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| | PT7_0028 | Metallophosphoesterase. (262 aa) |
| | PT7_0029 | Hypothetical protein. (53 aa) |
| | metN | Amino-acid ABC transporter ATP-binding protein y4tH; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (320 aa) |
| | PT7_0031 | Binding-protein-dependent transport systems inner membrane component. (219 aa) |
| | PT7_0032 | Exported protein. (261 aa) |
| | pcnB | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (453 aa) |
| | PT7_0060 | Hypothetical protein. (233 aa) |
| | PT7_0061 | Hypothetical protein; Belongs to the DnaA family. (233 aa) |
| | PT7_0152 | Acetylornithine deacetylase. (382 aa) |
| | PT7_0156 | Cystathionine beta-lyase. (403 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa) |
| | cysI | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (567 aa) |
| | PT7_0174 | Sulfite reductase flavoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (603 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (483 aa) |
| | PT7_0215 | Aspartate kinase; Belongs to the aspartokinase family. (420 aa) |
| | dapA-2 | Dihydrodipicolinate synthetase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | PT7_0371 | Hypothetical protein; Belongs to the aldehyde dehydrogenase family. (493 aa) |
| | PT7_0372 | Putative hydrolase. (399 aa) |
| | PT7_0459 | Thiosulfate sulfurtransferase. (289 aa) |
| | PT7_0474 | Aminotransferase. (395 aa) |
| | PT7_0475 | Homoserine dehydrogenase. (434 aa) |
| | PT7_0476 | Threonine synthase. (469 aa) |
| | argA | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. (473 aa) |
| | PT7_0601 | Hypothetical protein; Belongs to the glutamate synthase family. (564 aa) |
| | PT7_0607 | Hypothetical protein. (409 aa) |
| | PT7_0640 | Sodium transporter family protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (479 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (445 aa) |
| | PT7_0683 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (314 aa) |
| | PT7_0706 | Pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1271 aa) |
| | PT7_0722 | ABC transporter ATP-binding protein. (644 aa) |
| | prmB | Heme biosynthesis protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. (298 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (378 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | PT7_0726 | N-succinyl-L,L-diaminopimelate aminotransferase. (418 aa) |
| | PT7_0732 | Hypothetical protein. (60 aa) |
| | PT7_0737 | Aromatic amino acid aminotransferase. (400 aa) |
| | PT7_0820 | Serine O-acetyltransferase. (312 aa) |
| | PT7_0948 | Cyclohexadienyl dehydratase. (257 aa) |
| | PT7_0956 | Dihydrodipicolinate synthase; Belongs to the DapA family. (298 aa) |
| | argH | Argininosuccinate lyase. (472 aa) |
| | cysA | ABC transporter; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (374 aa) |
| | PT7_1068 | Sulfate ABC transporter, permease protein. (310 aa) |
| | PT7_1069 | Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (287 aa) |
| | PT7_1070 | Sulfate ABC transporter periplasmic sulfate-binding protein. (336 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (277 aa) |
| | PT7_1194 | Glutamine synthetase. (470 aa) |
| | PT7_1257 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (461 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (219 aa) |
| | PT7_1288 | Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (364 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (352 aa) |
| | thrB | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. (321 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (764 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (388 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa) |
| | PT7_1431 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa) |
| | PT7_1478 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa) |
| | aroA | 5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (441 aa) |
| | PT7_1488 | Prephenate dehydrogenase. (302 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (379 aa) |
| | PT7_1490 | P-protein. (361 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (375 aa) |
| | PT7_1617 | Mandelate racemase/muconate lactonizing protein. (374 aa) |
| | PT7_1618 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (303 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (430 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (282 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (354 aa) |
| | PT7_1749 | Phosphoserine phosphatase. (283 aa) |
| | PT7_1798 | Cystathionine beta-lyase. (412 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa) |
| | PT7_1976 | Binding-protein-dependent transport systems inner membrane component. (216 aa) |
| | PT7_2023 | Putative glycosyl transferase. (314 aa) |
| | PT7_2024 | Hypothetical protein. (42 aa) |
| | PT7_2026 | Aminodeoxychorismate synthase. (384 aa) |
| | PT7_2027 | Hypothetical protein. (223 aa) |
| | PT7_2028 | Transporter. (110 aa) |
| | PT7_2029 | Hypothetical protein. (216 aa) |
| | PT7_2113 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (399 aa) |
| | PT7_2176 | Proline iminopeptidase; Belongs to the peptidase S33 family. (310 aa) |
| | PT7_2246 | Putative thiosulfate sulfurtransferase. (311 aa) |
| | PT7_2459 | CDP-6-deoxy-delta-3,4-glucoseen reductase. (346 aa) |
| | PT7_2465 | Putative hydroxylase. (135 aa) |
| | PT7_2466 | Putative dioxygenase subunit. (410 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (506 aa) |
| | PT7_2534 | Anthranilate synthase component II. (187 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (343 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | PT7_2537 | Hypothetical protein. (492 aa) |
| | PT7_2538 | Hypothetical protein. (164 aa) |
| | PT7_2549 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (281 aa) |
| | ahcY | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (475 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (407 aa) |
| | PT7_2586 | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (431 aa) |
| | PT7_2587 | Sulfate adenylyltransferase subunit 2. (302 aa) |
| | PT7_2588 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (256 aa) |
| | PT7_2589 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (429 aa) |
| | glmS | D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa) |
| | PT7_2802 | Shikimate dehydrogenase substrate binding subunit. (267 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (198 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | argD | Acetylornithine transaminase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa) |
| | PT7_3049 | Cystathionine beta-lyase. (399 aa) |
| | PT7_3097 | Hypothetical protein. (812 aa) |
| | tatC | Putative Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (268 aa) |
| | tatB | Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (156 aa) |
| | tatA | Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (76 aa) |
| | PT7_3114 | Hypothetical protein. (122 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphohydrolase. (115 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (134 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (267 aa) |
| | hisA | Histidine biosynthesis protein. (247 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (438 aa) |
| | hisG | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (224 aa) |
| | PT7_3124 | BolA-like protein; Belongs to the BolA/IbaG family. (82 aa) |
| | PT7_3125 | Putative ABC-2 type transporter protein. (264 aa) |
| | PT7_3126 | ABC transporter ATP-binding protein. (267 aa) |
| | PT7_3127 | Exported protein. (219 aa) |
| | PT7_3128 | Hypothetical protein. (285 aa) |
| | PT7_3129 | Virulence protein transporter. (167 aa) |
| | PT7_3130 | Hypothetical protein. (262 aa) |
| | PT7_3131 | Putative ABC transport system ATP-binding protein. (275 aa) |
| | PT7_3135 | Glutamate synthase [NADPH] small chain precursor. (487 aa) |
| | PT7_3136 | Glutamate synthase [NADPH] large chain precursor. (1498 aa) |
| | PT7_3242 | Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (501 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (290 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (286 aa) |
| | PT7_3398 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1257 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (393 aa) |
| | argJ | Arginine biosynthesis bifunctional protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (378 aa) |
| | PT7_3588 | N-acetyltransferase. (144 aa) |
| | PT7_3600 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (304 aa) |
| | PT7_3618 | O-acetylhomoserine aminocarboxypropyltransferase. (425 aa) |
| | PT7_3660 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (327 aa) |
