STRINGSTRING
secA secA PT7_0126 PT7_0126 PT7_0132 PT7_0132 PT7_0133 PT7_0133 PT7_0134 PT7_0134 PT7_0135 PT7_0135 PT7_0218 PT7_0218 PT7_0398 PT7_0398 PT7_0399 PT7_0399 PT7_0400 PT7_0400 PT7_0603 PT7_0603 PT7_0707 PT7_0707 PT7_0708 PT7_0708 PT7_0709 PT7_0709 PT7_0710 PT7_0710 PT7_0711 PT7_0711 flhD flhD flhC flhC PT7_0808 PT7_0808 PT7_0809 PT7_0809 PT7_0810 PT7_0810 potA-2 potA-2 PT7_1006 PT7_1006 PT7_1047 PT7_1047 PT7_1172 PT7_1172 PT7_1173 PT7_1173 PT7_1174 PT7_1174 PT7_1175 PT7_1175 PT7_1176 PT7_1176 PT7_1183 PT7_1183 PT7_1302 PT7_1302 PT7_1306 PT7_1306 PT7_1307 PT7_1307 PT7_1308 PT7_1308 PT7_1309 PT7_1309 PT7_1310 PT7_1310 PT7_1311 PT7_1311 hfq hfq ribA ribA PT7_1503 PT7_1503 PT7_1504 PT7_1504 PT7_1505 PT7_1505 PT7_1506 PT7_1506 PT7_1535 PT7_1535 PT7_1589 PT7_1589 PT7_1594 PT7_1594 PT7_1596 PT7_1596 PT7_1672 PT7_1672 PT7_1723 PT7_1723 PT7_1724 PT7_1724 PT7_1725 PT7_1725 PT7_1726 PT7_1726 PT7_1727 PT7_1727 PT7_1729 PT7_1729 PT7_1730 PT7_1730 PT7_1731 PT7_1731 PT7_1732 PT7_1732 PT7_1848 PT7_1848 PT7_1874 PT7_1874 PT7_1896 PT7_1896 PT7_1897 PT7_1897 PT7_1898 PT7_1898 PT7_1899 PT7_1899 PT7_1900 PT7_1900 PT7_1963 PT7_1963 PT7_1964 PT7_1964 PT7_1965 PT7_1965 PT7_1966 PT7_1966 yajC yajC ffh ffh trpE trpE PT7_2534 PT7_2534 PT7_2578 PT7_2578 PT7_2579 PT7_2579 PT7_2580 PT7_2580 PT7_2581 PT7_2581 PT7_2582 PT7_2582 PT7_2583 PT7_2583 PT7_2584 PT7_2584 PT7_2634 PT7_2634 PT7_2635 PT7_2635 PT7_2637 PT7_2637 PT7_2638 PT7_2638 PT7_2639 PT7_2639 PT7_2762 PT7_2762 PT7_2794 PT7_2794 PT7_2795 PT7_2795 PT7_2796 PT7_2796 PT7_2797 PT7_2797 PT7_2798 PT7_2798 PT7_2805 PT7_2805 PT7_2806 PT7_2806 PT7_2807 PT7_2807 PT7_2808 PT7_2808 PT7_2816 PT7_2816 PT7_2817 PT7_2817 PT7_2818 PT7_2818 PT7_2819 PT7_2819 PT7_2820 PT7_2820 secY secY PT7_2885 PT7_2885 secE secE PT7_2929 PT7_2929 PT7_2930 PT7_2930 PT7_2931 PT7_2931 PT7_2932 PT7_2932 PT7_2933 PT7_2933 yidC yidC PT7_3079 PT7_3079 PT7_3091 PT7_3091 PT7_3092 PT7_3092 PT7_3093 PT7_3093 PT7_3095 PT7_3095 PT7_3264 PT7_3264 PT7_3265 PT7_3265 PT7_3266 PT7_3266 PT7_3267 PT7_3267 PT7_3283 PT7_3283 PT7_3284 PT7_3284 PT7_3285 PT7_3285 PT7_3286 PT7_3286 fur-2 fur-2 secB secB PT7_3543 PT7_3543 PT7_3591 PT7_3591 PT7_3594 PT7_3594 ftsY ftsY
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (912 aa)
PT7_0126ABC transporter substrate-binding protein. (403 aa)
PT7_0132Branched-chain amino acid-binding protein. (446 aa)
PT7_0133Putative permease component of branched-chain amino acid transport system; Belongs to the binding-protein-dependent transport system permease family. (626 aa)
PT7_0134Branched-chain amino acid ABC transporter ATP-binding protein. (259 aa)
PT7_0135ABC transporter ATP-binding protein. (248 aa)
PT7_0218Transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways. (97 aa)
PT7_0398Putative oligopeptide transport system permease protein. (325 aa)
PT7_0399Putative oligopeptide ABC-transporter permease. (485 aa)
PT7_0400Putative ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (579 aa)
PT7_0603ABC transporter, substrate-binding protein. (399 aa)
PT7_0707Amino acid ABC transporter. (385 aa)
PT7_0708Putative ABC transport protein, inner membrane component; Belongs to the binding-protein-dependent transport system permease family. (310 aa)
PT7_0709Putative ABC transport protein, ATP-binding component; Belongs to the binding-protein-dependent transport system permease family. (362 aa)
PT7_0710Putative ABC transport protein, ATP-binding component. (276 aa)
PT7_0711Putative branched-chain amino acid ABC transporter, ATP-binding protein. (244 aa)
flhDTranscriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (107 aa)
flhCTranscriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (204 aa)
PT7_0808Permease of ABC transporter. (286 aa)
PT7_0809Putative permease of ABC transporter. (414 aa)
PT7_0810Binding protein component of ABC transporter. (355 aa)
potA-2Polyamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (373 aa)
PT7_1006Outer membrane efflux protein. (510 aa)
PT7_1047Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor. (475 aa)
PT7_1172High-affinity branched-chain amino acid transport, ATP-binding protein. (233 aa)
PT7_1173Leucine/isoleucine/valine transporter ATP-binding subunit. (255 aa)
PT7_1174Leucine/isoleucine/valine transporter permease subunit; Belongs to the binding-protein-dependent transport system permease family. (408 aa)
PT7_1175High-affinity branched-chain amino acid transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family. (308 aa)
PT7_1176leu/Ile/val-binding protein precursor. (373 aa)
PT7_1183leu/Ile/val-binding protein precursor. (374 aa)
PT7_1302ABC-transporter, substrate binding protein. (401 aa)
PT7_1306Putative AMP-binding enzyme. (606 aa)
PT7_1307ABC transporter protein. (287 aa)
PT7_1308Putative amino acids binding protein. (396 aa)
PT7_1309High-affinity branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. (345 aa)
PT7_1310High-affinity branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. (293 aa)
PT7_1311ABC transporter protein. (276 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (78 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (224 aa)
PT7_1503ABC transporter protein. (234 aa)
PT7_1504Putative branched-chain amino acid transport system protein; Belongs to the binding-protein-dependent transport system permease family. (612 aa)
PT7_1505Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (291 aa)
PT7_1506ABC transporter, substrate-binding protein. (448 aa)
PT7_1535Phospho-2-dehydro-3-deoxyheptonate aldolase,Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (364 aa)
PT7_1589Extracellular ligand-binding receptor. (433 aa)
PT7_1594ABC transporter protein. (246 aa)
PT7_1596Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (301 aa)
PT7_1672Putative ABC transport protein, substrate-binding component. (403 aa)
PT7_1723HAAT family protein. (263 aa)
PT7_1724ABC transporter ATP-binding protein. (236 aa)
PT7_1725ABC-transporter, substrate binding protein. (403 aa)
PT7_1726ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (295 aa)
PT7_1727Putative branched-chain amino acid transport permease; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
PT7_1729Putative branched-chain amino acid transport system protein. (258 aa)
PT7_1730Putative branched-chain amino acid transport system protein; Belongs to the binding-protein-dependent transport system permease family. (617 aa)
PT7_1731Branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. (345 aa)
PT7_1732Hypothetical protein. (389 aa)
PT7_1848Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (160 aa)
PT7_1874Hypothetical protein. (3698 aa)
PT7_1896ABC transporter ATP-binding protein. (233 aa)
PT7_1897Branched-chain amino acid ABC transporter ATP-binding protein. (256 aa)
PT7_1898Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (314 aa)
PT7_1899Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (285 aa)
PT7_1900Extracellular ligand-binding receptor. (406 aa)
PT7_1963ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (569 aa)
PT7_1964ABC transporter permease. (277 aa)
PT7_1965ABC peptide transporter, inner membrane subunit. (329 aa)
PT7_1966Peptide/opine/nickel ABC transporter periplasmic ligand-binding protein. (541 aa)
yajCPutative secreted protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (114 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (471 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (506 aa)
PT7_2534Anthranilate synthase component II. (187 aa)
PT7_2578High-affinity branched-chain amino acid ABC transporter, ATP-binding protein. (276 aa)
PT7_2579Putative branched-chain amino acid transport system substrate-binding protein. (441 aa)
PT7_2580Putative branched-chain amino acid transport system permease; Belongs to the binding-protein-dependent transport system permease family. (354 aa)
PT7_2581Putative branched-chain amino acid transport system permease; Belongs to the binding-protein-dependent transport system permease family. (309 aa)
PT7_2582High-affinity branched-chain amino acid transporter, ATP-binding protein. (265 aa)
PT7_2583Putative AMP-binding enzyme. (658 aa)
PT7_2584Cyclic nucleotide-binding regulatory protein. (224 aa)
PT7_2634ABC transporter ATP-binding protein. (242 aa)
PT7_2635ABC transporter ATP-binding protein. (250 aa)
PT7_2637ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (327 aa)
PT7_2638ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (300 aa)
PT7_2639ABC transporter substrate-binding protein. (425 aa)
PT7_2762Putative Leu/Ile/Val-binding protein. (385 aa)
PT7_2794Putative branched-chain amino acid ABC transporter, ATP-binding protein. (241 aa)
PT7_2795Branched-chain amino acid ABC transporter ATP-binding protein. (259 aa)
PT7_2796Putative permease component of branched-chain amino acid transport system; Belongs to the binding-protein-dependent transport system permease family. (410 aa)
PT7_2797Branched chain amino acid ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family. (313 aa)
PT7_2798Branched-chain amino acid ABC transporter. (412 aa)
PT7_2805Branched-chain amino acid ABC transporter, periplasmic binding protein. (399 aa)
PT7_2806Putative ABC transport protein, inner membrane component; Belongs to the binding-protein-dependent transport system permease family. (288 aa)
PT7_2807Putative branched-chain amino acid transport system protein; Belongs to the binding-protein-dependent transport system permease family. (593 aa)
PT7_2808Branched-chain amino acid ABC transporter, ATP-binding protein. (234 aa)
PT7_2816Putative binding-protein-dependent transport protein. (371 aa)
PT7_2817High-affinity branched-chain amino acid transport ATP-binding protein. (237 aa)
PT7_2818High-affinity branched-chain amino acid transport ATP-binding protein. (253 aa)
PT7_2819Putative branched-chain amino acid transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. (309 aa)
PT7_2820Branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. (291 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (441 aa)
PT7_2885acyl-CoA synthetase, long-chain-fatty-acid--CoA ligase. (552 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (126 aa)
PT7_2929ABC transporter ATP-binding protein. (237 aa)
PT7_2930ABC transporter ATP-binding protein. (247 aa)
PT7_2931Putative branched-chain amino acid transport permease; Belongs to the binding-protein-dependent transport system permease family. (337 aa)
PT7_2932Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (306 aa)
PT7_2933Extracellular ligand-binding receptor. (400 aa)
yidCPutative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (565 aa)
PT7_3079Putative extracellular solute-binding protein. (529 aa)
PT7_3091ABC transporter substrate-binding protein. (405 aa)
PT7_3092Putative branched-chain amino acid transport permease; Belongs to the binding-protein-dependent transport system permease family. (296 aa)
PT7_3093Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
PT7_3095Putative branched-chain amino acid transport ATP-binding ABC transporter. (244 aa)
PT7_3264Putative extracellular solute-binding protein. (538 aa)
PT7_3265ABC transporter, permease protein. (325 aa)
PT7_3266Putative ABC-transporter permease. (315 aa)
PT7_3267Putative oligopeptide transport ATP-binding protein; Belongs to the ABC transporter superfamily. (327 aa)
PT7_3283Putative extracellular solute-binding protein. (527 aa)
PT7_3284Putative transport system permease protein. (308 aa)
PT7_3285Putative ABC-transporter permease. (283 aa)
PT7_3286Putative transport system ATP-binding protein; Belongs to the ABC transporter superfamily. (327 aa)
fur-2Putative regulatory protein; Belongs to the Fur family. (156 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (174 aa)
PT7_3543Putative riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (374 aa)
PT7_3591ABC-type branched-chain amino acid transport systems periplasmic component-like protein. (421 aa)
PT7_3594ABC transporter, substrate-binding protein. (404 aa)
ftsYCell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (378 aa)
Your Current Organism:
Pusillimonas sp. T77
NCBI taxonomy Id: 1007105
Other names: P. sp. T7-7, Pusillimonas sp. T7-7
Server load: low (18%) [HD]