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| | PT7_0411 | Hypothetical protein. (485 aa) |
| | PT7_0046 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (131 aa) |
| | PT7_0053 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa) |
| | PT7_0055 | Hypothetical protein. (284 aa) |
| | PT7_0057 | Putative citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (270 aa) |
| | PT7_0071 | Hypothetical protein. (451 aa) |
| | PT7_0076 | Hypothetical protein. (111 aa) |
| | PT7_0082 | Hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (163 aa) |
| | PT7_0104 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (503 aa) |
| | PT7_0106 | 3-carboxy-cis,cis-muconate cycloisomerase. (430 aa) |
| | PT7_0158 | Putative malonyl-CoA decarboxylase. (432 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa) |
| | cysG | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (465 aa) |
| | PT7_0351 | Putative lipoprotein. (130 aa) |
| | dapA-2 | Dihydrodipicolinate synthetase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) |
| | PT7_0393 | 2-dehydro-3-deoxy-phosphogluconate aldolase. (206 aa) |
| | PT7_0408 | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (865 aa) |
| | PT7_0413 | Aconitate hydratase. (864 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (300 aa) |
| | PT7_0476 | Threonine synthase. (469 aa) |
| | PT7_0607 | Hypothetical protein. (409 aa) |
| | PT7_0645 | Putative carboxynorspermide decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (368 aa) |
| | PT7_0656 | HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (298 aa) |
| | PT7_0668 | Acyl dehydratase. (153 aa) |
| | PT7_0670 | Hypothetical protein. (154 aa) |
| | PT7_0673 | Glucarate dehydratase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (422 aa) |
| | PT7_0675 | Carbonic anhydrase. (224 aa) |
| | PT7_0714 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (401 aa) |
| | PT7_0799 | Methylglyoxal synthase. (295 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (637 aa) |
| | PT7_0956 | Dihydrodipicolinate synthase; Belongs to the DapA family. (298 aa) |
| | PT7_0974 | Adenylate/guanylate cyclase. (1188 aa) |
| | argH | Argininosuccinate lyase. (472 aa) |
| | ubiC | Hypothetical protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (198 aa) |
| | fabZ | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa) |
| | mltG | Exported protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (338 aa) |
| | PT7_1124 | Carbonic anhydrase. (249 aa) |
| | fumC | 3-carboxy-cis,cis-muconate cycloisomerase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | PT7_1200 | Hypothetical protein. (450 aa) |
| | PT7_1252 | Hypothetical protein. (451 aa) |
| | PT7_1257 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (461 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (352 aa) |
| | PT7_1328 | Hypothetical protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (290 aa) |
| | PT7_1342 | Putative uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (271 aa) |
| | PT7_1408 | Mandelate racemase/muconate lactonizing protein. (396 aa) |
| | PT7_1448 | Isocitrate lyase. (441 aa) |
| | PT7_1458 | enoyl-CoA hydratase. (261 aa) |
| | PT7_1490 | P-protein. (361 aa) |
| | PT7_1527 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (458 aa) |
| | ectC | L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (131 aa) |
| | PT7_1542 | Diaminobutyrate--pyruvate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa) |
| | PT7_1563 | Putative carbonic anhydrase. (213 aa) |
| | PT7_1584 | Hypothetical protein. (157 aa) |
| | PT7_1604 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (541 aa) |
| | PT7_1618 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (303 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (282 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (354 aa) |
| | nth | A/G-specific adenine glycosylase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (210 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) |
| | PT7_1833 | Cytochrome c biogenesis protein, transmembrane region. (205 aa) |
| | PT7_1874 | Hypothetical protein. (3698 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (223 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (377 aa) |
| | PT7_1955 | Putative aldolase. (210 aa) |
| | PT7_2006 | Serine/threonine dehydratase. (322 aa) |
| | PT7_2026 | Aminodeoxychorismate synthase. (384 aa) |
| | PT7_2031 | Multidrug efflux-associated protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (216 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (393 aa) |
| | PT7_2046 | Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | PT7_2057 | Lytic transglycosylase. (294 aa) |
| | ubiD | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (514 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (165 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (360 aa) |
| | PT7_2125 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (258 aa) |
| | PT7_2157 | Orn/Arg/Lys decarboxylase. (753 aa) |
| | PT7_2167 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (594 aa) |
| | PT7_2188 | hydroxymethylglutaryl-CoA lyase. (312 aa) |
| | PT7_2255 | Glutathione-dependent formaldehyde-activating, GFA. (162 aa) |
| | PT7_2268 | Hypothetical protein. (206 aa) |
| | PT7_2272 | Hypothetical protein. (345 aa) |
| | PT7_2277 | enoyl-CoA hydratase. (267 aa) |
| | PT7_2284 | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. (290 aa) |
| | ectC-2 | L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (127 aa) |
| | leuD-2 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (215 aa) |
| | PT7_2317 | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | PT7_2343 | Hypothetical protein. (1167 aa) |
| | PT7_2345 | Hypothetical protein. (212 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (561 aa) |
| | PT7_2413 | L-Alanine-Dl-Glutamate Epimerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (412 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (358 aa) |
| | PT7_2445 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (119 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (190 aa) |
| | PT7_2529 | Membrane-bound lytic murein transglycosylase. (429 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (506 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | PT7_2568 | hydroxymethylglutaryl-CoA lyase. (302 aa) |
| | PT7_2612 | Aconitate hydratase. (937 aa) |
| | PT7_2616 | Hypothetical protein; Belongs to the D-glutamate cyclase family. (270 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (579 aa) |
| | PT7_2642 | Hypothetical protein. (460 aa) |
| | PT7_2649 | Hypothetical protein. (224 aa) |
| | PT7_2659 | Alanine racemase-like protein. (388 aa) |
| | PT7_2667 | Acyl dehydratase. (147 aa) |
| | PT7_2676 | MaoC-like dehydratase. (281 aa) |
| | PT7_2678 | Hypothetical protein. (133 aa) |
| | PT7_2717 | Hypothetical protein. (159 aa) |
| | PT7_2813 | Putative hydratase. (263 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | PT7_2859 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (337 aa) |
| | PT7_2884 | 3-hydroxyacyl-CoA dehydrogenase. (654 aa) |
| | PT7_2967 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (581 aa) |
| | PT7_2996 | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. (256 aa) |
| | PT7_2997 | Ureidoglycolate hydrolase. (167 aa) |
| | PT7_2998 | Hypothetical protein. (175 aa) |
| | PT7_3007 | Pterin-4-alpha-carbinolamine dehydratase. (95 aa) |
| | PT7_3035 | Putative allophanate hydrolase. (73 aa) |
| | PT7_3102 | HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (255 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (267 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | PT7_3158 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (340 aa) |
| | gmd | NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (346 aa) |
| | PT7_3189 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (357 aa) |
| | PT7_3203 | Hypothetical protein. (224 aa) |
| | PT7_3228 | Fatty oxidation complex, alpha subunit; Belongs to the enoyl-CoA hydratase/isomerase family. (696 aa) |
| | PT7_3301 | 2-methylisocitrate lyase. (287 aa) |
| | rlpA | Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (327 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (502 aa) |
| | PT7_3388 | Pyruvate carboxyltransferase. (311 aa) |
| | PT7_3419 | Mandelate racemase/muconate lactonizing protein. (396 aa) |
| | PT7_3445 | Hypothetical protein. (132 aa) |
| | PT7_3450 | Mandelate racemase/muconate lactonizing protein. (388 aa) |
| | PT7_3454 | Mandelate racemase/muconate lactonizing protein. (294 aa) |
| | PT7_3464 | enoyl-CoA hydratase. (264 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (950 aa) |
| | PT7_3492 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (283 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | PT7_3548 | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase. (289 aa) |
| | PT7_3558 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (580 aa) |
| | PT7_3565 | HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (267 aa) |
| | PT7_3587 | Hypothetical protein. (78 aa) |
| | PT7_3600 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (304 aa) |
| | PT7_3605 | Galactarate dehydratase. (520 aa) |
| | PT7_3610 | Aminocarboxymuconate-semialdehyde decarboxylase. (333 aa) |
| | PT7_3618 | O-acetylhomoserine aminocarboxypropyltransferase. (425 aa) |
| | ribB | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (399 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (271 aa) |
