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rplK rplK rplA rplA rplJ rplJ rplL rplL rpsF rpsF rpsR rpsR rplI rplI rpsU rpsU rpsB rpsB rpsA rpsA rpmF rpmF rpmI rpmI rplT rplT rplY rplY rplS rplS rpsP rpsP rpsT rpsT rpsO rpsO rpmA rpmA rplU rplU rpsI rpsI rplM rplM rplQ rplQ rpsD rpsD rpsK rpsK rpsM rpsM rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN rpsN rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ rpsG rpsG rpsL rpsL rpmH rpmH rpmB rpmB rpmG rpmG rpmE rpmE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplKLSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
rplALSU ribosomal protein L1p (L10Ae); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa)
rplJLSU ribosomal protein L10p (P0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa)
rplLLSU ribosomal protein L7/L12 (P1/P2); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa)
rpsFSSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA. (131 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa)
rplILSU ribosomal protein L9p; Binds to the 23S rRNA. (150 aa)
rpsUSSU ribosomal protein S21p; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family. (71 aa)
rpsBSSU ribosomal protein S2p; Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uS2 family. (241 aa)
rpsASSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (558 aa)
rpmFLSU ribosomal protein L32p; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL32 family. (56 aa)
rpmILSU ribosomal protein L35p; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
rplTLSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
rplYLSU ribosomal protein L25p; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa)
rplSLSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa)
rpsPSSU ribosomal protein S16p; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS16 family. (82 aa)
rpsTSSU ribosomal protein S20p; Binds directly to 16S ribosomal RNA. (87 aa)
rpsOSSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
rpmALSU ribosomal protein L27p; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL27 family. (85 aa)
rplULSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa)
rpsISSU ribosomal protein S9p (S16e); Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplMLSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rplQLSU ribosomal protein L17p; Protein involved in structural constituent of ribosome and translation. (128 aa)
rpsDSSU ribosomal protein S4p (S9e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)
rpsKSSU ribosomal protein S11p (S14e); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsMSSU ribosomal protein S13p (S18e); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa)
rplOLSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rpmDLSU ribosomal protein L30p (L7e); Protein involved in structural constituent of ribosome and translation. (59 aa)
rpsESSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (166 aa)
rplRLSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa)
rplFLSU ribosomal protein L6p (L9e); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpsHSSU ribosomal protein S8p (S15Ae); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpsNS14p (S29e) family SSU ribosomal protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rplELSU ribosomal protein L5p (L11e); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rplXLSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa)
rplNLSU ribosomal protein L14p (L23e); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (117 aa)
rpsQSSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa)
rpmCLSU ribosomal protein L29p (L35e); Protein involved in structural constituent of ribosome and translation; Belongs to the universal ribosomal protein uL29 family. (63 aa)
rplPLSU ribosomal protein L16p (L10e); Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa)
rpsCSSU ribosomal protein S3p (S3e); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (233 aa)
rplVLSU ribosomal protein L22p (L17e); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa)
rpsSSSU ribosomal protein S19p (S15e); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplBLSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa)
rplWLSU ribosomal protein L23p (L23Ae); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplDLSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel. (201 aa)
rplCLSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa)
rpsJSSU ribosomal protein S10p (S20e); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa)
rpsGSSU ribosomal protein S7p (S5e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsLSSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa)
rpmHLSU ribosomal protein L34p; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL34 family. (46 aa)
rpmBLSU ribosomal protein L28p; Protein involved in structural constituent of ribosome and translation. (66 aa)
rpmGL33p family LSU ribosomal protein; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
rpmEL31p family LSU ribosomal protein; Binds the 23S rRNA. (71 aa)
Your Current Organism:
Buttiauxella agrestis
NCBI taxonomy Id: 1006004
Other names: B. agrestis ATCC 33320, Buttiauxella agrestis ATCC 33320, Buttiauxella agrestis CDC 11786-81, Buttiauxella agrestis CIP 80.31, Buttiauxella agrestis CUETM 77-167, Buttiauxella agrestis DSM 4586, Buttiauxella agrestis str. ATCC 33320, Buttiauxella agrestis strain ATCC 33320
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