(55 nodes) Autonomic nervous system development network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gdnf	Glial cell line-derived neurotrophic factor isoform X1. (240 aa)
	Fn1	Fibronectin 1. (2477 aa)
	Nrp2	Neuropilin-2 isoform X1. (931 aa)
	Tfap2b	Transcription factor AP-2-beta isoform X1. (459 aa)
	Phox2b	Paired mesoderm homeobox protein 2B. (314 aa)
	Sema3a	Semaphorin-3A. (772 aa)
	Hes3	Hairy and enhancer of split 3. (197 aa)
	Phactr4	Phosphatase and actin regulator 4. (681 aa)
	Vcam1	Vascular cell adhesion molecule 1. (739 aa)
	Ntrk1	High affinity nerve growth factor receptor isoform X1. (799 aa)
	Insm1	Insulinoma-associated protein 1. (521 aa)
	Gata3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (443 aa)
	Gfra3	GDNF family receptor alpha-3. (397 aa)
	Sox8	Transcription factor SOX7/8/10/18 (SOX group E/F). (464 aa)
	Hes1	Hairy and enhancer of split 1. (281 aa)
	Trp63	Tumor protein 63 isoform X1. (680 aa)
	Tbx1	T-box transcription factor TBX1 isoform X1. (488 aa)
	Sox10	Transcription factor SOX7/8/10/18 (SOX group E/F). (466 aa)
	Ednrb	Endothelin receptor type B. (442 aa)
	Fzd3	Frizzled 3. (666 aa)
	Tfap2a	Transcription factor AP-2-alpha isoform X1. (440 aa)
	Sox4	Transcription factor SOX4 (SOX group C). (440 aa)
	Kif26a	Kinesin-like protein KIF26A isoform X1. (1884 aa)
	Six1	Homeobox protein SIX1. (284 aa)
	Sox11	Transcription factor SOX11/12 (SOX group C). (395 aa)
	Erbb2	Receptor tyrosine-protein kinase erbB-2. (1258 aa)
	Hoxb1	Homeobox protein HoxA/B/D1. (297 aa)
	Hoxb2	Homeobox protein HoxA/B2. (354 aa)
	Nf1	Neurofibromin. (2841 aa)
	Ascl1	Achaete-scute complex protein. (231 aa)
	Adarb1	Double stranded RNA-specific editase B. (711 aa)
	Egr2	E3 SUMO-protein ligase EGR2 isoform X1. (470 aa)
	Hlx	H2.0-like homeobox protein. (476 aa)
	Prlh	Prolactin-releasing peptide. (86 aa)
	Ackr3	C-X-C chemokine receptor type 7 (atypical chemokine receptor 3). (362 aa)
	Gbx2	Homeobox protein GBX-2 isoform X1. (348 aa)
	Hoxa1	Homeobox protein Hox-A1 isoform X1. (336 aa)
	Tlx2	T-cell leukemia homeobox protein 2. (284 aa)
	MGP_CAROLIEiJ_P0075713	annotation not available (1024 aa)
	Ntf3	Neurotrophin-3 isoform X1. (271 aa)
	Nav2	Neuron navigator 2. (2433 aa)
	Phox2a	Paired mesoderm homeobox protein 2A. (280 aa)
	Hand2	Heart- and neural crest derivatives-expressed protein 2. (217 aa)
	Isx	Intestine-specific homeobox isoform X1. (242 aa)
	Ednra	Endothelin receptor type A. (427 aa)
	Nrp1	Neuropilin-1 isoform X1. (923 aa)
	Sema3f	Semaphorin-3F isoform X1. (785 aa)
	Ctnnb1	Catenin beta 1. (781 aa)
	Gm9	Uncharacterized protein LOC110287406. (157 aa)
	Rhox5	Homeobox protein Rhox5 isoform X1. (213 aa)
	Rhox10	Rhox homeobox family member 1-like. (201 aa)
	Rhox11	Rhox homeobox family member 1-like. (209 aa)
	Plxna3	Plexin-A3 isoform X1. (1872 aa)
	Arx	Homeobox protein aristaless-related. (565 aa)
	Plxna4	Plexin-A4 isoform X1. (1893 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arx	Tlx2	MGP_CAROLIEiJ_P0092095	MGP_CAROLIEiJ_P0074504	Homeobox protein aristaless-related.	T-cell leukemia homeobox protein 2.	0.405
Ascl1	Hes1	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0041175	Achaete-scute complex protein.	Hairy and enhancer of split 1.	0.614
Ascl1	Insm1	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0055042	Achaete-scute complex protein.	Insulinoma-associated protein 1.	0.574
Ascl1	Phox2a	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0081015	Achaete-scute complex protein.	Paired mesoderm homeobox protein 2A.	0.527
Ascl1	Phox2b	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0068439	Achaete-scute complex protein.	Paired mesoderm homeobox protein 2B.	0.569
Ascl1	Sox10	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0038919	Achaete-scute complex protein.	Transcription factor SOX7/8/10/18 (SOX group E/F).	0.556
Ascl1	Sox11	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0032024	Achaete-scute complex protein.	Transcription factor SOX11/12 (SOX group C).	0.501
Ascl1	Sox4	MGP_CAROLIEiJ_P0024379	MGP_CAROLIEiJ_P0033997	Achaete-scute complex protein.	Transcription factor SOX4 (SOX group C).	0.502
Ctnnb1	Erbb2	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0029653	Catenin beta 1.	Receptor tyrosine-protein kinase erbB-2.	0.980
Ctnnb1	Fn1	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0018183	Catenin beta 1.	Fibronectin 1.	0.552
Ctnnb1	Fzd3	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0037138	Catenin beta 1.	Frizzled 3.	0.707
Ctnnb1	Gata3	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0049509	Catenin beta 1.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.403
Ctnnb1	Hes1	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0041175	Catenin beta 1.	Hairy and enhancer of split 1.	0.412
Ctnnb1	MGP_CAROLIEiJ_P0075713	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0075713	Catenin beta 1.	annotation not available	0.458
Ctnnb1	Nf1	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0028640	Catenin beta 1.	Neurofibromin.	0.429
Ctnnb1	Sox10	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0038919	Catenin beta 1.	Transcription factor SOX7/8/10/18 (SOX group E/F).	0.653
Ctnnb1	Sox11	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0032024	Catenin beta 1.	Transcription factor SOX11/12 (SOX group C).	0.558
Ctnnb1	Sox4	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0033997	Catenin beta 1.	Transcription factor SOX4 (SOX group C).	0.787
Ctnnb1	Sox8	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0043282	Catenin beta 1.	Transcription factor SOX7/8/10/18 (SOX group E/F).	0.560
Ctnnb1	Vcam1	MGP_CAROLIEiJ_P0090603	MGP_CAROLIEiJ_P0060107	Catenin beta 1.	Vascular cell adhesion molecule 1.	0.461