(36 nodes) Regulation of long-term neuronal synaptic plasticity network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Egr1	Early growth response protein 1. (533 aa)
	Rab5a	Ras-related protein Rab-5A. (182 aa)
	Syngap1	Ras/Rap GTPase-activating protein SynGAP. (1340 aa)
	Grik1	Glutamate receptor ionotropic, kainate 1. (877 aa)
	App	Amyloid beta precursor protein. (695 aa)
	Grin2a	Glutamate receptor ionotropic, NMDA 2A isoform X1. (1464 aa)
	Shank3	SH3 and multiple ankyrin repeat domains protein 3. (1805 aa)
	Syngr1	Synaptogyrin-1 isoform X1. (234 aa)
	Camk2g	Calcium/calmodulin dependent protein kinase II gamma. (529 aa)
	Synpr	Synaptoporin isoform X1. (285 aa)
	Nf1	Neurofibromin. (2841 aa)
	Dlg4	Disks large homolog 4 isoform X1. (767 aa)
	Camk2b	Calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (666 aa)
	S100b	Protein S100-B. (92 aa)
	Grik2	Glutamate receptor ionotropic, kainate 2 isoform X1. (908 aa)
	Kcnj10	Potassium inwardly-rectifying channel subfamily J member 10. (379 aa)
	Fcgr2b	Fc receptor, IgG, low affinity IIb. (340 aa)
	Rims1	Regulating synaptic membrane exocytosis protein 1 isoform X1. (804 aa)
	Hras	GTPase HRas isoform X1. (189 aa)
	Rab8a	Ras-related protein Rab-8A. (207 aa)
	Drd2	D(2) dopamine receptor. (444 aa)
	Nptn	Neuroplastin isoform X1. (397 aa)
	Rab11a	Ras-related protein Rab-11A. (216 aa)
	Syp	Synaptophysin. (314 aa)
	Fmr1	FMRP translational regulator 1. (631 aa)
	Grm5	Metabotropic glutamate receptor 5 isoform X1. (1203 aa)
	Kras	GTPase KRas isoform X1. (189 aa)
	Grin2b	Glutamate receptor ionotropic, NMDA 2B. (1482 aa)
	Snca	Alpha-synuclein isoform X1. (140 aa)
	Kdr	Vascular endothelial growth factor receptor 2. (1345 aa)
	Kit	Mast/stem cell growth factor receptor Kit isoform X1. (979 aa)
	Ephb2	Ephrin type-B receptor 2 isoform X1. (987 aa)
	Bdnf	LOW QUALITY PROTEIN: brain-derived neurotrophic factor. (289 aa)
	Grin1	Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
	Neurl1a	E3 ubiquitin-protein ligase NEURL1 isoform X1. (574 aa)
	Synpo	Synaptopodin isoform X1. (1103 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
App	Bdnf	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0053564	Amyloid beta precursor protein.	LOW QUALITY PROTEIN: brain-derived neurotrophic factor.	0.724
App	Dlg4	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0027746	Amyloid beta precursor protein.	Disks large homolog 4 isoform X1.	0.687
App	Ephb2	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0065282	Amyloid beta precursor protein.	Ephrin type-B receptor 2 isoform X1.	0.590
App	Fcgr2b	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0021090	Amyloid beta precursor protein.	Fc receptor, IgG, low affinity IIb.	0.601
App	Fmr1	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0091575	Amyloid beta precursor protein.	FMRP translational regulator 1.	0.681
App	Grin1	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0050102	Amyloid beta precursor protein.	Glutamate receptor ionotropic, NMDA 1 isoform X1.	0.743
App	Grin2a	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0040314	Amyloid beta precursor protein.	Glutamate receptor ionotropic, NMDA 2A isoform X1.	0.650
App	Grin2b	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0076507	Amyloid beta precursor protein.	Glutamate receptor ionotropic, NMDA 2B.	0.707
App	Grm5	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0080591	Amyloid beta precursor protein.	Metabotropic glutamate receptor 5 isoform X1.	0.601
App	Hras	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0083141	Amyloid beta precursor protein.	GTPase HRas isoform X1.	0.569
App	Kras	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0076811	Amyloid beta precursor protein.	GTPase KRas isoform X1.	0.569
App	Nf1	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0028640	Amyloid beta precursor protein.	Neurofibromin.	0.613
App	S100b	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0023491	Amyloid beta precursor protein.	Protein S100-B.	0.621
App	Snca	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0074093	Amyloid beta precursor protein.	Alpha-synuclein isoform X1.	0.878
App	Syp	MGP_CAROLIEiJ_P0042114	MGP_CAROLIEiJ_P0090820	Amyloid beta precursor protein.	Synaptophysin.	0.726
Bdnf	App	MGP_CAROLIEiJ_P0053564	MGP_CAROLIEiJ_P0042114	LOW QUALITY PROTEIN: brain-derived neurotrophic factor.	Amyloid beta precursor protein.	0.724
Bdnf	Dlg4	MGP_CAROLIEiJ_P0053564	MGP_CAROLIEiJ_P0027746	LOW QUALITY PROTEIN: brain-derived neurotrophic factor.	Disks large homolog 4 isoform X1.	0.668
Bdnf	Drd2	MGP_CAROLIEiJ_P0053564	MGP_CAROLIEiJ_P0087746	LOW QUALITY PROTEIN: brain-derived neurotrophic factor.	D(2) dopamine receptor.	0.597
Bdnf	Egr1	MGP_CAROLIEiJ_P0053564	MGP_CAROLIEiJ_P0046304	LOW QUALITY PROTEIN: brain-derived neurotrophic factor.	Early growth response protein 1.	0.599
Bdnf	Fmr1	MGP_CAROLIEiJ_P0053564	MGP_CAROLIEiJ_P0091575	LOW QUALITY PROTEIN: brain-derived neurotrophic factor.	FMRP translational regulator 1.	0.558