(11 nodes) acyl-CoA biosynthetic process, and Biotin-requiring enzyme network (Pusillimonas sp. T77)

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Your Input:
	PT7_0129	acetyl-CoA synthetase. (545 aa)
	accA	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
	PT7_0495	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	PT7_1650	acetyl-CoA synthetase. (450 aa)
	acsA	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (659 aa)
	accD	acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa)
	PT7_2249	Citrate synthase. (271 aa)
	PT7_3232	Putative allophanate hydrolase. (73 aa)
	PT7_3438	Branched-chain alpha-keto acid dehydrogenase subunit E2. (390 aa)
	PT7_3512	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (145 aa)
	PT7_3513	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)

Your Current Organism:

Pusillimonas sp. T77

NCBI taxonomy Id: 1007105
Other names: P. sp. T7-7, Pusillimonas sp. T7-7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PT7_0129	PT7_0495	PT7_0129	PT7_0495	acetyl-CoA synthetase.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.946
PT7_0129	PT7_1650	PT7_0129	PT7_1650	acetyl-CoA synthetase.	acetyl-CoA synthetase.	0.913
PT7_0129	PT7_2249	PT7_0129	PT7_2249	acetyl-CoA synthetase.	Citrate synthase.	0.951
PT7_0129	PT7_3232	PT7_0129	PT7_3232	acetyl-CoA synthetase.	Putative allophanate hydrolase.	0.916
PT7_0129	PT7_3438	PT7_0129	PT7_3438	acetyl-CoA synthetase.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.908
PT7_0129	PT7_3512	PT7_0129	PT7_3512	acetyl-CoA synthetase.	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.906
PT7_0129	PT7_3513	PT7_0129	PT7_3513	acetyl-CoA synthetase.	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.926
PT7_0129	accA	PT7_0129	PT7_0213	acetyl-CoA synthetase.	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.906
PT7_0129	accD	PT7_0129	PT7_1710	acetyl-CoA synthetase.	acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.911
PT7_0129	acsA	PT7_0129	PT7_1665	acetyl-CoA synthetase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.917
PT7_0495	PT7_0129	PT7_0495	PT7_0129	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA synthetase.	0.946
PT7_0495	PT7_1650	PT7_0495	PT7_1650	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA synthetase.	0.942
PT7_0495	PT7_2249	PT7_0495	PT7_2249	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Citrate synthase.	0.925
PT7_0495	PT7_3232	PT7_0495	PT7_3232	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative allophanate hydrolase.	0.730
PT7_0495	PT7_3438	PT7_0495	PT7_3438	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.674
PT7_0495	PT7_3512	PT7_0495	PT7_3512	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.669
PT7_0495	PT7_3513	PT7_0495	PT7_3513	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.697
PT7_0495	accA	PT7_0495	PT7_0213	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.662
PT7_0495	accD	PT7_0495	PT7_1710	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.	0.679
PT7_0495	acsA	PT7_0495	PT7_1665	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.931