(33 nodes) Ligase activity, forming carbon-nitrogen bonds network (Taylorella asinigenitalis)

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Your Input:
	purC	Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (296 aa)
	TASI_0053	Biotin-protein ligase. (291 aa)
	gatB	Aspartyl-tRNA(Asn) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (484 aa)
	gatA	Aspartyl-tRNA(Asn) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (503 aa)
	gatC	Aspartyl-tRNA(Asn) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (102 aa)
	panC	Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
	queC	Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (222 aa)
	bioD	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (215 aa)
	pncB	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (414 aa)
	purD	Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (428 aa)
	tilS	tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (372 aa)
	TASI_0714	Transamidase GatB domain protein. (138 aa)
	purL	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1333 aa)
	guaA	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (532 aa)
	purA	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
	TASI_0834	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase. (338 aa)
	TASI_0835	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (212 aa)
	TASI_0899	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (426 aa)
	argG	Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)
	pyrG	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (548 aa)
	TASI_1093	Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (389 aa)
	TASI_1108	Glutamine synthetase type I. (470 aa)
	carB	Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1081 aa)
	carA	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (383 aa)
	purM	Phosphoribosylformylglycinamidine cyclo-ligase. (351 aa)
	ddl	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (312 aa)
	murC	UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (472 aa)
	murD	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (481 aa)
	murF	Murein precusor biosynthesis bifunctional protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (910 aa)
	purK	Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (385 aa)
	TASI_1384	Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
	TASI_1386	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase. (443 aa)
	TASI_1401	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (189 aa)

Your Current Organism:

Taylorella asinigenitalis

NCBI taxonomy Id: 1008459
Other names: T. asinigenitalis MCE3, Taylorella asinigenitalis MCE3, Taylorella asinigenitalis str. MCE3, Taylorella asinigenitalis strain MCE3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TASI_0053	TASI_0834	TASI_0053	TASI_0834	Biotin-protein ligase.	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	0.474
TASI_0053	TASI_0835	TASI_0053	TASI_0835	Biotin-protein ligase.	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.474
TASI_0053	TASI_1384	TASI_0053	TASI_1384	Biotin-protein ligase.	Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.908
TASI_0053	guaA	TASI_0053	TASI_0720	Biotin-protein ligase.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.503
TASI_0834	TASI_0053	TASI_0834	TASI_0053	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Biotin-protein ligase.	0.474
TASI_0834	TASI_0835	TASI_0834	TASI_0835	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.996
TASI_0834	TASI_0899	TASI_0834	TASI_0899	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	0.476
TASI_0834	TASI_1108	TASI_0834	TASI_1108	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Glutamine synthetase type I.	0.513
TASI_0834	bioD	TASI_0834	TASI_0284	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.433
TASI_0834	guaA	TASI_0834	TASI_0720	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.845
TASI_0834	murF	TASI_0834	TASI_1286	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Murein precusor biosynthesis bifunctional protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.557
TASI_0834	panC	TASI_0834	TASI_0189	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.	0.476
TASI_0834	pncB	TASI_0834	TASI_0525	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.	0.594
TASI_0834	purL	TASI_0834	TASI_0717	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.	0.836
TASI_0835	TASI_0053	TASI_0835	TASI_0053	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Biotin-protein ligase.	0.474
TASI_0835	TASI_0834	TASI_0835	TASI_0834	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	NAD synthetase; Glutamine amidotransferase chain of NAD synthetase.	0.996
TASI_0835	TASI_0899	TASI_0835	TASI_0899	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	0.476
TASI_0835	TASI_1108	TASI_0835	TASI_1108	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Glutamine synthetase type I.	0.513
TASI_0835	bioD	TASI_0835	TASI_0284	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.433
TASI_0835	guaA	TASI_0835	TASI_0720	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.845

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