(44 nodes) Brain morphogenesis network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Sox2	Transcription factor SOX2 (SOX group B). (319 aa)
	Gba	Glucosylceramidase. (515 aa)
	Gsx2	Homeobox protein GSH. (305 aa)
	Gak	Cyclin-G-associated kinase isoform X1. (1305 aa)
	Smo	Smoothened homolog. (793 aa)
	Ctnna2	Catenin alpha-2 isoform X1. (966 aa)
	Emx1	Homeobox protein EMX1 isoform X1. (257 aa)
	Fancd2	Fanconi anemia group D2 protein. (1450 aa)
	Bbs4	Bardet-Biedl syndrome 4 protein. (520 aa)
	Bbs2	Bardet-Biedl syndrome 2 protein. (721 aa)
	Uchl5	Ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1. (329 aa)
	Akt3	RAC-gamma serine/threonine-protein kinase. (479 aa)
	Psen2	Presenilin 2. (448 aa)
	Foxo3	Forkhead box protein O3. (672 aa)
	Pcnt	Pericentrin isoform X1. (2913 aa)
	Otx1	Homeobox protein OTX1 isoform X1. (356 aa)
	Fbxw11	F-box/WD repeat-containing protein 11 isoform X1. (563 aa)
	Prop1	Homeobox protein prophet of Pit-1. (223 aa)
	Pafah1b1	Platelet-activating factor acetylhydrolase IB subunit alpha. (410 aa)
	Slc6a4	Solute carrier family 6 (neurotransmitter transporter, serotonin) member 4. (630 aa)
	Nf1	Neurofibromin. (2841 aa)
	Gdf7	Growth/differentiation factor 7 isoform X1. (452 aa)
	Psen1	Presenilin 1. (467 aa)
	Fancc	Fanconi anemia, complementation group C. (591 aa)
	Hesx1	Homeobox protein expressed in ES cells 1. (185 aa)
	Wnt5a	Wingless-type MMTV integration site family, member 5. (380 aa)
	Otx2	Homeobox protein OTX2 isoform X1. (297 aa)
	Ift88	Intraflagellar transport protein 88 homolog. (825 aa)
	Spef2	Sperm flagellar protein 2 isoform X1. (1724 aa)
	Shank3	SH3 and multiple ankyrin repeat domains protein 3. (1805 aa)
	Afdn	Afadin isoform X1. (1904 aa)
	Sos1	Son of sevenless homolog 1. (1319 aa)
	Cdh2	Cadherin 2, type 1, N-cadherin. (906 aa)
	Ctnna1	Catenin alpha-1 isoform X1. (906 aa)
	Bbs1	Bardet-Biedl syndrome 1 protein. (593 aa)
	Vps51	Vacuolar protein sorting-associated protein 51 homolog. (782 aa)
	Pten	Phosphatase and tensin homolog. (403 aa)
	Hhex	Hematopoietically-expressed homeobox protein HHEX. (272 aa)
	Pax2	Paired box 2. (416 aa)
	Fgf8	Fibroblast growth factor 8 isoform X1. (268 aa)
	Slc4a10	Solute carrier family 4 (sodium bicarbonate transporter), member 10. (997 aa)
	Duox2	Dual oxidase 2. (1394 aa)
	Mkks	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
	Zfp335	Zinc finger protein 335. (1337 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Afdn	Cdh2	MGP_CAROLIEiJ_P0042772	MGP_CAROLIEiJ_P0046112	Afadin isoform X1.	Cadherin 2, type 1, N-cadherin.	0.620
Afdn	Ctnna1	MGP_CAROLIEiJ_P0042772	MGP_CAROLIEiJ_P0046312	Afadin isoform X1.	Catenin alpha-1 isoform X1.	0.932
Afdn	Ctnna2	MGP_CAROLIEiJ_P0042772	MGP_CAROLIEiJ_P0074398	Afadin isoform X1.	Catenin alpha-2 isoform X1.	0.953
Akt3	Foxo3	MGP_CAROLIEiJ_P0021490	MGP_CAROLIEiJ_P0022762	RAC-gamma serine/threonine-protein kinase.	Forkhead box protein O3.	0.974
Akt3	Nf1	MGP_CAROLIEiJ_P0021490	MGP_CAROLIEiJ_P0028640	RAC-gamma serine/threonine-protein kinase.	Neurofibromin.	0.459
Akt3	Pten	MGP_CAROLIEiJ_P0021490	MGP_CAROLIEiJ_P0048585	RAC-gamma serine/threonine-protein kinase.	Phosphatase and tensin homolog.	0.795
Bbs1	Bbs2	MGP_CAROLIEiJ_P0047548	MGP_CAROLIEiJ_P0085571	Bardet-Biedl syndrome 1 protein.	Bardet-Biedl syndrome 2 protein.	0.998
Bbs1	Bbs4	MGP_CAROLIEiJ_P0047548	MGP_CAROLIEiJ_P0088140	Bardet-Biedl syndrome 1 protein.	Bardet-Biedl syndrome 4 protein.	0.999
Bbs1	Ift88	MGP_CAROLIEiJ_P0047548	MGP_CAROLIEiJ_P0036952	Bardet-Biedl syndrome 1 protein.	Intraflagellar transport protein 88 homolog.	0.700
Bbs1	Mkks	MGP_CAROLIEiJ_P0047548	MGP_CAROLIEiJ_P0054884	Bardet-Biedl syndrome 1 protein.	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.	0.427
Bbs1	Smo	MGP_CAROLIEiJ_P0047548	MGP_CAROLIEiJ_P0072976	Bardet-Biedl syndrome 1 protein.	Smoothened homolog.	0.752
Bbs2	Bbs1	MGP_CAROLIEiJ_P0085571	MGP_CAROLIEiJ_P0047548	Bardet-Biedl syndrome 2 protein.	Bardet-Biedl syndrome 1 protein.	0.998
Bbs2	Bbs4	MGP_CAROLIEiJ_P0085571	MGP_CAROLIEiJ_P0088140	Bardet-Biedl syndrome 2 protein.	Bardet-Biedl syndrome 4 protein.	0.998
Bbs2	Ift88	MGP_CAROLIEiJ_P0085571	MGP_CAROLIEiJ_P0036952	Bardet-Biedl syndrome 2 protein.	Intraflagellar transport protein 88 homolog.	0.668
Bbs2	Mkks	MGP_CAROLIEiJ_P0085571	MGP_CAROLIEiJ_P0054884	Bardet-Biedl syndrome 2 protein.	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.	0.496
Bbs2	Smo	MGP_CAROLIEiJ_P0085571	MGP_CAROLIEiJ_P0072976	Bardet-Biedl syndrome 2 protein.	Smoothened homolog.	0.621
Bbs4	Bbs1	MGP_CAROLIEiJ_P0088140	MGP_CAROLIEiJ_P0047548	Bardet-Biedl syndrome 4 protein.	Bardet-Biedl syndrome 1 protein.	0.999
Bbs4	Bbs2	MGP_CAROLIEiJ_P0088140	MGP_CAROLIEiJ_P0085571	Bardet-Biedl syndrome 4 protein.	Bardet-Biedl syndrome 2 protein.	0.998
Bbs4	Mkks	MGP_CAROLIEiJ_P0088140	MGP_CAROLIEiJ_P0054884	Bardet-Biedl syndrome 4 protein.	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.	0.431
Bbs4	Pcnt	MGP_CAROLIEiJ_P0088140	MGP_CAROLIEiJ_P0023500	Bardet-Biedl syndrome 4 protein.	Pericentrin isoform X1.	0.488