(77 nodes) Histone lysine methylation network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mllt6	Protein AF-17 isoform X1. (1111 aa)
	Rbbp5	Retinoblastoma-binding protein 5 isoform X1. (538 aa)
	Smyd3	[histone H3]-lysine4/36 N-trimethyltransferase SMYD. (428 aa)
	Smyd2	[histone H3]-lysine4/36 N-trimethyltransferase SMYD. (433 aa)
	Hdac2	Histone deacetylase 1/2. (488 aa)
	Bend3	BEN domain-containing protein 3. (825 aa)
	Izumo4	Izumo sperm-egg fusion protein 4 isoform X1. (227 aa)
	Dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1. (1540 aa)
	Nfyb	Nuclear transcription factor Y subunit beta. (207 aa)
	Pwp1	Periodic tryptophan protein 1 homolog. (501 aa)
	Pno1	RNA-binding protein PNO1. (248 aa)
	Ezh1	Histone-lysine N-methyltransferase EZH1 isoform X1. (750 aa)
	Asxl2	Additional sex combs like 2, transcriptional regulator. (1407 aa)
	Arid4a	AT-rich interactive domain-containing protein 4A. (1260 aa)
	Setd3	Histone-lysine N-methyltransferase setd3 isoform X1. (290 aa)
	Arid4b	AT-rich interactive domain-containing protein 4B. (1314 aa)
	H1f3	Histone H1.3. (221 aa)
	H1f4	Histone H1.4. (219 aa)
	H1f2	Histone H1.2. (212 aa)
	Dydc2	DPY30 domain-containing protein 2. (139 aa)
	Dydc1	DPY30 domain-containing protein 1 isoform X1. (177 aa)
	Phf11	PHD finger protein 11. (315 aa)
	Setdb2	Histone-lysine N-methyltransferase SETDB2 isoform X1. (713 aa)
	Kmt2d	[histone H3]-lysine4 N-trimethyltransferase MLL2. (5590 aa)
	Wdr5b	WD repeat-containing protein 5B. (328 aa)
	N6amt1	Release factor glutamine methyltransferase. (214 aa)
	MGP_CAROLIEiJ_P0042831	[histone H3]-lysine4 N-trimethyltransferase PRDM7/9. (283 aa)
	Ehmt2	Histone-lysine N-methyltransferase EHMT2 isoform X1. (1263 aa)
	Nfya	Nuclear transcription factor Y subunit alpha isoform X1. (347 aa)
	Cxxc1	CXXC-type zinc finger protein 1 isoform X1. (660 aa)
	Setbp1	SET-binding protein. (1585 aa)
	Kmt5b	[histone H4]-N-methyl-L-lysine20 N-methyltransferase. (882 aa)
	Men1	Menin isoform X1. (617 aa)
	Trmt112	Multifunctional methyltransferase subunit TRM112-like protein. (125 aa)
	Suv39h2	[histone H3]-lysine9 N-trimethyltransferase SUV39H. (477 aa)
	Ehmt1	Histone-lysine N-methyltransferase EHMT1 isoform X1. (1310 aa)
	Wdr5	WD repeat-containing protein 5. (334 aa)
	Rtf1	RNA polymerase-associated protein RTF1 homolog. (717 aa)
	Ncoa6	Nuclear receptor coactivator 6 isoform X1. (2069 aa)
	Zfp335	Zinc finger protein 335. (1337 aa)
	Setd7	Histone-lysine N-methyltransferase SETD7. (366 aa)
	Setdb1	Histone-lysine N-methyltransferase SETDB1 isoform X1. (1305 aa)
	Tet2	Methylcytosine dioxygenase TET2/3. (1909 aa)
	Nfyc	Nuclear transcription factor Y subunit gamma. (335 aa)
	Rlf	Zinc finger protein Rlf. (1918 aa)
	2510039O18Rik	Uncharacterized protein KIAA2013 homolog isoform X1. (634 aa)
	Chd5	Chromodomain-helicase-DNA-binding protein 5 isoform X1. (1949 aa)
	Kmt2c	[histone H3]-lysine4 N-trimethyltransferase MLL3. (4903 aa)
	Paxip1	PAX-interacting protein 1 isoform X1. (1057 aa)
	Nsd2	Histone-lysine N-methyltransferase NSD2 isoform X1. (1367 aa)
	Prdm8	PR domain zinc finger protein 8. (688 aa)
	Setd1b	[histone H3]-lysine4 N-trimethyltransferase SETD1. (1984 aa)
	Kmt5a	[histone H4]-lysine20 N-methyltransferase SETD8. (364 aa)
	Gcc1	GRIP and coiled-coil domain-containing protein 1. (778 aa)
	Ezh2	[histone H3]-lysine27 N-trimethyltransferase EZH2. (732 aa)
	Prdm5	PR/SET domain 5. (599 aa)
	Smyd1	Histone-lysine N-methyltransferase SMYD1 isoform X1. (490 aa)
	Kdm3a	[histone H3]-dimethyl-L-lysine9 demethylase. (1323 aa)
	Tet3	Methylcytosine dioxygenase TET3 isoform X1. (1798 aa)
	Smyd5	SET and MYND domain-containing protein 5 isoform X1. (417 aa)
	Setmar	Histone-lysine N-methyltransferase SETMAR isoform X1. (309 aa)
	Setd5	SET domain-containing protein 5 isoform X1. (1460 aa)
	Kmt5c	[histone H4]-N-methyl-L-lysine20 N-methyltransferase. (470 aa)
	Dmrtc2	Doublesex- and mab-3-related transcription factor C2. (370 aa)
	Kmt2b	Histone-lysine N-methyltransferase 2B isoform X1. (2715 aa)
	Ctr9	RNA polymerase-associated protein CTR9 homolog. (1173 aa)
	Pagr1-2	PAXIP1-associated glutamate-rich protein 1. (253 aa)
	Pagr1	PAXIP1 associated glutamate rich protein 1. (253 aa)
	Setd1a	[histone H3]-lysine4 N-trimethyltransferase SETD1. (1725 aa)
	Ash2l	Set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1. (623 aa)
	Setd6	N-lysine methyltransferase SETD6 isoform X1. (473 aa)
	Kmt2a	Histone-lysine N-methyltransferase 2A isoform X1. (3970 aa)
	Wdr61	WD repeat-containing protein 61 isoform X1. (305 aa)
	Wdr82	WD repeat-containing protein 82. (313 aa)
	Setd2	[histone H3]-dimethyl-L-lysine36 N-methyltransferase. (2530 aa)
	Suv39h1	Histone-lysine N-methyltransferase SUV39H1 isoform X1. (413 aa)
	Ogt	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1. (1046 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arid4a	Arid4b	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0033715	AT-rich interactive domain-containing protein 4A.	AT-rich interactive domain-containing protein 4B.	0.557
Arid4a	Chd5	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0066093	AT-rich interactive domain-containing protein 4A.	Chromodomain-helicase-DNA-binding protein 5 isoform X1.	0.658
Arid4a	Cxxc1	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0047121	AT-rich interactive domain-containing protein 4A.	CXXC-type zinc finger protein 1 isoform X1.	0.502
Arid4a	Ezh1	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0029997	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase EZH1 isoform X1.	0.403
Arid4a	Ezh2	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0073595	AT-rich interactive domain-containing protein 4A.	[histone H3]-lysine27 N-trimethyltransferase EZH2.	0.403
Arid4a	Hdac2	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0022631	AT-rich interactive domain-containing protein 4A.	Histone deacetylase 1/2.	0.911
Arid4a	Nsd2	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0067589	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase NSD2 isoform X1.	0.413
Arid4a	Ogt	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0092357	AT-rich interactive domain-containing protein 4A.	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1.	0.593
Arid4a	Setbp1	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0047216	AT-rich interactive domain-containing protein 4A.	SET-binding protein.	0.616
Arid4a	Setd1a	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0082514	AT-rich interactive domain-containing protein 4A.	[histone H3]-lysine4 N-trimethyltransferase SETD1.	0.467
Arid4a	Setd1b	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0070673	AT-rich interactive domain-containing protein 4A.	[histone H3]-lysine4 N-trimethyltransferase SETD1.	0.467
Arid4a	Setd2	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0090277	AT-rich interactive domain-containing protein 4A.	[histone H3]-dimethyl-L-lysine36 N-methyltransferase.	0.556
Arid4a	Setd7	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0057600	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase SETD7.	0.403
Arid4a	Tet2	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0060598	AT-rich interactive domain-containing protein 4A.	Methylcytosine dioxygenase TET2/3.	0.480
Arid4a	Tet3	MGP_CAROLIEiJ_P0032470	MGP_CAROLIEiJ_P0074591	AT-rich interactive domain-containing protein 4A.	Methylcytosine dioxygenase TET3 isoform X1.	0.480
Arid4b	Arid4a	MGP_CAROLIEiJ_P0033715	MGP_CAROLIEiJ_P0032470	AT-rich interactive domain-containing protein 4B.	AT-rich interactive domain-containing protein 4A.	0.557
Arid4b	Chd5	MGP_CAROLIEiJ_P0033715	MGP_CAROLIEiJ_P0066093	AT-rich interactive domain-containing protein 4B.	Chromodomain-helicase-DNA-binding protein 5 isoform X1.	0.658
Arid4b	Cxxc1	MGP_CAROLIEiJ_P0033715	MGP_CAROLIEiJ_P0047121	AT-rich interactive domain-containing protein 4B.	CXXC-type zinc finger protein 1 isoform X1.	0.502
Arid4b	Ezh1	MGP_CAROLIEiJ_P0033715	MGP_CAROLIEiJ_P0029997	AT-rich interactive domain-containing protein 4B.	Histone-lysine N-methyltransferase EZH1 isoform X1.	0.403
Arid4b	Ezh2	MGP_CAROLIEiJ_P0033715	MGP_CAROLIEiJ_P0073595	AT-rich interactive domain-containing protein 4B.	[histone H3]-lysine27 N-trimethyltransferase EZH2.	0.403