STRINGSTRING
murG murG TASI_0057 TASI_0057 glmU glmU mrdA mrdA mrdB mrdB TASI_0229 TASI_0229 rlpA rlpA lptA lptA TASI_0390 TASI_0390 TASI_0632 TASI_0632 uppP uppP TASI_0708 TASI_0708 TASI_0716 TASI_0716 bamB bamB nagZ nagZ mltG mltG bamA bamA murJ murJ bamD bamD TASI_1151 TASI_1151 TASI_1168 TASI_1168 bamE bamE murB murB ddl ddl murC murC ftsW ftsW murD murD mraY mraY murF murF TASI_1287 TASI_1287 surA surA lptD lptD TASI_1301 TASI_1301 TASI_1386 TASI_1386 murA murA TASI_1472 TASI_1472
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (358 aa)
TASI_0057D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (430 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (460 aa)
mrdAPenicillin-binding protein 2 (PBP-2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (687 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (388 aa)
TASI_0229Membrane-bound lytic murein transglycosylase A precursor. (423 aa)
rlpARare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (161 aa)
lptAProtein yhbN precursor; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (206 aa)
TASI_0390O-antigen flippase Wzx. (426 aa)
TASI_0632LPS-assembly lipoprotein RlpB precursor; Rare lipoprotein B. (125 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (285 aa)
TASI_0708Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (267 aa)
TASI_0716Murein-DD-endopeptidase; Belongs to the peptidase S11 family. (366 aa)
bamBOuter membrane protein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (384 aa)
nagZBeta N-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (352 aa)
mltGProtein YceG like protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (342 aa)
bamAOuter membrane protein assembly factor YaeT precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (794 aa)
murJProposed peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (541 aa)
bamDLipoprotein assembly complex like-component; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (272 aa)
TASI_1151Outer membrane protein NlpB; Lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor. (442 aa)
TASI_1168Putative lipoprotein. (180 aa)
bamEOuter membrane lipoprotein SmpA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (139 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (338 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (312 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (472 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (400 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (481 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (389 aa)
murFMurein precusor biosynthesis bifunctional protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (910 aa)
TASI_1287Cell division protein FtsI (Peptidoglycan synthetase). (555 aa)
surASurvival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (498 aa)
lptDOuter membrane protein Imp; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (793 aa)
TASI_1301COG3178:phosphotransferase related to Ser/Thr protein kinases. (343 aa)
TASI_1386UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase. (443 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
TASI_1472Multimodular transpeptidase-transglycosylase. (822 aa)
Your Current Organism:
Taylorella asinigenitalis
NCBI taxonomy Id: 1008459
Other names: T. asinigenitalis MCE3, Taylorella asinigenitalis MCE3, Taylorella asinigenitalis str. MCE3, Taylorella asinigenitalis strain MCE3
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