Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TASI_0196 | TASI_0497 | TASI_0196 | TASI_0497 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.842 |
| TASI_0196 | TASI_0710 | TASI_0196 | TASI_0710 | Serine acetyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.995 |
| TASI_0196 | TASI_0970 | TASI_0196 | TASI_0970 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.837 |
| TASI_0196 | glyA | TASI_0196 | TASI_1367 | Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.838 |
| TASI_0196 | ilvA | TASI_0196 | TASI_0246 | Serine acetyltransferase. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.802 |
| TASI_0196 | thrB | TASI_0196 | TASI_0798 | Serine acetyltransferase. | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.825 |
| TASI_0228 | TASI_1328 | TASI_0228 | TASI_1328 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Transketolase; Belongs to the transketolase family. | 0.973 |
| TASI_0228 | eno | TASI_0228 | TASI_1050 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.403 |
| TASI_0228 | metK | TASI_0228 | TASI_1411 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.448 |
| TASI_0228 | pgk | TASI_0228 | TASI_1326 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.492 |
| TASI_0228 | prs | TASI_0228 | TASI_0335 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.407 |
| TASI_0228 | rpiA | TASI_0228 | TASI_0961 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.946 |
| TASI_0228 | tpiA | TASI_0228 | TASI_0409 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.476 |
| TASI_0322 | TASI_0606 | TASI_0322 | TASI_0606 | Putative epoxyalkane:coenzyme M transferase. | Chorismate mutase I; Prephenate dehydratase. | 0.535 |
| TASI_0322 | TASI_0710 | TASI_0322 | TASI_0710 | Putative epoxyalkane:coenzyme M transferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.843 |
| TASI_0322 | TASI_0826 | TASI_0322 | TASI_0826 | Putative epoxyalkane:coenzyme M transferase. | Aromatic-amino-acid aminotransferase. | 0.902 |
| TASI_0322 | TASI_0970 | TASI_0322 | TASI_0970 | Putative epoxyalkane:coenzyme M transferase. | Homoserine dehydrogenase. | 0.867 |
| TASI_0322 | glyA | TASI_0322 | TASI_1367 | Putative epoxyalkane:coenzyme M transferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.404 |
| TASI_0322 | ilvA | TASI_0322 | TASI_0246 | Putative epoxyalkane:coenzyme M transferase. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.823 |
| TASI_0322 | ilvC | TASI_0322 | TASI_1170 | Putative epoxyalkane:coenzyme M transferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.468 |
page 1 of 25