(11 nodes) CD4 receptor binding network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cd22	B-cell receptor CD22 isoform X1. (867 aa)
	1700057G04Rik	Phospholipid scramblase 2. (232 aa)
	Plscr2	Phospholipid scramblase 2. (307 aa)
	Plscr1	Phospholipid scramblase 1. (327 aa)
	Spg21	Maspardin. (308 aa)
	Il16	Pro-interleukin-16. (1322 aa)
	Lck	Lymphocyte cell-specific protein tyrosine kinase. (520 aa)
	Cd74	HLA class II histocompatibility antigen gamma chain isoform X1. (331 aa)
	H2-Eb2	H-2 class II histocompatibility antigen, I-E beta chain-like isoform X1. (284 aa)
	H2-Eb1	H-2 class II histocompatibility antigen, E-D beta chain isoform X1. (264 aa)
	Fyn	Tyrosine-protein kinase Fyn isoform X1. (572 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd74	H2-Eb1	MGP_CAROLIEiJ_P0046833	MGP_CAROLIEiJ_P0044197	HLA class II histocompatibility antigen gamma chain isoform X1.	H-2 class II histocompatibility antigen, E-D beta chain isoform X1.	0.999
Cd74	H2-Eb2	MGP_CAROLIEiJ_P0046833	MGP_CAROLIEiJ_P0044198	HLA class II histocompatibility antigen gamma chain isoform X1.	H-2 class II histocompatibility antigen, I-E beta chain-like isoform X1.	0.971
Fyn	Lck	MGP_CAROLIEiJ_P0022660	MGP_CAROLIEiJ_P0064617	Tyrosine-protein kinase Fyn isoform X1.	Lymphocyte cell-specific protein tyrosine kinase.	0.985
H2-Eb1	Cd74	MGP_CAROLIEiJ_P0044197	MGP_CAROLIEiJ_P0046833	H-2 class II histocompatibility antigen, E-D beta chain isoform X1.	HLA class II histocompatibility antigen gamma chain isoform X1.	0.999
H2-Eb1	H2-Eb2	MGP_CAROLIEiJ_P0044197	MGP_CAROLIEiJ_P0044198	H-2 class II histocompatibility antigen, E-D beta chain isoform X1.	H-2 class II histocompatibility antigen, I-E beta chain-like isoform X1.	0.944
H2-Eb1	Lck	MGP_CAROLIEiJ_P0044197	MGP_CAROLIEiJ_P0064617	H-2 class II histocompatibility antigen, E-D beta chain isoform X1.	Lymphocyte cell-specific protein tyrosine kinase.	0.406
H2-Eb2	Cd74	MGP_CAROLIEiJ_P0044198	MGP_CAROLIEiJ_P0046833	H-2 class II histocompatibility antigen, I-E beta chain-like isoform X1.	HLA class II histocompatibility antigen gamma chain isoform X1.	0.971
H2-Eb2	H2-Eb1	MGP_CAROLIEiJ_P0044198	MGP_CAROLIEiJ_P0044197	H-2 class II histocompatibility antigen, I-E beta chain-like isoform X1.	H-2 class II histocompatibility antigen, E-D beta chain isoform X1.	0.944
Lck	Fyn	MGP_CAROLIEiJ_P0064617	MGP_CAROLIEiJ_P0022660	Lymphocyte cell-specific protein tyrosine kinase.	Tyrosine-protein kinase Fyn isoform X1.	0.985
Lck	H2-Eb1	MGP_CAROLIEiJ_P0064617	MGP_CAROLIEiJ_P0044197	Lymphocyte cell-specific protein tyrosine kinase.	H-2 class II histocompatibility antigen, E-D beta chain isoform X1.	0.406