STRINGSTRING
lpxC lpxC PT7_0049 PT7_0049 lpxH lpxH kdkA kdkA PT7_0510 PT7_0510 PT7_0513 PT7_0513 kdsB kdsB lpxK lpxK PT7_0727 PT7_0727 lpxD lpxD lpxA lpxA lpxB lpxB hldD hldD PT7_1481 PT7_1481 kdsA kdsA PT7_1972 PT7_1972 PT7_2554 PT7_2554 PT7_2555 PT7_2555 PT7_3159 PT7_3159 PT7_3238 PT7_3238 PT7_3240 PT7_3240 gmhA gmhA PT7_3345 PT7_3345 PT7_3346 PT7_3346 PT7_3387 PT7_3387
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (307 aa)
PT7_0049Polysaccharide synthesis phosphatase. (182 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
kdkA3-deoxy-D-manno-octulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (238 aa)
PT7_0510Lipopolysaccharide core biosynthesis glycosyl protein. (383 aa)
PT7_0513ADP-heptose--LPS heptosyltransferase II. (318 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (254 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (359 aa)
PT7_0727Lipid A biosynthesis lauroyl acyltransferase. (326 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (361 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N-acetylglucos amine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (264 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (415 aa)
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (331 aa)
PT7_1481D-beta-d-heptose 7-phosphate kinase. (309 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (280 aa)
PT7_1972Putative lipoprotein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family. (179 aa)
PT7_2554Lipid A biosynthesis lauroyl acyltransferase. (283 aa)
PT7_2555Lipid A biosynthesis lauroyl acyltransferase. (296 aa)
PT7_3159Hypothetical protein. (407 aa)
PT7_3238Lipopolysaccharide heptosyltransferase-1. (332 aa)
PT7_32403-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (444 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (191 aa)
PT7_3345Hydrolase. (199 aa)
PT7_3346Hypothetical protein; Belongs to the SIS family. GutQ/KpsF subfamily. (329 aa)
PT7_3387Putative cytidylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (160 aa)
Your Current Organism:
Pusillimonas sp. T77
NCBI taxonomy Id: 1007105
Other names: P. sp. T7-7, Pusillimonas sp. T7-7
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