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| | Hdac1 | Histone deacetylase 1. (303 aa) |
| | LOC101823672 | 2'-5'-oligoadenylate synthase 1A-like. (157 aa) |
| | Traf3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa) |
| | Pik3r2-2 | Phosphoinositide-3-kinase regulatory subunit 2. (71 aa) |
| | Cdk6 | Cyclin-dependent kinase 6. (203 aa) |
| | Entpd3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | ENSMAUP00000024144 | annotation not available (159 aa) |
| | Map2k6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa) |
| | Rb1 | Retinoblastoma-associated protein. (906 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Cc2d2b | Protein CC2D2B isoform X1. (1000 aa) |
| | Rbpj | Recombining binding protein suppressor of hairless isoform X1. (526 aa) |
| | Hdac2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | H2-Ab1 | Rano class II histocompatibility antigen, A beta chain-like. (263 aa) |
| | Map2k3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | Irf9 | Interferon regulatory factor 9 isoform X1. (390 aa) |
| | Cd247 | LOW QUALITY PROTEIN: T-cell surface glycoprotein CD3 zeta chain. (163 aa) |
| | Gadd45g | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | ENSMAUP00000022538 | annotation not available (95 aa) |
| | Irf7 | Interferon regulatory factor 7 isoform X1. (394 aa) |
| | Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | Psmd4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa) |
| | Psmc1 | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa) |
| | E2f3 | Transcription factor E2F3 isoform X1. (460 aa) |
| | Tnfaip3 | Tumor necrosis factor alpha-induced protein 3 isoform X1. (776 aa) |
| | Cir1 | Corepressor interacting with RBPJ 1. (276 aa) |
| | Cdk2 | Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa) |
| | LOC101832695 | H-2 class I histocompatibility antigen, D-37 alpha chain-like isoform X1; Belongs to the MHC class I family. (248 aa) |
| | Psmd11 | 26S proteasome non-ATPase regulatory subunit 11. (419 aa) |
| | Syk | Tyrosine-protein kinase. (629 aa) |
| | ENSMAUP00000021279 | annotation not available (98 aa) |
| | Psmd8 | 26S proteasome non-ATPase regulatory subunit 8. (180 aa) |
| | Calr | Calreticulin. (283 aa) |
| | ENSMAUP00000020463 | annotation not available (168 aa) |
| | Casp8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa) |
| | ENSMAUP00000020392 | annotation not available (68 aa) |
| | LOC101826335 | Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family. (317 aa) |
| | Cdkn1b | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | Ccna2 | Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa) |
| | Bak1 | Bcl-2 homologous antagonist/killer. (209 aa) |
| | LOC101843733 | H-2 class II histocompatibility antigen, E-D beta chain-like. (181 aa) |
| | Nfkb1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa) |
| | Tyk2 | Tyrosine-protein kinase. (1190 aa) |
| | Tap1 | Antigen peptide transporter 1. (716 aa) |
| | Fadd | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | Ccnd1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | Rac1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa) |
| | Il6 | Interleukin-6. (212 aa) |
| | Chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) |
| | Mapk9 | Mitogen-activated protein kinase. (423 aa) |
| | Mapk13 | Mitogen-activated protein kinase. (366 aa) |
| | Relb | Transcription factor RelB. (191 aa) |
| | Mapk10 | Mitogen-activated protein kinase 10. (252 aa) |
| | Snw1 | SNW domain-containing protein 1. (536 aa) |
| | Pik3r2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa) |
| | LOC101832429 | H-2 class I histocompatibility antigen, Q9 alpha chain-like; Belongs to the MHC class I family. (205 aa) |
| | Map3k7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa) |
| | Ccnd2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa) |
| | Calr4 | Calreticulin-like. (281 aa) |
| | Cyct | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | Polk | DNA polymerase kappa. (856 aa) |
| | Psmd1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa) |
| | Nfkb2 | Nuclear factor NF-kappa-B p100 subunit isoform X2. (898 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Sem1 | 26S proteasome complex subunit SEM1. (70 aa) |
| | ENSMAUP00000017208 | annotation not available (174 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (360 aa) |
| | Irak4 | Interleukin-1 receptor-associated kinase 4. (461 aa) |
| | Rela | Transcription factor p65 isoform X1. (260 aa) |
| | Btk | Tyrosine-protein kinase. (659 aa) |
| | Fcer2 | Low affinity immunoglobulin epsilon Fc receptor isoform X1. (330 aa) |
| | Bax | Apoptosis regulator BAX isoform X1. (192 aa) |
| | Gadd45b | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | Stat1 | Signal transducer and activator of transcription. (749 aa) |
| | Tap2 | Antigen peptide transporter 2 isoform X1. (704 aa) |
| | Oas1 | 2'-5'-oligoadenylate synthase 1 isoform X2. (39 aa) |
| | Ikbkb | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa) |
| | Nfkbib | NF-kappa-B inhibitor beta. (358 aa) |
| | Osbpl2 | Oxysterol-binding protein; Belongs to the OSBP family. (483 aa) |
| | Mavs | Mitochondrial antiviral-signaling protein isoform X1. (498 aa) |
| | H2-Ea-ps | H-2 class II histocompatibility antigen, E-U alpha chain; Belongs to the MHC class II family. (256 aa) |
| | ENSMAUP00000014706 | annotation not available (414 aa) |
| | Psmd2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa) |
| | Casp9 | Caspase-9; Belongs to the peptidase C14A family. (440 aa) |
| | Tnf | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | Psmd3 | 26S proteasome non-ATPase regulatory subunit 3. (530 aa) |
| | Cxcl10 | C-X-C motif chemokine. (98 aa) |
| | ENSMAUP00000014414 | annotation not available (313 aa) |
| | Psmd14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | Oas3 | 2'-5'-oligoadenylate synthase 3 isoform X2. (131 aa) |
| | Ifnar1 | Interferon alpha/beta receptor 1. (543 aa) |
| | H2-Oa | HLA class II histocompatibility antigen, DO alpha chain isoform X1; Belongs to the MHC class II family. (250 aa) |
| | Ncor2 | Nuclear receptor corepressor 2 isoform X13. (2511 aa) |
| | Hes1 | Transcription factor HES-1. (281 aa) |
| | Psmd12 | 26S proteasome non-ATPase regulatory subunit 12. (308 aa) |
| | Sap30 | Histone deacetylase complex subunit SAP30. (225 aa) |
| | Ccna1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Gadd45a | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | Stat2 | Signal transducer and activator of transcription 2. (634 aa) |
| | Sin3a | Paired amphipathic helix protein Sin3a. (1076 aa) |
| | Psmc5 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | ENSMAUP00000012115 | annotation not available (87 aa) |
| | Cd40 | Tumor necrosis factor receptor superfamily member 5 isoform X2. (290 aa) |
| | Psmd6 | 26S proteasome non-ATPase regulatory subunit 6. (389 aa) |
| | Psmd7 | 26S proteasome non-ATPase regulatory subunit 7. (320 aa) |
| | Nfkbie | NF-kappa-B inhibitor epsilon. (362 aa) |
| | Apaf1 | Apoptotic protease-activating factor 1. (222 aa) |
| | Ighm | Ig mu chain C region. (454 aa) |
| | LOC106021992 | 2'-5'-oligoadenylate synthase 1A-like. (296 aa) |
| | H2-Ob | HLA class II histocompatibility antigen, DO beta chain. (274 aa) |
| | Plcg2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | Entpd8 | Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (494 aa) |
| | Psmc3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog isoform X1. (589 aa) |
| | LOC106021303 | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa) |
| | Jun | Transcription factor AP-1; Belongs to the bZIP family. (338 aa) |
| | Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | Map3k14 | Mitogen-activated protein kinase kinase kinase 14. (941 aa) |
| | Mapk8 | Mitogen-activated protein kinase. (427 aa) |
| | Icam1 | Intercellular adhesion molecule 1 isoform X2. (516 aa) |
| | Nfkbia | NF-kappa-B inhibitor alpha. (314 aa) |
| | Tapbp | Tapasin. (456 aa) |
| | Traf6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa) |
| | ENSMAUP00000004122 | annotation not available (116 aa) |
| | Casp3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (246 aa) |
| | LOC101824534 | Interferon alpha-12-like. (183 aa) |
| | Vim | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa) |
| | Cd44 | CD44 antigen; Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its c [...] (431 aa) |
| | Lyn | Tyrosine-protein kinase. (438 aa) |
| | E2f2 | Transcription factor E2F2 isoform X1. (449 aa) |
| | Nedd4 | E3 ubiquitin-protein ligase. (849 aa) |
| | H2-M2 | Class I histocompatibility antigen, Non-RT1.A alpha-1 chain-like; Belongs to the MHC class I family. (301 aa) |
| | Map2k7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (520 aa) |
| | H2-Aa | H-2 class II histocompatibility antigen, A-U alpha chain. (173 aa) |
| | Ccne1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | Irak1 | Interleukin-1 receptor-associated kinase 1 isoform X2. (747 aa) |
| | LOC101831400 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa) |
| | Dhdh | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa) |
| | LOC106021986 | 2'-5'-oligoadenylate synthase 1A-like. (280 aa) |
| | Skp2 | S-phase kinase-associated protein 2. (354 aa) |
| | Entpd1 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (541 aa) |
| | Sap30l | Histone deacetylase complex subunit SAP30L. (182 aa) |
| | Psmd13 | 26S proteasome non-ATPase regulatory subunit 13. (369 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ENSMAUP00000001870 | annotation not available (99 aa) |
| | Traf5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (550 aa) |
| | Tlr2 | Toll-like receptor. (784 aa) |
| | Cdkn1a | Cyclin-dependent kinase inhibitor 1. (163 aa) |
| | E2f1 | Transcription factor E2F1. (383 aa) |
| | Traf2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | H2-DMa | Class II histocompatibility antigen, M alpha chain; Belongs to the MHC class II family. (261 aa) |
| | LOC101827397 | HLA class I histocompatibility antigen, alpha chain F-like; Belongs to the MHC class I family. (202 aa) |
| | LOC101842058 | Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | Tbk1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | Ripk1 | Receptor-interacting serine/threonine-protein kinase 1. (658 aa) |
| | Tradd | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa) |
| | Eif2ak2 | Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (517 aa) |
| | ENSMAUP00000000027 | annotation not available (338 aa) |
| | Ikbkg | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | Stat3 | Signal transducer and activator of transcription. (758 aa) |
| | Fas | Tumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa) |
| | ENSMAUP00000007177 | annotation not available (91 aa) |
| | Psmc4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | Cc2d2a | Coiled-coil and C2 domain-containing protein 2A isoform X1. (1631 aa) |
| | Isg15 | Ubiquitin-like protein ISG15. (160 aa) |
| | Bcl2l11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (197 aa) |
| | Cd3e | T-cell surface glycoprotein CD3 epsilon chain. (188 aa) |
| | ENSMAUP00000008458 | annotation not available (123 aa) |
| | Cr2 | Complement receptor type 2 isoform X1. (1410 aa) |
| | Sin3b | Paired amphipathic helix protein Sin3b isoform X1. (1095 aa) |
| | LOC101831377 | H-2 class I histocompatibility antigen, Q10 alpha chain-like; Belongs to the MHC class I family. (210 aa) |
| | Oas2 | 2'-5'-oligoadenylate synthase 2 isoform X1. (725 aa) |
| | Jak1 | Tyrosine-protein kinase. (1161 aa) |
| | LOC101831914 | H-2 class I histocompatibility antigen, Q10 alpha chain-like; Belongs to the MHC class I family. (351 aa) |
| | Myd88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | Ddb2 | DNA damage-binding protein 2 isoform X1. (387 aa) |
| | Ccnd3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | Jak3 | Tyrosine-protein kinase. (1080 aa) |
| | Runx3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (420 aa) |
| | Cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | Itgal | Integrin alpha-L; Belongs to the integrin alpha chain family. (1159 aa) |
| | Bcl2 | Apoptosis regulator Bcl-2. (236 aa) |
| | Pdia3 | Protein disulfide-isomerase. (468 aa) |
| | Tab2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) |
| | Ccne2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | Cd3g | T-cell surface glycoprotein CD3 gamma chain. (182 aa) |
| | Ikbke | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (715 aa) |
| | Bmyc | Protein B-Myc. (173 aa) |
| | Usp7 | Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (496 aa) |
| | Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | Psmc2 | Proteasome 26S subunit, ATPase 2. (349 aa) |
| | Cd3d | T-cell surface glycoprotein CD3 delta chain precursor. (171 aa) |
| | H2-T24 | H-2 class I histocompatibility antigen, Q7 alpha chain-like; Belongs to the MHC class I family. (345 aa) |
| | Psmc6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa) |
| | Myc | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | Mapk11 | Mitogen-activated protein kinase. (355 aa) |
| | Tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (395 aa) |
| | B2m | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (270 aa) |
| | Irf3 | Interferon regulatory factor 3 isoform X1. (420 aa) |
| | Mapk12 | Mitogen-activated protein kinase. (367 aa) |
| | Tab1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (254 aa) |
| | Adrm1 | Proteasomal ubiquitin receptor ADRM1. (407 aa) |
| | Blnk | B-cell linker protein. (457 aa) |
| | Ddx58 | Putative ATP-dependent RNA helicase DDX58. (908 aa) |
