(52 nodes) Positive regulation of epithelial to mesenchymal transition network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ctnnb1	Catenin beta 1. (781 aa)
	Twist1	Twist-related protein 1. (206 aa)
	Tgfb3	Transforming growth factor beta-3. (412 aa)
	Foxc1	Forkhead box protein C1. (553 aa)
	LOC110307912	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase. (401 aa)
	Axin2	Axin 2. (840 aa)
	Col1a1	Collagen alpha-1(I) chain isoform X1. (1452 aa)
	Myocd	Myocardin isoform X1. (983 aa)
	Alx1	Cartilage homeoprotein 1. (326 aa)
	Hdac2	Histone deacetylase 1/2. (488 aa)
	Tgfb2	Transforming growth factor beta-2 isoform X1. (442 aa)
	Isl1	Insulin gene enhancer protein ISL-1 isoform X1. (349 aa)
	Fermt2	Fermitin family homolog 2 isoform X1. (680 aa)
	Bmp4	Bone morphogenetic protein 4. (408 aa)
	Loxl2	Lysyl oxidase-like protein 2/3/4. (776 aa)
	Rgcc	Regulator of cell cycle RGCC. (137 aa)
	Dab2	Disabled homolog 2. (766 aa)
	Emp2	Epithelial membrane protein 2. (172 aa)
	Ager	Advanced glycosylation end product-specific receptor isoform X1. (403 aa)
	Lrg1	Leucine-rich alpha-2-glycoprotein. (342 aa)
	Bambi	BMP and activin membrane-bound inhibitor homolog. (260 aa)
	Smad4	Mothers against decapentaplegic homolog 4. (551 aa)
	Smad2	Mothers against decapentaplegic homolog 2 isoform X1. (467 aa)
	Tcf7l2	Transcription factor 7 like 2. (606 aa)
	Notch1	Neurogenic locus notch homolog protein 1. (2531 aa)
	Olfm1	Noelin isoform X1. (485 aa)
	Eng	Endoglin isoform X1. (653 aa)
	Crb2	Protein crumbs homolog 2. (1282 aa)
	Acvr1	Activin receptor type-1. (509 aa)
	Mdk	Midkine isoform X1. (140 aa)
	Il1b	Interleukin 1 beta. (270 aa)
	Bmp2	Bone morphogenetic protein 2. (394 aa)
	Jag1	Protein jagged-1. (1218 aa)
	Snai1	Zinc finger protein SNAI1. (264 aa)
	Bmp7	Bone morphogenetic protein 7. (430 aa)
	Wwtr1	WW domain-containing transcription regulator protein 1 isoform X1. (452 aa)
	Lef1	Lymphoid enhancer-binding factor 1 isoform X1. (397 aa)
	Sdcbp	Syntenin-1 isoform X1. (299 aa)
	Glipr2	Golgi-associated plant pathogenesis-related protein 1. (154 aa)
	Tgfbr1	TGF-beta receptor type-1. (503 aa)
	Pdpn	Podoplanin isoform X1. (172 aa)
	Mtor	Serine/threonine-protein kinase mTOR. (2549 aa)
	Il6	Interleukin 6. (211 aa)
	Ezh2	[histone H3]-lysine27 N-trimethyltransferase EZH2. (732 aa)
	Tgfb1	Transforming growth factor beta-1. (390 aa)
	Tgfb1i1	Transforming growth factor beta-1-induced transcript 1 protein isoform X1. (461 aa)
	Tgfb1i1-2	Transforming growth factor beta 1 induced transcript 1. (350 aa)
	Zfp703	Zinc finger protein 703 isoform X1. (596 aa)
	Tbx20	T-box transcription factor TBX20 isoform X1. (445 aa)
	Bcl9l	B-cell CLL/lymphoma 9-like protein isoform X1. (1494 aa)
	Smad3	Mothers against decapentaplegic homolog 3. (425 aa)
	Tgfbr2	TGF-beta receptor type-2 isoform X1. (592 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acvr1	Bambi	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0045926	Activin receptor type-1.	BMP and activin membrane-bound inhibitor homolog.	0.967
Acvr1	Bmp2	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0054833	Activin receptor type-1.	Bone morphogenetic protein 2.	0.977
Acvr1	Bmp4	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0036330	Activin receptor type-1.	Bone morphogenetic protein 4.	0.989
Acvr1	Bmp7	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0056456	Activin receptor type-1.	Bone morphogenetic protein 7.	0.988
Acvr1	Ctnnb1	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0090603	Activin receptor type-1.	Catenin beta 1.	0.404
Acvr1	Eng	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0051171	Activin receptor type-1.	Endoglin isoform X1.	0.524
Acvr1	Smad2	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0047151	Activin receptor type-1.	Mothers against decapentaplegic homolog 2 isoform X1.	0.971
Acvr1	Smad3	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0088272	Activin receptor type-1.	Mothers against decapentaplegic homolog 3.	0.966
Acvr1	Smad4	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0047101	Activin receptor type-1.	Mothers against decapentaplegic homolog 4.	0.772
Acvr1	Tgfb1	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0078112	Activin receptor type-1.	Transforming growth factor beta-1.	0.664
Acvr1	Tgfb2	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0021818	Activin receptor type-1.	Transforming growth factor beta-2 isoform X1.	0.573
Acvr1	Tgfb3	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0032929	Activin receptor type-1.	Transforming growth factor beta-3.	0.707
Acvr1	Tgfbr1	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0062295	Activin receptor type-1.	TGF-beta receptor type-1.	0.837
Acvr1	Tgfbr2	MGP_CAROLIEiJ_P0051832	MGP_CAROLIEiJ_P0090480	Activin receptor type-1.	TGF-beta receptor type-2 isoform X1.	0.730
Axin2	Bmp4	MGP_CAROLIEiJ_P0030674	MGP_CAROLIEiJ_P0036330	Axin 2.	Bone morphogenetic protein 4.	0.502
Axin2	Ctnnb1	MGP_CAROLIEiJ_P0030674	MGP_CAROLIEiJ_P0090603	Axin 2.	Catenin beta 1.	0.995
Axin2	Jag1	MGP_CAROLIEiJ_P0030674	MGP_CAROLIEiJ_P0054888	Axin 2.	Protein jagged-1.	0.435
Axin2	Lef1	MGP_CAROLIEiJ_P0030674	MGP_CAROLIEiJ_P0060538	Axin 2.	Lymphoid enhancer-binding factor 1 isoform X1.	0.975
Axin2	Notch1	MGP_CAROLIEiJ_P0030674	MGP_CAROLIEiJ_P0050383	Axin 2.	Neurogenic locus notch homolog protein 1.	0.473
Axin2	Snai1	MGP_CAROLIEiJ_P0030674	MGP_CAROLIEiJ_P0056336	Axin 2.	Zinc finger protein SNAI1.	0.571