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| | Crebbp | CREB-binding protein. (2433 aa) |
| | Mapk8 | Mitogen-activated protein kinase. (427 aa) |
| | LOC101842510 | Signal transducer and activator of transcription 5A. (228 aa) |
| | Nfkbia | NF-kappa-B inhibitor alpha. (314 aa) |
| | Tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | Mmp9 | Matrix metalloproteinase-9. (718 aa) |
| | Traf6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa) |
| | Ywhab | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (110 aa) |
| | Casp3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (246 aa) |
| | LOC101824534 | Interferon alpha-12-like. (183 aa) |
| | Ep300 | Histone acetyltransferase p300 isoform X3. (2417 aa) |
| | E2f2 | Transcription factor E2F2 isoform X1. (449 aa) |
| | Eras | GTPase ERas. (228 aa) |
| | Tgfb1 | Transforming growth factor beta-1. (286 aa) |
| | Map2k7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (520 aa) |
| | Ccne1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | Creb3l1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa) |
| | Irak1 | Interleukin-1 receptor-associated kinase 1 isoform X2. (747 aa) |
| | LOC101831400 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa) |
| | ENSMAUP00000002714 | annotation not available (58 aa) |
| | Dhdh | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa) |
| | Tgfbr2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | Ywhaz | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (212 aa) |
| | LOC101835654 | Signal transducer and activator of transcription. (228 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ENSMAUP00000001870 | annotation not available (99 aa) |
| | Prkcg | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa) |
| | Tlr2 | Toll-like receptor. (784 aa) |
| | Cdkn1a | Cyclin-dependent kinase inhibitor 1. (163 aa) |
| | E2f1 | Transcription factor E2F1. (383 aa) |
| | Tmed7 | Transmembrane emp24 domain-containing protein 7. (225 aa) |
| | LOC101842058 | Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | Egr3 | Early growth response protein 3 isoform X2. (387 aa) |
| | Tbk1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | Stat6 | Signal transducer and activator of transcription. (746 aa) |
| | D1Pas1 | Putative ATP-dependent RNA helicase Pl10 isoform X2; Belongs to the DEAD box helicase family. (665 aa) |
| | Sos1 | Son of sevenless homolog 1. (1319 aa) |
| | Mapk11 | Mitogen-activated protein kinase. (355 aa) |
| | Smad3 | Mothers against decapentaplegic homolog. (425 aa) |
| | Tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (395 aa) |
| | Irf3 | Interferon regulatory factor 3 isoform X1. (420 aa) |
| | Mapk12 | Mitogen-activated protein kinase. (367 aa) |
| | Tab1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (254 aa) |
| | Birc5 | Baculoviral IAP repeat-containing protein 5. (142 aa) |
| | Ddx3x | ATP-dependent RNA helicase DDX3X; Belongs to the DEAD box helicase family. (662 aa) |
| | Ddx58 | Putative ATP-dependent RNA helicase DDX58. (908 aa) |
| | Traf3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa) |
| | Tlr3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | Pik3r2-2 | Phosphoinositide-3-kinase regulatory subunit 2. (71 aa) |
| | Egr2 | E3 SUMO-protein ligase EGR2 isoform X1. (468 aa) |
| | Map2k6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa) |
| | Creb3l3 | Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (475 aa) |
| | Rb1 | Retinoblastoma-associated protein. (906 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Stat4 | Signal transducer and activator of transcription. (748 aa) |
| | Map2k3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | Hras | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) |
| | Nras | NRAS proto-oncogene, GTPase. (98 aa) |
| | Irf7 | Interferon regulatory factor 7 isoform X1. (394 aa) |
| | Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | E2f3 | Transcription factor E2F3 isoform X1. (460 aa) |
| | Fos | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa) |
| | Cdk2 | Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa) |
| | ENSMAUP00000021279 | annotation not available (98 aa) |
| | Ptk2b | Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | Casp8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa) |
| | Atf2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa) |
| | Ticam1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (733 aa) |
| | Ccna2 | Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa) |
| | Creb1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | Nfkb1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa) |
| | Ticam2 | TIR domain-containing adapter molecule 2. (233 aa) |
| | Tyk2 | Tyrosine-protein kinase. (1190 aa) |
| | Fadd | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | Il6 | Interleukin-6. (212 aa) |
| | Kras | GTPase KRas isoform X3. (189 aa) |
| | Chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) |
| | Mapk9 | Mitogen-activated protein kinase. (423 aa) |
| | Mapk13 | Mitogen-activated protein kinase. (366 aa) |
| | LOC101823400 | 14-3-3 protein theta pseudogene. (252 aa) |
| | Mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa) |
| | Tlr4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa) |
| | Ywhaq | 14-3-3 protein theta; Belongs to the 14-3-3 family. (278 aa) |
| | Mapk10 | Mitogen-activated protein kinase 10. (252 aa) |
| | Grb2 | Growth factor receptor-bound protein 2. (217 aa) |
| | Pik3r2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa) |
| | Map3k7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa) |
| | Cyct | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Braf | Serine/threonine-protein kinase B-raf. (710 aa) |
| | Tirap | Toll/interleukin-1 receptor domain-containing adapter protein isoform X2. (245 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (360 aa) |
| | Irak4 | Interleukin-1 receptor-associated kinase 4. (461 aa) |
| | Raf1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | Rela | Transcription factor p65 isoform X1. (260 aa) |
| | Bax | Apoptosis regulator BAX isoform X1. (192 aa) |
| | Stat1 | Signal transducer and activator of transcription. (749 aa) |
| | Ikbkb | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa) |
| | Atf6b | Cyclic AMP-dependent transcription factor ATF-6 beta isoform X2. (73 aa) |
| | ENSMAUP00000015128 | annotation not available (114 aa) |
| | Mavs | Mitochondrial antiviral-signaling protein isoform X1. (498 aa) |
| | Atp6ap1 | V-type proton ATPase subunit S1. (463 aa) |
| | ENSMAUP00000014844 | annotation not available (634 aa) |
| | Casp9 | Caspase-9; Belongs to the peptidase C14A family. (440 aa) |
| | Tnf | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | Csde1 | Cold shock domain-containing protein E1 isoform X3. (798 aa) |
| | Ifnar1 | Interferon alpha/beta receptor 1. (543 aa) |
| | Nfatc1 | Nuclear factor of activated T-cells, cytoplasmic 1. (898 aa) |
| | Bad | Bcl2-associated agonist of cell death isoform X1. (204 aa) |
| | Tgfbr1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | Sos2 | Son of sevenless homolog 2 isoform X1. (1308 aa) |
| | Slc10a1 | Sodium/bile acid cotransporter. (362 aa) |
| | Prkcb | Protein kinase C beta. (554 aa) |
| | Ccna1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Creb3 | Cyclic AMP-responsive element-binding protein 3 isoform X1. (386 aa) |
| | Ddb1 | DNA damage-binding protein 1 isoform X2. (1140 aa) |
| | Stat2 | Signal transducer and activator of transcription 2. (634 aa) |
| | Nfatc4 | Nuclear factor of activated T-cells, cytoplasmic 4. (728 aa) |
| | ENSMAUP00000012115 | annotation not available (87 aa) |
| | ENSMAUP00000011880 | annotation not available (232 aa) |
| | LOC110339561 | Signal transducer and activator of transcription 5B-like. (125 aa) |
| | Elk1 | ETS domain-containing protein Elk-1. (426 aa) |
| | Mapk3 | Mitogen-activated protein kinase. (380 aa) |
| | Atf4 | Cyclic AMP-dependent transcription factor ATF-4. (350 aa) |
| | Nfatc2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (929 aa) |
| | Map2k2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | Ccne2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | Map2k1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | Tab2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) |
| | Bcl2 | Apoptosis regulator Bcl-2. (236 aa) |
| | Pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | Jak3 | Tyrosine-protein kinase. (1080 aa) |
| | Hspg2 | Basement membrane-specific heparan sulfate proteoglycan core protein. (3785 aa) |
| | Ddb2 | DNA damage-binding protein 2 isoform X1. (387 aa) |
| | Myd88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | Tgfb2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | Vdac3 | Voltage-dependent anion-selective channel protein 3 isoform X2. (283 aa) |
| | Araf | Serine/threonine-protein kinase A-Raf isoform X2. (604 aa) |
| | Jak1 | Tyrosine-protein kinase. (1161 aa) |
| | Src | Tyrosine-protein kinase. (536 aa) |
| | Smad4 | Mothers against decapentaplegic homolog. (552 aa) |
| | ENSMAUP00000008058 | annotation not available (207 aa) |
| | ENSMAUP00000007597 | annotation not available (215 aa) |
| | Fas | Tumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa) |
| | Prkca | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | Stat3 | Signal transducer and activator of transcription. (758 aa) |
| | Creb5 | Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa) |
| | Jak2 | Tyrosine-protein kinase. (1132 aa) |
| | Creb3l2 | Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X2. (520 aa) |
| | Ikbkg | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | Ikbke | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (715 aa) |
| | Bmyc | Protein B-Myc. (173 aa) |
| | Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | Faslg | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa) |
| | Myc | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | Apaf1 | Apoptotic protease-activating factor 1. (222 aa) |
| | Map3k1 | Mitogen-activated protein kinase kinase kinase 1. (1475 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog isoform X1. (589 aa) |
| | LOC101826865 | Cyclic AMP-responsive element-binding protein 3-like protein 4. (213 aa) |
| | LOC106021303 | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa) |
| | Jun | Transcription factor AP-1; Belongs to the bZIP family. (338 aa) |
| | Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
