node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | TASI_1223 | TASI_1222 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
carA | pyrB | TASI_1223 | TASI_1392 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | TASI_1223 | TASI_0398 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.489 |
carA | pyrD | TASI_1223 | TASI_1251 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.910 |
carA | pyrE | TASI_1223 | TASI_1413 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.899 |
carA | pyrF | TASI_1223 | TASI_0354 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.907 |
carA | upp | TASI_1223 | TASI_1336 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.445 |
carB | carA | TASI_1222 | TASI_1223 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
carB | pyrB | TASI_1222 | TASI_1392 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | TASI_1222 | TASI_0398 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.587 |
carB | pyrD | TASI_1222 | TASI_1251 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.938 |
carB | pyrE | TASI_1222 | TASI_1413 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.925 |
carB | pyrF | TASI_1222 | TASI_0354 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.918 |
carB | pyrG | TASI_1222 | TASI_1052 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.468 |
ndk | pyrG | TASI_0756 | TASI_1052 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.927 |
ndk | pyrH | TASI_0756 | TASI_0887 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.936 |
pyrB | carA | TASI_1392 | TASI_1223 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
pyrB | carB | TASI_1392 | TASI_1222 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
pyrB | pyrC | TASI_1392 | TASI_0398 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.972 |
pyrB | pyrD | TASI_1392 | TASI_1251 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.932 |