(62 nodes) Myofibril assembly network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Pdgfra	Platelet-derived growth factor receptor alpha isoform X1. (1089 aa)
	Wdr1	WD repeat-containing protein 1 isoform X1. (606 aa)
	Cavin4	Muscle-related coiled-coil protein. (369 aa)
	Tmod1	Tropomodulin-1. (359 aa)
	Myoz2	Myozenin-2. (264 aa)
	Casq2	Calsequestrin 2. (415 aa)
	Tmod4	Tropomodulin-4 isoform X1. (345 aa)
	Neurl2	Neuralized-like protein 2 isoform X1. (285 aa)
	Myl9	Myosin regulatory light polypeptide 9. (172 aa)
	Capn3	Calpain-3 isoform X1. (821 aa)
	Actc1	Actin, alpha cardiac muscle 1. (377 aa)
	Mybpc3	Myosin-binding protein C, cardiac-type isoform X1. (1284 aa)
	Ttn	Titin. (32000 aa)
	Klhl41	Kelch repeat and BTB domain-containing protein 5/10. (606 aa)
	MGP_CAROLIEiJ_P0051763	annotation not available (1189 aa)
	Nebl	Nebulette isoform X1. (1014 aa)
	Nrap	Nebulin-related-anchoring protein isoform X1. (1728 aa)
	Pgm5	Phosphoglucomutase-like protein 5. (567 aa)
	Pdgfrb	Platelet-derived growth factor receptor beta. (1111 aa)
	Fhod3	FH1/FH2 domain-containing protein 3 isoform X1. (1579 aa)
	Srf	Serum response factor. (504 aa)
	Nkx2-5	Homeobox protein Nkx-2.5. (318 aa)
	Myh11	Myosin heavy chain 9/10/11/14. (1979 aa)
	Krt8	Keratin, type II cytoskeletal 8. (510 aa)
	Myh7	Myosin heavy chain 6/7. (1935 aa)
	Myh6	Myosin heavy chain 6/7. (1954 aa)
	Ldb3	LIM domain binding 3. (723 aa)
	Synpo2l	Synaptopodin 2-like protein isoform X1. (978 aa)
	Myoz1	Myozenin-1. (296 aa)
	Actn2	Actinin alpha 2/3. (833 aa)
	Six4	Homeobox protein SIX4. (775 aa)
	Cfl2	Cofilin-2 isoform X1. (166 aa)
	Prkar1a	CAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
	Krt19	Keratin, type I cytoskeletal 19. (403 aa)
	Tcap	Telethonin. (167 aa)
	Myh10	Myosin heavy chain 9/10/11/14. (1965 aa)
	Flii	Protein flightless-1 homolog isoform X1. (1271 aa)
	Csrp2	Cysteine and glycine-rich protein 2. (193 aa)
	Mypn	Myopalladin. (1316 aa)
	Prox1	Prospero homeobox protein 1 isoform X1. (737 aa)
	Casq1	Calsequestrin 1. (407 aa)
	Tnnt2	Troponin T, cardiac muscle isoform X1. (302 aa)
	Csrp1	Cysteine and glycine-rich protein 1. (193 aa)
	Lmod1	Leiomodin-1. (596 aa)
	Cflar	CASP8 and FADD-like apoptosis regulator. (481 aa)
	Xirp1	Xin actin-binding repeat-containing protein 1. (1132 aa)
	Tmod2	Tropomodulin-2. (351 aa)
	Tmod3	Tropomodulin-3. (352 aa)
	Tpm1	Tropomyosin alpha-1 chain isoform X1. (326 aa)
	Itgb1	Integrin beta 1. (798 aa)
	Acta1	Actin, alpha skeletal muscle isoform X1. (377 aa)
	Mylk3	Myosin light chain kinase 3 isoform X1. (795 aa)
	MGP_CAROLIEiJ_P0083880	annotation not available (1302 aa)
	Adprhl1	Protein ADP-ribosylarginine hydrolase-like protein 1. (1640 aa)
	Tnnt3	Troponin T, fast skeletal muscle isoform X1. (272 aa)
	Mef2a	Myocyte enhancer factor 2A. (498 aa)
	Csrp3	Cysteine and glycine-rich protein 3. (194 aa)
	Tnnt1	Troponin T1, slow skeletal type. (273 aa)
	Bmp10	Bone morphogenetic protein 10. (421 aa)
	Flnc	Filamin-C isoform X1. (2726 aa)
	Lmod2	Leiomodin-2 isoform X1. (550 aa)
	Myl2	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acta1	Actn2	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0033675	Actin, alpha skeletal muscle isoform X1.	Actinin alpha 2/3.	0.807
Acta1	Cfl2	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0032268	Actin, alpha skeletal muscle isoform X1.	Cofilin-2 isoform X1.	0.498
Acta1	Csrp3	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0079756	Actin, alpha skeletal muscle isoform X1.	Cysteine and glycine-rich protein 3.	0.541
Acta1	Klhl41	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0052123	Actin, alpha skeletal muscle isoform X1.	Kelch repeat and BTB domain-containing protein 5/10.	0.458
Acta1	Lmod1	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0020033	Actin, alpha skeletal muscle isoform X1.	Leiomodin-1.	0.592
Acta1	MGP_CAROLIEiJ_P0051763	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0051763	Actin, alpha skeletal muscle isoform X1.	annotation not available	0.437
Acta1	MGP_CAROLIEiJ_P0083880	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0083880	Actin, alpha skeletal muscle isoform X1.	annotation not available	0.454
Acta1	Mybpc3	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0053006	Actin, alpha skeletal muscle isoform X1.	Myosin-binding protein C, cardiac-type isoform X1.	0.506
Acta1	Myh10	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0027403	Actin, alpha skeletal muscle isoform X1.	Myosin heavy chain 9/10/11/14.	0.442
Acta1	Myh11	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0040478	Actin, alpha skeletal muscle isoform X1.	Myosin heavy chain 9/10/11/14.	0.790
Acta1	Myh6	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0036744	Actin, alpha skeletal muscle isoform X1.	Myosin heavy chain 6/7.	0.734
Acta1	Myh7	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0036750	Actin, alpha skeletal muscle isoform X1.	Myosin heavy chain 6/7.	0.740
Acta1	Myl2	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0070515	Actin, alpha skeletal muscle isoform X1.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform.	0.581
Acta1	Myl9	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0055710	Actin, alpha skeletal muscle isoform X1.	Myosin regulatory light polypeptide 9.	0.646
Acta1	Myoz1	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0035747	Actin, alpha skeletal muscle isoform X1.	Myozenin-1.	0.653
Acta1	Mypn	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0023173	Actin, alpha skeletal muscle isoform X1.	Myopalladin.	0.533
Acta1	Pdgfra	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0068689	Actin, alpha skeletal muscle isoform X1.	Platelet-derived growth factor receptor alpha isoform X1.	0.438
Acta1	Pdgfrb	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0046851	Actin, alpha skeletal muscle isoform X1.	Platelet-derived growth factor receptor beta.	0.458
Acta1	Srf	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0045025	Actin, alpha skeletal muscle isoform X1.	Serum response factor.	0.441
Acta1	Tmod1	MGP_CAROLIEiJ_P0086492	MGP_CAROLIEiJ_P0062231	Actin, alpha skeletal muscle isoform X1.	Tropomodulin-1.	0.459