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PT7_0053 PT7_0053 PT7_0104 PT7_0104 PT7_0408 PT7_0408 mdh mdh PT7_0420 PT7_0420 PT7_0421 PT7_0421 PT7_0422 PT7_0422 PT7_0423 PT7_0423 PT7_0425 PT7_0425 PT7_0428 PT7_0428 PT7_0429 PT7_0429 PT7_0430 PT7_0430 PT7_0431 PT7_0431 PT7_0453 PT7_0453 PT7_0836 PT7_0836 PT7_0837 PT7_0837 PT7_0838 PT7_0838 PT7_0839 PT7_0839 PT7_1009 PT7_1009 PT7_1016 PT7_1016 PT7_1017 PT7_1017 PT7_1018 PT7_1018 fumC fumC sucD sucD sucC sucC PT7_1574 PT7_1574 PT7_1922 PT7_1922 PT7_2054 PT7_2054 PT7_2085 PT7_2085 gcvP gcvP gcvH gcvH gcvT gcvT PT7_2481 PT7_2481 PT7_2482 PT7_2482 PT7_2483 PT7_2483 PT7_2484 PT7_2484 PT7_2612 PT7_2612 PT7_2643 PT7_2643 PT7_2645 PT7_2645 PT7_2646 PT7_2646 PT7_2789 PT7_2789 PT7_2790 PT7_2790 PT7_2792 PT7_2792 PT7_2882 PT7_2882 PT7_2935 PT7_2935 PT7_3016 PT7_3016 PT7_3435 PT7_3435
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
PT7_0053Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa)
PT7_0104Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (503 aa)
PT7_0408Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (865 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
PT7_0420Succinate dehydrogenase cytochrome B subunit. (104 aa)
PT7_0421Succinate dehydrogenase hydrophobic membrane anchor subunit. (126 aa)
PT7_0422Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (591 aa)
PT7_0423Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
PT7_0425Type II citrate synthase; Belongs to the citrate synthase family. (434 aa)
PT7_0428Malic enzyme. (765 aa)
PT7_0429Alpha-ketoglutarate decarboxylase. (956 aa)
PT7_0430Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (398 aa)
PT7_0431Dihydrolipoamide dehydrogenase. (475 aa)
PT7_0453Succinic semialdehyde dehydrogenase. (479 aa)
PT7_08363-methyl-2-oxobutanoate dehydrogenase. (410 aa)
PT7_0837Transketolase. (357 aa)
PT7_0838Hypothetical protein. (431 aa)
PT7_0839Dihydrolipoamide dehydrogenase. (471 aa)
PT7_1009Mercuric ion reductase. (479 aa)
PT7_1016Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (903 aa)
PT7_1017Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (572 aa)
PT7_1018Dihydrolipoamide dehydrogenase. (581 aa)
fumC3-carboxy-cis,cis-muconate cycloisomerase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCSuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
PT7_1574Serine-glyoxylate aminotransferase. (401 aa)
PT7_1922Isocitrate dehydrogenase. (418 aa)
PT7_2054Malic enzyme. (764 aa)
PT7_2085Malic enzyme. (760 aa)
gcvPGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (968 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
PT7_2481Hypothetical protein. (84 aa)
PT7_2482Succinate dehydrogenase, hydrophobic membrane anchor protein, putative. (137 aa)
PT7_2483Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (598 aa)
PT7_2484Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
PT7_2612Aconitate hydratase. (937 aa)
PT7_2643Dihydrolipoamide acyltransferase (E2) component of 2-oxoacid dehydrogenase complexes. (433 aa)
PT7_2645Putative 2-oxo acid dehydrogenase beta subunit. (323 aa)
PT7_2646Putative 2-oxo acid dehydrogenase alpha subunit. (322 aa)
PT7_2789Dihydrolipoamide dehydrogenase. (463 aa)
PT7_2790Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (420 aa)
PT7_27922-oxoisovalerate dehydrogenase beta subunit. (733 aa)
PT7_2882Aldehyde dehydrogenase family protein. (475 aa)
PT7_2935Citrate synthase. (255 aa)
PT7_30162-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (905 aa)
PT7_34352-oxoisovalerate dehydrogenase beta subunit. (731 aa)
Your Current Organism:
Pusillimonas sp. T77
NCBI taxonomy Id: 1007105
Other names: P. sp. T7-7, Pusillimonas sp. T7-7
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