STRINGSTRING
Plcb2 Plcb2 Il12a Il12a Aadacl2fm2 Aadacl2fm2 Aadacl2 Aadacl2 Cygb Cygb Ighm Ighm Faslg Faslg Prkca Prkca Lama4 Lama4 Fas Fas Il10 Il10 LOC101823068 LOC101823068 LOC110339291 LOC110339291 Apol6 Apol6 Myd88 Myd88 Nppa Nppa Mb Mb Icam1 Icam1 ENSMAUP00000004122 ENSMAUP00000004122 Aadacl2fm1 Aadacl2fm1 Vcam1 Vcam1 Kng1 Kng1 ENSMAUP00000002714 ENSMAUP00000002714 Prkcg Prkcg Hbb-y Hbb-y LOC101840881 LOC101840881 Hbb-bh1 Hbb-bh1 Ido1 Ido1 Hba-x Hba-x Il12b Il12b Apol8 Apol8 F2rl1 F2rl1 Plcb4 Plcb4 Ngb Ngb Prkcb Prkcb Il18 Il18 Ifng Ifng Tnf Tnf Plcb1 Plcb1 Thop1 Thop1 Sele Sele Tlr9 Tlr9 Il1b Il1b Il6 Il6 Apoa1 Apoa1 Aadac Aadac Ido2 Ido2 Hp Hp HBB HBB ENSMAUP00000024144 ENSMAUP00000024144
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
Il12aInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (206 aa)
Aadacl2fm2Arylacetamide deacetylase-like 2. (401 aa)
Aadacl2Arylacetamide deacetylase-like 2. (401 aa)
CygbCytoglobin; Belongs to the globin family. (195 aa)
IghmIg mu chain C region. (454 aa)
FaslgTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Lama4Laminin subunit alpha-4. (1610 aa)
FasTumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa)
Il10Interleukin-10 isoform X1. (178 aa)
LOC101823068Apolipoprotein L2-like. (312 aa)
LOC110339291Apolipoprotein L3-like. (186 aa)
Apol6Apolipoprotein L6. (240 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
NppaNatriuretic peptides A. (153 aa)
MbMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
Icam1Intercellular adhesion molecule 1 isoform X2. (516 aa)
ENSMAUP00000004122annotation not available (116 aa)
Aadacl2fm1LOW QUALITY PROTEIN: arylacetamide deacetylase-like 2. (257 aa)
Vcam1Vascular cell adhesion protein 1. (736 aa)
Kng1Kininogen-1 isoform X1. (614 aa)
ENSMAUP00000002714annotation not available (58 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
Hbb-yHemoglobin subunit epsilon-Y2; Belongs to the globin family. (147 aa)
LOC101840881Hemoglobin subunit beta-Y; This is a minor early embryonic beta chain; Belongs to the globin family. (147 aa)
Hbb-bh1Hemoglobin subunit beta-Z-like; Belongs to the globin family. (147 aa)
Ido1Indoleamine 2,3-dioxygenase 1 isoform X1. (397 aa)
Hba-xHemoglobin subunit zeta; Belongs to the globin family. (142 aa)
Il12bInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (327 aa)
Apol8Apolipoprotein L2. (344 aa)
F2rl1Proteinase-activated receptor 2. (398 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
NgbNeuroglobin; Belongs to the globin family. (151 aa)
PrkcbProtein kinase C beta. (554 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (197 aa)
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (174 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Thop1Thimet oligopeptidase. (688 aa)
SeleLOW QUALITY PROTEIN: E-selectin. (555 aa)
Tlr9Toll-like receptor 9. (1030 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Il6Interleukin-6. (212 aa)
Apoa1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (264 aa)
AadacArylacetamide deacetylase. (397 aa)
Ido2Indoleamine 2,3-dioxygenase 2 isoform X1. (405 aa)
HpHaptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] (346 aa)
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (152 aa)
ENSMAUP00000024144annotation not available (159 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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