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Rack1 | Receptor of activated protein C kinase 1. (147 aa) | ||||
Ccne2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) | ||||
Cd209e | CD209 antigen-like protein E. (214 aa) | ||||
LOC110339561 | Signal transducer and activator of transcription 5B-like. (125 aa) | ||||
ENSMAUP00000012115 | annotation not available (87 aa) | ||||
Hspa8 | Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (646 aa) | ||||
Stat2 | Signal transducer and activator of transcription 2. (634 aa) | ||||
Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
Bad | Bcl2-associated agonist of cell death isoform X1. (204 aa) | ||||
Ifnar1 | Interferon alpha/beta receptor 1. (543 aa) | ||||
Oas3 | 2'-5'-oligoadenylate synthase 3 isoform X2. (131 aa) | ||||
Casp9 | Caspase-9; Belongs to the peptidase C14A family. (440 aa) | ||||
Mavs | Mitochondrial antiviral-signaling protein isoform X1. (498 aa) | ||||
ENSMAUP00000015128 | annotation not available (114 aa) | ||||
Eif2s1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) | ||||
Nfkbib | NF-kappa-B inhibitor beta. (358 aa) | ||||
Ikbkb | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa) | ||||
Oas1 | 2'-5'-oligoadenylate synthase 1 isoform X2. (39 aa) | ||||
ENSMAUP00000015826 | annotation not available (113 aa) | ||||
Stat1 | Signal transducer and activator of transcription. (749 aa) | ||||
Bax | Apoptosis regulator BAX isoform X1. (192 aa) | ||||
Fcgr2b | Low affinity immunoglobulin gamma Fc region receptor II-b isoform X2. (340 aa) | ||||
Hspa1l | Heat shock 70 kDa protein 1-like; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis an [...] (629 aa) | ||||
Rela | Transcription factor p65 isoform X1. (260 aa) | ||||
Gsk3b | Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (429 aa) | ||||
Adar | Double-stranded RNA-specific adenosine deaminase isoform X3. (925 aa) | ||||
Irak4 | Interleukin-1 receptor-associated kinase 4. (461 aa) | ||||
Cd209b | CD209 antigen-like protein B isoform X2. (326 aa) | ||||
Cd46 | Membrane cofactor protein. (364 aa) | ||||
ENSMAUP00000017208 | annotation not available (174 aa) | ||||
Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
Cd209a | CD209 antigen-like protein A. (211 aa) | ||||
Cyct | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
Ccnd2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa) | ||||
Irf9 | Interferon regulatory factor 9 isoform X1. (390 aa) | ||||
Map3k7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa) | ||||
Mx2 | Myxovirus (Influenza virus) resistance 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (584 aa) | ||||
Pik3r2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa) | ||||
Mapk10 | Mitogen-activated protein kinase 10. (252 aa) | ||||
Tlr4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa) | ||||
Il2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa) | ||||
Mapk9 | Mitogen-activated protein kinase. (423 aa) | ||||
Chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) | ||||
Tlr9 | Toll-like receptor 9. (1030 aa) | ||||
Il1b | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) | ||||
Il6 | Interleukin-6. (212 aa) | ||||
Ccnd1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) | ||||
Fadd | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
Tlr7 | Toll-like receptor 7 isoform X1; Belongs to the Toll-like receptor family. (1050 aa) | ||||
Tyk2 | Tyrosine-protein kinase. (1190 aa) | ||||
Nfkb1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa) | ||||
Il2rb | Interleukin-2 receptor subunit beta. (415 aa) | ||||
Bak1 | Bcl-2 homologous antagonist/killer. (209 aa) | ||||
Eif3h | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (256 aa) | ||||
Cdkn1b | Cyclin-dependent kinase inhibitor 1B. (198 aa) | ||||
Casp8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa) | ||||
ENSMAUP00000020463 | annotation not available (168 aa) | ||||
Il1a | Interleukin-1; Belongs to the IL-1 family. (269 aa) | ||||
ENSMAUP00000020843 | annotation not available (239 aa) | ||||
ENSMAUP00000021279 | annotation not available (98 aa) | ||||
Cdk2 | Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa) | ||||
Fos | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa) | ||||
Tnfaip3 | Tumor necrosis factor alpha-induced protein 3 isoform X1. (776 aa) | ||||
Rchy1 | RING finger and CHY zinc finger domain-containing protein 1. (259 aa) | ||||
Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
Irf7 | Interferon regulatory factor 7 isoform X1. (394 aa) | ||||
Cd28 | T-cell-specific surface glycoprotein CD28. (219 aa) | ||||
Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
Cdk6 | Cyclin-dependent kinase 6. (203 aa) | ||||
Pik3r2-2 | Phosphoinositide-3-kinase regulatory subunit 2. (71 aa) | ||||
Csnk2b | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa) | ||||
Traf3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa) | ||||
LOC101823672 | 2'-5'-oligoadenylate synthase 1A-like. (157 aa) | ||||
ENSMAUP00000025153 | annotation not available (525 aa) | ||||
Ddx58 | Putative ATP-dependent RNA helicase DDX58. (908 aa) | ||||
ENSMAUP00000025330 | annotation not available (154 aa) | ||||
Csnk2a1 | LOW QUALITY PROTEIN: casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (380 aa) | ||||
Irf3 | Interferon regulatory factor 3 isoform X1. (420 aa) | ||||
Tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (395 aa) | ||||
Il2ra | Interleukin-2 receptor subunit alpha. (267 aa) | ||||
Eif2ak1 | Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (622 aa) | ||||
Hspa2 | Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (633 aa) | ||||
Ccne1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) | ||||
ENSMAUP00000003031 | annotation not available (117 aa) | ||||
Irak1 | Interleukin-1 receptor-associated kinase 1 isoform X2. (747 aa) | ||||
LOC101831400 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa) | ||||
Dhdh | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa) | ||||
LOC106021986 | 2'-5'-oligoadenylate synthase 1A-like. (280 aa) | ||||
Clec4g | C-type lectin domain family 4 member G. (293 aa) | ||||
LOC101835654 | Signal transducer and activator of transcription. (228 aa) | ||||
Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
ENSMAUP00000001870 | annotation not available (99 aa) | ||||
Slamf1 | Signaling lymphocytic activation molecule. (339 aa) | ||||
Tlr2 | Toll-like receptor. (784 aa) | ||||
LOC101842058 | Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
Eif2ak3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (1095 aa) | ||||
Tbk1 | Serine/threonine-protein kinase TBK1. (729 aa) | ||||
ENSMAUP00000000683 | annotation not available (256 aa) | ||||
Tradd | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa) | ||||
Eif2ak2 | Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (517 aa) | ||||
Mx1 | Interferon-induced GTP-binding protein Mx1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (577 aa) | ||||
Bcl2l1 | Bcl-2-like protein 1. (233 aa) | ||||
LOC101824534 | Interferon alpha-12-like. (183 aa) | ||||
Casp3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (246 aa) | ||||
Eif2ak4 | eIF-2-alpha kinase GCN2. (1510 aa) | ||||
Traf6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa) | ||||
Nfkbia | NF-kappa-B inhibitor alpha. (314 aa) | ||||
LOC101842510 | Signal transducer and activator of transcription 5A. (228 aa) | ||||
Mapk8 | Mitogen-activated protein kinase. (427 aa) | ||||
Il12a | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (206 aa) | ||||
Msn | Moesin. (579 aa) | ||||
Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
Jun | Transcription factor AP-1; Belongs to the bZIP family. (338 aa) | ||||
LOC106021303 | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa) | ||||
CUNH7orf31 | Uncharacterized protein C7orf31 homolog isoform X1. (589 aa) | ||||
LOC106021992 | 2'-5'-oligoadenylate synthase 1A-like. (296 aa) | ||||
Apaf1 | Apoptotic protease-activating factor 1. (222 aa) | ||||
Cd3d | T-cell surface glycoprotein CD3 delta chain precursor. (171 aa) | ||||
Faslg | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa) | ||||
Csnk2a2 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (325 aa) | ||||
Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) | ||||
Ikbke | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (715 aa) | ||||
Cd3g | T-cell surface glycoprotein CD3 gamma chain. (182 aa) | ||||
Ikbkg | NF-kappa-B essential modulator isoform X1. (412 aa) | ||||
Stat3 | Signal transducer and activator of transcription. (758 aa) | ||||
Fas | Tumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa) | ||||
Bbc3 | Bcl-2-binding component 3 isoform X2. (193 aa) | ||||
Cd3e | T-cell surface glycoprotein CD3 epsilon chain. (188 aa) | ||||
Oas2 | 2'-5'-oligoadenylate synthase 2 isoform X1. (725 aa) | ||||
Jak1 | Tyrosine-protein kinase. (1161 aa) | ||||
Myd88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) | ||||
Rab9b | Ras-related protein Rab-9B. (201 aa) | ||||
Ccnd3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) | ||||
Jak3 | Tyrosine-protein kinase. (1080 aa) | ||||
Tp73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (286 aa) | ||||
Cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
Bcl2 | Apoptosis regulator Bcl-2. (236 aa) | ||||
Tab2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) | ||||
Il2rg | Cytokine receptor common subunit gamma isoform X1. (363 aa) |