STRINGSTRING
Nid2 Nid2 Itgb2 Itgb2 Csf3 Csf3 Thbs1 Thbs1 Ccl2 Ccl2 HBB HBB Thbs3 Thbs3 Cd40lg Cd40lg Lrp1b Lrp1b LOC101822612 LOC101822612 ENSMAUP00000020463 ENSMAUP00000020463 Cd81 Cd81 Sdc2 Sdc2 Il6 Il6 Il1b Il1b Tlr9 Tlr9 Cr1l Cr1l Tlr4 Tlr4 Sele Sele ENSMAUP00000017208 ENSMAUP00000017208 Selp Selp Ackr1 Ackr1 ENSMAUP00000014933 ENSMAUP00000014933 Tnf Tnf Klrb1f Klrb1f Ifng Ifng Incenp Incenp Il18 Il18 Ccl12 Ccl12 Met Met Gypc Gypc Ngb Ngb Cd40 Cd40 Thbs2 Thbs2 Pecam1 Pecam1 Hba-x Hba-x Itgal Itgal Comp Comp LOC101824481 LOC101824481 Myd88 Myd88 Tgfb2 Tgfb2 Thbs4 Thbs4 Lrp1 Lrp1 ENSMAUP00000007592 ENSMAUP00000007592 Il10 Il10 Clec12a Clec12a Sdc1 Sdc1 Hgf Hgf Cygb Cygb Il12a Il12a Mb Mb Icam1 Icam1 Tgfb3 Tgfb3 Vcam1 Vcam1 Tgfb1 Tgfb1 Klrk1 Klrk1 Nid1 Nid1 Tlr2 Tlr2 Hbb-y Hbb-y Cd36 Cd36 LOC101840881 LOC101840881 Hbb-bh1 Hbb-bh1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nid2Nidogen-2. (1282 aa)
Itgb2Integrin beta. (304 aa)
Csf3Granulocyte colony-stimulating factor. (208 aa)
Thbs1Thrombospondin-1 isoform X1. (1171 aa)
Ccl2C-C motif chemokine. (143 aa)
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (152 aa)
Thbs3Thrombospondin-3. (956 aa)
Cd40lgCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
Lrp1bLow-density lipoprotein receptor-related protein 1B. (3244 aa)
LOC101822612Killer cell lectin-like receptor subfamily B member 1B allele C. (273 aa)
ENSMAUP00000020463annotation not available (168 aa)
Cd81Tetraspanin. (236 aa)
Sdc2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
Il6Interleukin-6. (212 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Tlr9Toll-like receptor 9. (1030 aa)
Cr1lComplement component receptor 1-like protein. (401 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
SeleLOW QUALITY PROTEIN: E-selectin. (555 aa)
ENSMAUP00000017208annotation not available (174 aa)
SelpP-selectin isoform X1. (771 aa)
Ackr1Atypical chemokine receptor 1. (335 aa)
ENSMAUP00000014933annotation not available (261 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
Klrb1fKiller cell lectin-like receptor subfamily B member 1F. (189 aa)
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (174 aa)
IncenpInner centromere protein isoform X4. (817 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (197 aa)
Ccl12C-C motif chemokine. (105 aa)
MetHepatocyte growth factor receptor. (1382 aa)
Gypcglycophorin-C isoform X1. (72 aa)
NgbNeuroglobin; Belongs to the globin family. (151 aa)
Cd40Tumor necrosis factor receptor superfamily member 5 isoform X2. (290 aa)
Thbs2Thrombospondin-2. (1143 aa)
Pecam1Platelet and endothelial cell adhesion molecule 1. (532 aa)
Hba-xHemoglobin subunit zeta; Belongs to the globin family. (142 aa)
ItgalIntegrin alpha-L; Belongs to the integrin alpha chain family. (1159 aa)
CompCartilage oligomeric matrix protein. (755 aa)
LOC101824481Killer cell lectin-like receptor subfamily B member 1F. (176 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
Thbs4Thrombospondin-4. (867 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (4017 aa)
ENSMAUP00000007592annotation not available (68 aa)
Il10Interleukin-10 isoform X1. (178 aa)
Clec12aC-type lectin domain family 12 member A. (232 aa)
Sdc1Syndecan-1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. (309 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
CygbCytoglobin; Belongs to the globin family. (195 aa)
Il12aInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (206 aa)
MbMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
Icam1Intercellular adhesion molecule 1 isoform X2. (516 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Vcam1Vascular cell adhesion protein 1. (736 aa)
Tgfb1Transforming growth factor beta-1. (286 aa)
Klrk1NKG2-D type II integral membrane protein isoform X2. (234 aa)
Nid1Nidogen-1. (1246 aa)
Tlr2Toll-like receptor. (784 aa)
Hbb-yHemoglobin subunit epsilon-Y2; Belongs to the globin family. (147 aa)
Cd36Platelet glycoprotein 4; Multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor- ligand complexes. The depende [...] (472 aa)
LOC101840881Hemoglobin subunit beta-Y; This is a minor early embryonic beta chain; Belongs to the globin family. (147 aa)
Hbb-bh1Hemoglobin subunit beta-Z-like; Belongs to the globin family. (147 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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