(101 nodes) Presynaptic active zone network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Canx	Calnexin. (591 aa)
	Arhgap44	Rho GTPase-activating protein 44 isoform X1. (814 aa)
	C1qbp	Complement component 1 Q subcomponent-binding protein, mitochondrial. (280 aa)
	Zzef1	Zinc finger ZZ-type and EF-hand domain-containing protein 1. (2936 aa)
	P2rx1	P2X purinoceptor 1. (399 aa)
	Flot2	Flotillin 2. (428 aa)
	Phb	LOW QUALITY PROTEIN: prohibitin. (207 aa)
	Cntnap1	Contactin associated protein 1. (1381 aa)
	Ntrk2	BDNF/NT-3 growth factors receptor isoform X1. (821 aa)
	Kcnma1	Potassium calcium-activated channel subfamily M alpha 1. (1239 aa)
	Erc2	ELKS/RAB6-interacting/CAST family member 2. (1002 aa)
	Cacna1d	Voltage-dependent L-type calcium channel subunit alpha-1D isoform X1. (2166 aa)
	Nufip1	Nuclear fragile X mental retardation-interacting protein 1. (484 aa)
	Egflam	Pikachurin isoform X1. (1017 aa)
	Cdh10	Cadherin 10, type 2, T2-cadherin. (788 aa)
	Rims2	Regulating synaptic membrane exocytosis 2. (1572 aa)
	Adcy8	Adenylate cyclase type 8 isoform X1. (1251 aa)
	Scn8a	Sodium channel protein type 8 subunit alpha isoform X1. (1988 aa)
	Stx19	Syntaxin 11. (292 aa)
	App	Amyloid beta precursor protein. (695 aa)
	Cacna1h	Voltage-dependent T-type calcium channel subunit alpha-1H. (2359 aa)
	Grm4	Metabotropic glutamate receptor 4 isoform X1. (912 aa)
	Flot1	Flotillin-1. (429 aa)
	Nrxn1	Neurexin-1 isoform X1. (1514 aa)
	Cdh2	Cadherin 2, type 1, N-cadherin. (906 aa)
	Stx3	Syntaxin-3 isoform X1. (289 aa)
	Apba1	Amyloid beta A4 precursor protein-binding family A member 1. (844 aa)
	Adra2a	Adrenergic receptor alpha-2A. (465 aa)
	Ntng2	Netrin-G2 isoform X1. (589 aa)
	Stxbp1	Syntaxin-binding protein 1. (1089 aa)
	Gad1	Glutamate decarboxylase 1 isoform X1. (593 aa)
	MGP_CAROLIEiJ_P0052606	annotation not available (897 aa)
	Ctnnd1	Catenin (cadherin-associated protein), delta 1. (905 aa)
	Snap25	Synaptosomal-associated protein 25 isoform X1. (206 aa)
	Ppfia2	Liprin-alpha-2 isoform X1. (1257 aa)
	MGP_CAROLIEiJ_P0024640	annotation not available (444 aa)
	Atp2b1	Plasma membrane calcium-transporting ATPase 1. (1220 aa)
	Adora2a	Adenosine receptor A2a. (410 aa)
	Stx11	Syntaxin 11. (287 aa)
	Ppfia4	Liprin-alpha-4 isoform X1. (1181 aa)
	Adora1	Adenosine receptor A1. (326 aa)
	Atp2b4	Plasma membrane calcium-transporting ATPase 4 isoform X1. (1205 aa)
	Ctnna2	Catenin alpha-2 isoform X1. (966 aa)
	Rims1	Regulating synaptic membrane exocytosis protein 1 isoform X1. (804 aa)
	Ncoa2	Nuclear receptor coactivator 2 isoform X1. (1464 aa)
	Phb2	Prohibitin 2. (299 aa)
	Dgki	Diacylglycerol kinase iota isoform X1. (1071 aa)
	Grm8	Metabotropic glutamate receptor 8 isoform X1. (908 aa)
	Gper1	G-protein coupled estrogen receptor 1. (375 aa)
	Stx1a	Syntaxin 1A. (237 aa)
	Stx2	Syntaxin-2 isoform X1. (289 aa)
	Rimbp2	RIMS-binding protein 2 isoform X1. (1079 aa)
	P2rx2	P2X purinoceptor 2 isoform X1. (485 aa)
	Ctbp1	C-terminal-binding protein 1 isoform X1. (441 aa)
	Slc32a1	Solute carrier family 32 (vesicular inhibitory amino acid transporter). (525 aa)
	P2ry1	P2Y purinoceptor 1. (373 aa)
	Gucy1b1	Guanylate cyclase soluble subunit beta-1. (620 aa)
	Syt11	Synaptotagmin-11. (430 aa)
	Sv2a	MFS transporter, VNT family, synaptic vesicle glycoprotein 2. (742 aa)
	Ntng1	Netrin-G1 isoform X1. (539 aa)
	Pnisr	Arginine/serine-rich protein PNISR isoform X1. (814 aa)
	Unc13b	Protein unc-13 homolog B isoform X1. (1609 aa)
	Rims3	Regulating synaptic membrane exocytosis protein 3. (307 aa)
	Tprgl	Tumor protein p63-regulated gene 1-like protein. (266 aa)
	Cacna2d1	Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1103 aa)
	Grm3	Metabotropic glutamate receptor 3. (879 aa)
	Grm7	Metabotropic glutamate receptor 7 isoform X1. (922 aa)
	Atp2b2	Plasma membrane calcium-transporting ATPase 2 isoform X1. (1243 aa)
	Erc1	ELKS/RAB6-interacting/CAST family member 1. (1049 aa)
	Iqsec2	IQ motif and SEC7 domain-containing protein 2 isoform X1. (1488 aa)
	LOC110286339	Syntaxin 1B/2/3. (296 aa)
	P2ry4	P2Y purinoceptor 4. (361 aa)
	Syn1	Synapsin-1 isoform X1. (706 aa)
	Syp	Synaptophysin. (314 aa)
	Ctnnb1	Catenin beta 1. (781 aa)
	Bsn	Protein bassoon. (3937 aa)
	Snap91	Clathrin coat assembly protein AP180. (830 aa)
	Unc13c	Protein unc-13 homolog C. (2210 aa)
	Nptn	Neuroplastin isoform X1. (397 aa)
	Cplx3	Complexin-3/4. (158 aa)
	Vps11	Vacuolar protein sorting-associated protein 11 homolog. (941 aa)
	Nectin1	Poliovirus receptor-related protein 1. (516 aa)
	Cacna1a	Voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X1. (2367 aa)
	Nr3c2	Mineralocorticoid receptor. (984 aa)
	Unc13a	Protein unc-13 homolog A. (1733 aa)
	Rab3a	Ras-related protein Rab-3A isoform X1. (220 aa)
	Lpar2	Lysophosphatidic acid receptor 2. (348 aa)
	Gpm6a	Neuronal membrane glycoprotein M6-a isoform X1. (278 aa)
	Nrg1	Pro-neuregulin-1, membrane-bound isoform isoform X1. (700 aa)
	Ppfia1	PTPRF interacting protein alpha 1. (1266 aa)
	Shank2	SH3 and multiple ankyrin repeat domains protein 2. (1841 aa)
	Ctbp2	C-terminal-binding protein 2 isoform X1. (988 aa)
	Stx4a	Syntaxin 4. (298 aa)
	Stx1b	Syntaxin-1B isoform X1. (288 aa)
	Ppfibp2	Liprin-beta-2. (904 aa)
	P2ry2	P2Y purinoceptor 2. (373 aa)
	Ppfia3	Liprin-alpha-3. (1194 aa)
	Slc17a7	Vesicular glutamate transporter 1 isoform X1. (560 aa)
	Lrfn3	Leucine-rich repeat and fibronectin type-III domain-containing protein 3. (626 aa)
	Brsk1	Serine/threonine-protein kinase BRSK1. (778 aa)
	Ppfibp1	Liprin-beta-1 isoform X1. (980 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adcy8	Grm3	MGP_CAROLIEiJ_P0038340	MGP_CAROLIEiJ_P0066702	Adenylate cyclase type 8 isoform X1.	Metabotropic glutamate receptor 3.	0.404
Adora1	Adora2a	MGP_CAROLIEiJ_P0019940	MGP_CAROLIEiJ_P0023404	Adenosine receptor A1.	Adenosine receptor A2a.	0.851
Adora1	P2ry1	MGP_CAROLIEiJ_P0019940	MGP_CAROLIEiJ_P0057830	Adenosine receptor A1.	P2Y purinoceptor 1.	0.603
Adora2a	Adora1	MGP_CAROLIEiJ_P0023404	MGP_CAROLIEiJ_P0019940	Adenosine receptor A2a.	Adenosine receptor A1.	0.851
Adora2a	Grm8	MGP_CAROLIEiJ_P0023404	MGP_CAROLIEiJ_P0072845	Adenosine receptor A2a.	Metabotropic glutamate receptor 8 isoform X1.	0.575
Adora2a	Ntrk2	MGP_CAROLIEiJ_P0023404	MGP_CAROLIEiJ_P0034616	Adenosine receptor A2a.	BDNF/NT-3 growth factors receptor isoform X1.	0.793
Adora2a	P2ry1	MGP_CAROLIEiJ_P0023404	MGP_CAROLIEiJ_P0057830	Adenosine receptor A2a.	P2Y purinoceptor 1.	0.548
Adora2a	P2ry2	MGP_CAROLIEiJ_P0023404	MGP_CAROLIEiJ_P0080951	Adenosine receptor A2a.	P2Y purinoceptor 2.	0.574
Adra2a	Cacna1a	MGP_CAROLIEiJ_P0049147	MGP_CAROLIEiJ_P0085239	Adrenergic receptor alpha-2A.	Voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform X1.	0.746
Apba1	App	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0042114	Amyloid beta A4 precursor protein-binding family A member 1.	Amyloid beta precursor protein.	0.900
Apba1	LOC110286339	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0092518	Amyloid beta A4 precursor protein-binding family A member 1.	Syntaxin 1B/2/3.	0.449
Apba1	Ppfia1	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0083540	Amyloid beta A4 precursor protein-binding family A member 1.	PTPRF interacting protein alpha 1.	0.447
Apba1	Ppfia2	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0024694	Amyloid beta A4 precursor protein-binding family A member 1.	Liprin-alpha-2 isoform X1.	0.493
Apba1	Ppfia3	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0079484	Amyloid beta A4 precursor protein-binding family A member 1.	Liprin-alpha-3.	0.489
Apba1	Ppfia4	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0019944	Amyloid beta A4 precursor protein-binding family A member 1.	Liprin-alpha-4 isoform X1.	0.425
Apba1	Rims1	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0016900	Amyloid beta A4 precursor protein-binding family A member 1.	Regulating synaptic membrane exocytosis protein 1 isoform X1.	0.469
Apba1	Rims2	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0038128	Amyloid beta A4 precursor protein-binding family A member 1.	Regulating synaptic membrane exocytosis 2.	0.734
Apba1	Rims3	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0064187	Amyloid beta A4 precursor protein-binding family A member 1.	Regulating synaptic membrane exocytosis protein 3.	0.454
Apba1	Snap25	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0054880	Amyloid beta A4 precursor protein-binding family A member 1.	Synaptosomal-associated protein 25 isoform X1.	0.542
Apba1	Stx11	MGP_CAROLIEiJ_P0048408	MGP_CAROLIEiJ_P0022285	Amyloid beta A4 precursor protein-binding family A member 1.	Syntaxin 11.	0.458