(6 nodes) Proline metabolic process, and Alkali metal ion binding network (Gallibacterium anatis)

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Your Input:
	AEC16763.1	Sodium/panthothenate symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (501 aa)
	AEC16764.1	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1146 aa)
	proA	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
	proB	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (364 aa)
	proC	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa)
	AEC17984.1	Ornithine cyclodeaminase. (325 aa)

Your Current Organism:

Gallibacterium anatis

NCBI taxonomy Id: 1005058
Other names: G. anatis UMN179, Gallibacterium anatis UMN179, Gallibacterium anatis str. UMN179, Gallibacterium anatis strain UMN179

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEC16763.1	AEC16764.1	UMN179_00732	UMN179_00733	Sodium/panthothenate symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.988
AEC16764.1	AEC16763.1	UMN179_00733	UMN179_00732	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Sodium/panthothenate symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.988
AEC16764.1	AEC17984.1	UMN179_00733	UMN179_01971	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Ornithine cyclodeaminase.	0.944
AEC16764.1	proA	UMN179_00733	UMN179_01362	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.938
AEC16764.1	proB	UMN179_00733	UMN179_01363	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.941
AEC16764.1	proC	UMN179_00733	UMN179_01428	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.953
AEC17984.1	AEC16764.1	UMN179_01971	UMN179_00733	Ornithine cyclodeaminase.	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.944
AEC17984.1	proC	UMN179_01971	UMN179_01428	Ornithine cyclodeaminase.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.928
proA	AEC16764.1	UMN179_01362	UMN179_00733	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.938
proA	proB	UMN179_01362	UMN179_01363	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.999
proA	proC	UMN179_01362	UMN179_01428	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.825
proB	AEC16764.1	UMN179_01363	UMN179_00733	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.941
proB	proA	UMN179_01363	UMN179_01362	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.999
proB	proC	UMN179_01363	UMN179_01428	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.833
proC	AEC16764.1	UMN179_01428	UMN179_00733	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.953
proC	AEC17984.1	UMN179_01428	UMN179_01971	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Ornithine cyclodeaminase.	0.928
proC	proA	UMN179_01428	UMN179_01362	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.825
proC	proB	UMN179_01428	UMN179_01363	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.833