(34 nodes) Regulation of axon regeneration network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rtn4r	Reticulon-4 receptor. (473 aa)
	Ptprs	Receptor-type tyrosine-protein phosphatase S isoform X1. (1907 aa)
	Cntf	Ciliary neurotrophic factor. (198 aa)
	Pten	Phosphatase and tensin homolog. (403 aa)
	Cers2	Ceramide synthase 2. (380 aa)
	Lrig2	Leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1. (1054 aa)
	Klf4	Krueppel-like factor 4. (483 aa)
	Ptprf	Receptor-type tyrosine-protein phosphatase F. (1898 aa)
	Ocm	Putative oncomodulin-2. (109 aa)
	Ptn	Pleiotrophin isoform X1. (168 aa)
	Braf	B-Raf proto-oncogene serine/threonine-protein kinase. (804 aa)
	Klk8	Kallikrein 8. (260 aa)
	Igf1r	Insulin-like growth factor 1 receptor. (1373 aa)
	Lrp1	Low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor). (4545 aa)
	Kremen1	Kremen protein 1. (473 aa)
	Ndel1	Nuclear distribution protein nudE-like 1 isoform X1. (345 aa)
	Rtn4rl1	Reticulon-4 receptor-like 1. (445 aa)
	Ntrk3	Neurotrophic tyrosine kinase, receptor type 3. (864 aa)
	Xylt1	Protein xylosyltransferase. (959 aa)
	Inpp5f	Phosphatidylinositide phosphatase SAC2 isoform X1. (1132 aa)
	Nrg1	Pro-neuregulin-1, membrane-bound isoform isoform X1. (700 aa)
	Neo1	Neogenin. (1492 aa)
	Map2k1	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1. (393 aa)
	Flna	Filamin-A isoform X1. (2647 aa)
	Scarf1	Scavenger receptor class F member 1 isoform X1. (815 aa)
	Omg	Oligodendrocyte myelin glycoprotein. (443 aa)
	Tnr	Tenascin-R isoform X1. (1358 aa)
	Epha4	Ephrin type-A receptor 4 isoform X1. (986 aa)
	Grn	Progranulin. (602 aa)
	Fkbp1b	Peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1. (108 aa)
	Adam17	Disintegrin and metalloproteinase domain-containing protein 17. (846 aa)
	D130043K22Rik	Dyslexia-associated protein KIAA0319 homolog isoform X1. (1081 aa)
	Stk24	Serine/threonine-protein kinase 24/25/MST4. (431 aa)
	Map2k2	Dual specificity mitogen-activated protein kinase kinase 2 isoform X1. (401 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adam17	Nrg1	MGP_CAROLIEiJ_P0031984	MGP_CAROLIEiJ_P0084135	Disintegrin and metalloproteinase domain-containing protein 17.	Pro-neuregulin-1, membrane-bound isoform isoform X1.	0.423
Braf	Map2k1	MGP_CAROLIEiJ_P0073389	MGP_CAROLIEiJ_P0088300	B-Raf proto-oncogene serine/threonine-protein kinase.	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1.	0.998
Braf	Map2k2	MGP_CAROLIEiJ_P0073389	MGP_CAROLIEiJ_P0024055	B-Raf proto-oncogene serine/threonine-protein kinase.	Dual specificity mitogen-activated protein kinase kinase 2 isoform X1.	0.988
Braf	Pten	MGP_CAROLIEiJ_P0073389	MGP_CAROLIEiJ_P0048585	B-Raf proto-oncogene serine/threonine-protein kinase.	Phosphatase and tensin homolog.	0.760
Cntf	Ntrk3	MGP_CAROLIEiJ_P0048290	MGP_CAROLIEiJ_P0080155	Ciliary neurotrophic factor.	Neurotrophic tyrosine kinase, receptor type 3.	0.615
Cntf	Ocm	MGP_CAROLIEiJ_P0048290	MGP_CAROLIEiJ_P0072062	Ciliary neurotrophic factor.	Putative oncomodulin-2.	0.519
Epha4	Ptn	MGP_CAROLIEiJ_P0018578	MGP_CAROLIEiJ_P0073254	Ephrin type-A receptor 4 isoform X1.	Pleiotrophin isoform X1.	0.431
Fkbp1b	Ocm	MGP_CAROLIEiJ_P0031850	MGP_CAROLIEiJ_P0072062	Peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1.	Putative oncomodulin-2.	0.438
Igf1r	Map2k1	MGP_CAROLIEiJ_P0080088	MGP_CAROLIEiJ_P0088300	Insulin-like growth factor 1 receptor.	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1.	0.544
Igf1r	Map2k2	MGP_CAROLIEiJ_P0080088	MGP_CAROLIEiJ_P0024055	Insulin-like growth factor 1 receptor.	Dual specificity mitogen-activated protein kinase kinase 2 isoform X1.	0.475
Igf1r	Pten	MGP_CAROLIEiJ_P0080088	MGP_CAROLIEiJ_P0048585	Insulin-like growth factor 1 receptor.	Phosphatase and tensin homolog.	0.694
Igf1r	Ptn	MGP_CAROLIEiJ_P0080088	MGP_CAROLIEiJ_P0073254	Insulin-like growth factor 1 receptor.	Pleiotrophin isoform X1.	0.431
Igf1r	Ptprf	MGP_CAROLIEiJ_P0080088	MGP_CAROLIEiJ_P0063996	Insulin-like growth factor 1 receptor.	Receptor-type tyrosine-protein phosphatase F.	0.441
Igf1r	Ptprs	MGP_CAROLIEiJ_P0080088	MGP_CAROLIEiJ_P0045338	Insulin-like growth factor 1 receptor.	Receptor-type tyrosine-protein phosphatase S isoform X1.	0.427
Inpp5f	Pten	MGP_CAROLIEiJ_P0082672	MGP_CAROLIEiJ_P0048585	Phosphatidylinositide phosphatase SAC2 isoform X1.	Phosphatase and tensin homolog.	0.904
Klf4	Pten	MGP_CAROLIEiJ_P0062428	MGP_CAROLIEiJ_P0048585	Krueppel-like factor 4.	Phosphatase and tensin homolog.	0.432
Kremen1	Lrp1	MGP_CAROLIEiJ_P0025521	MGP_CAROLIEiJ_P0025043	Kremen protein 1.	Low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor).	0.550
Lrp1	Kremen1	MGP_CAROLIEiJ_P0025043	MGP_CAROLIEiJ_P0025521	Low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor).	Kremen protein 1.	0.550
Lrp1	Scarf1	MGP_CAROLIEiJ_P0025043	MGP_CAROLIEiJ_P0028263	Low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor).	Scavenger receptor class F member 1 isoform X1.	0.417
Map2k1	Braf	MGP_CAROLIEiJ_P0088300	MGP_CAROLIEiJ_P0073389	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1.	B-Raf proto-oncogene serine/threonine-protein kinase.	0.998