (625 aa)
Hdac10Histone deacetylase 10 isoform X2. (675 aa)
H2ajHistone H2A; Belongs to the histone H2A family. (126 aa)
Adora2bAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
Gngt1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
H2ac1Histone H2A; Belongs to the histone H2A family. (130 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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