(22 nodes) Lysine degradation network (Pusillimonas sp. T77)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PT7_0052	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	PT7_0430	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (398 aa)
	PT7_0431	Dihydrolipoamide dehydrogenase. (475 aa)
	PT7_0453	Succinic semialdehyde dehydrogenase. (479 aa)
	PT7_0495	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	PT7_0839	Dihydrolipoamide dehydrogenase. (471 aa)
	PT7_0998	Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	PT7_1009	Mercuric ion reductase. (479 aa)
	PT7_1018	Dihydrolipoamide dehydrogenase. (581 aa)
	PT7_1266	Malate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (350 aa)
	PT7_1592	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
	PT7_2039	glutaryl-CoA dehydrogenase. (397 aa)
	PT7_2226	Putative NAD-dependent aldehyde dehydrogenase. (490 aa)
	PT7_2442	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	PT7_2789	Dihydrolipoamide dehydrogenase. (463 aa)
	PT7_2882	Aldehyde dehydrogenase family protein. (475 aa)
	PT7_2883	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
	PT7_2884	3-hydroxyacyl-CoA dehydrogenase. (654 aa)
	PT7_3027	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	PT7_3042	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
	PT7_3258	Class IV aminotransferase. (287 aa)
	PT7_3457	Succinate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)

Your Current Organism:

Pusillimonas sp. T77

NCBI taxonomy Id: 1007105
Other names: P. sp. T7-7, Pusillimonas sp. T7-7

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
PT7_0052	PT7_0495	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.584
PT7_0052	PT7_0998	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.584
PT7_0052	PT7_2039	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	glutaryl-CoA dehydrogenase.	0.944
PT7_0052	PT7_2442	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.913
PT7_0052	PT7_2883	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.584
PT7_0052	PT7_2884	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.931
PT7_0052	PT7_3027	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.584
PT7_0430	PT7_0431	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.995
PT7_0430	PT7_0495	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.814
PT7_0430	PT7_0839	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.991
PT7_0430	PT7_0998	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.814
PT7_0430	PT7_1009	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Mercuric ion reductase.	0.974
PT7_0430	PT7_1018	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.978
PT7_0430	PT7_2039	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	glutaryl-CoA dehydrogenase.	0.911
PT7_0430	PT7_2789	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.987
PT7_0430	PT7_2883	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.814
PT7_0430	PT7_3027	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.814
PT7_0431	PT7_0430	Dihydrolipoamide dehydrogenase.	Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.995
PT7_0431	PT7_0839	Dihydrolipoamide dehydrogenase.	Dihydrolipoamide dehydrogenase.	0.913
PT7_0431	PT7_1009	Dihydrolipoamide dehydrogenase.	Mercuric ion reductase.	0.923