(97 nodes) Roof of mouth development network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tbc1d32	Protein broad-minded. (1299 aa)
	Sgpl1	Sphinganine-1-phosphate aldolase. (199 aa)
	Arid5b	AT-rich interactive domain-containing protein 5B isoform X1. (1189 aa)
	Alx1	Cartilage homeoprotein 1. (326 aa)
	Gdf11	Growth differentiation factor 11. (406 aa)
	Wdpcp	WD repeat-containing and planar cell polarity effector protein fritz homolog. (723 aa)
	Nprl3	Nitrogen permease regulator 3-like protein isoform X1. (569 aa)
	Wnt3a	Wingless-type MMTV integration site family, member 3. (352 aa)
	Tmem107	Transmembrane protein 107 isoform X1. (143 aa)
	Tbx2	T-box transcription factor TBX2. (711 aa)
	Wfikkn2	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (571 aa)
	Fzd2	Frizzled 2. (570 aa)
	Pkdcc	Extracellular tyrosine-protein kinase PKDCC&#160. (492 aa)
	Wnt8a	Wingless-type MMTV integration site family, member 8. (354 aa)
	Smad4	Mothers against decapentaplegic homolog 4. (551 aa)
	Smad2	Mothers against decapentaplegic homolog 2 isoform X1. (467 aa)
	Tshz1	Teashirt homolog 1. (1086 aa)
	Men1	Menin isoform X1. (617 aa)
	Vax1	Homeobox protein ventral anterior. (338 aa)
	Itgb6	Integrin beta 6. (787 aa)
	Alx4	Homeobox protein aristaless-like 4. (399 aa)
	Snai1	Zinc finger protein SNAI1. (264 aa)
	Bbs7	Bardet-Biedl syndrome 7 protein. (660 aa)
	Intu	Protein inturned. (942 aa)
	Tiparp	TCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
	Iqschfp	Schwannomin-interacting protein 1 isoform X1. (484 aa)
	Lef1	Lymphoid enhancer-binding factor 1 isoform X1. (397 aa)
	Chd7	Chromodomain-helicase-DNA-binding protein 7. (2986 aa)
	Asph	Aspartyl/asparaginyl beta-hydroxylase isoform X1. (741 aa)
	Foxe1	Forkhead box protein E1. (372 aa)
	Anp32b	Acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1. (272 aa)
	Tgfbr1	TGF-beta receptor type-1. (503 aa)
	Bnc2	Basonuclin 2. (1127 aa)
	Ephb2	Ephrin type-B receptor 2 isoform X1. (987 aa)
	Dhrs3	Short-chain dehydrogenase/reductase 3 isoform X1. (302 aa)
	Prdm16	PR domain zinc finger protein 16. (1276 aa)
	Ski	Ski oncogene. (727 aa)
	Fzd1	Frizzled 1/7. (642 aa)
	Insig1	Insulin-induced gene 1 protein. (259 aa)
	Shh	Sonic hedgehog protein isoform X1. (438 aa)
	MGP_CAROLIEiJ_P0067375	Intraflagellar transport protein 172 homolog. (207 aa)
	Msx1	Homeobox protein MSX-1. (303 aa)
	Pds5a	Sister chromatid cohesion protein PDS5 homolog A. (1285 aa)
	Pdgfra	Platelet-derived growth factor receptor alpha isoform X1. (1089 aa)
	Fras1	Extracellular matrix protein FRAS1. (4010 aa)
	Tgfbr3	Transforming growth factor beta receptor type 3. (850 aa)
	Tbx3	T-box transcription factor TBX3 isoform X1. (741 aa)
	Dlx6	Homeobox protein DLX1/4/6. (298 aa)
	Dlx5	Homeobox protein DLX-5 isoform X1. (289 aa)
	Loxl3	Lysyl oxidase homolog 3 isoform X1. (754 aa)
	Wnt7a	Wingless-type MMTV integration site family, member 7. (349 aa)
	Lrp6	Low-density lipoprotein receptor-related protein 6 isoform X1. (1613 aa)
	Fuz	Protein fuzzy homolog isoform X1. (415 aa)
	Gabrb3	Gamma-aminobutyric acid (GABA) A receptor, subunit beta 3. (507 aa)
	Lrrc32	Leucine-rich repeat-containing protein 32. (663 aa)
	Wnt11	Wingless-type MMTV integration site family, member 11. (354 aa)
	Hand2	Heart- and neural crest derivatives-expressed protein 2. (217 aa)
	Tgfbr2	TGF-beta receptor type-2 isoform X1. (592 aa)
	Acvr2b	Activin receptor type-2B. (536 aa)
	Bcor	BCL-6 corepressor isoform X1. (1759 aa)
	Wnt5a	Wingless-type MMTV integration site family, member 5. (380 aa)
	Mef2c	Myocyte-specific enhancer factor 2C isoform X1. (483 aa)
	Cdk20	Cyclin-dependent kinase 20. (346 aa)
	Pak1ip1	P21-activated protein kinase-interacting protein 1. (382 aa)
	Tfap2a	Transcription factor AP-2-alpha isoform X1. (440 aa)
	Foxf2	Forkhead box protein F2. (446 aa)
	Inhba	Inhibin beta A chain. (424 aa)
	Gli3	Transcriptional activator GLI3. (1583 aa)
	Itgb8	Integrin beta-8 isoform X1. (767 aa)
	Jag2	Protein jagged-2. (1247 aa)
	Tgfb3	Transforming growth factor beta-3. (412 aa)
	Meox2	Homeobox protein MOX-2. (303 aa)
	Twist1	Twist-related protein 1. (206 aa)
	Sox11	Transcription factor SOX11/12 (SOX group C). (395 aa)
	Osr1	Protein odd-skipped-related 1. (266 aa)
	Wnt9b	Wingless-type MMTV integration site family, member 9. (359 aa)
	Bmpr1a	Bone morphogenetic protein receptor type-1A. (532 aa)
	Ift88	Intraflagellar transport protein 88 homolog. (825 aa)
	Osr2	Protein odd-skipped-related 2 isoform X1. (276 aa)
	Col2a1	Collagen alpha-1(II) chain isoform X1. (1487 aa)
	Snai2	Zinc finger protein SNAI2. (269 aa)
	Tbx1	T-box transcription factor TBX1 isoform X1. (488 aa)
	Ephb3	Ephrin type-B receptor 3 isoform X1. (993 aa)
	Dlg1	Disks large homolog 1 isoform X1. (927 aa)
	Mmp25	Matrix metalloproteinase-25 (membrane-inserted). (614 aa)
	Wfikkn1	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1. (552 aa)
	Col11a2	Collagen type V/XI/XXIV/XXVII, alpha. (1689 aa)
	Sos1	Son of sevenless homolog 1. (1319 aa)
	Msc	Musculin (activated B-cell factor-1). (203 aa)
	Satb2	DNA-binding protein SATB2 isoform X1. (733 aa)
	Sumo1	Small ubiquitin-related modifier 1 isoform X1. (101 aa)
	Insig2	Insulin-induced gene 2 protein isoform X1. (225 aa)
	Prrx1	Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
	Tgfb2	Transforming growth factor beta-2 isoform X1. (442 aa)
	Irf6	Interferon regulatory factor 6. (467 aa)
	Tcf21	Transcription factor 21. (179 aa)
	MGP_CAROLIEiJ_P0022853	annotation not available (118 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acvr2b	Bmpr1a	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0036228	Activin receptor type-2B.	Bone morphogenetic protein receptor type-1A.	0.985
Acvr2b	Gdf11	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0025203	Activin receptor type-2B.	Growth differentiation factor 11.	0.997
Acvr2b	Inhba	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0033731	Activin receptor type-2B.	Inhibin beta A chain.	0.995
Acvr2b	Smad2	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0047151	Activin receptor type-2B.	Mothers against decapentaplegic homolog 2 isoform X1.	0.978
Acvr2b	Smad4	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0047101	Activin receptor type-2B.	Mothers against decapentaplegic homolog 4.	0.803
Acvr2b	Tgfb2	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0021818	Activin receptor type-2B.	Transforming growth factor beta-2 isoform X1.	0.433
Acvr2b	Tgfb3	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0032929	Activin receptor type-2B.	Transforming growth factor beta-3.	0.466
Acvr2b	Tgfbr1	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0062295	Activin receptor type-2B.	TGF-beta receptor type-1.	0.990
Acvr2b	Tgfbr2	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0090480	Activin receptor type-2B.	TGF-beta receptor type-2 isoform X1.	0.440
Acvr2b	Tgfbr3	MGP_CAROLIEiJ_P0090560	MGP_CAROLIEiJ_P0069514	Activin receptor type-2B.	Transforming growth factor beta receptor type 3.	0.707
Alx4	Gli3	MGP_CAROLIEiJ_P0053241	MGP_CAROLIEiJ_P0033730	Homeobox protein aristaless-like 4.	Transcriptional activator GLI3.	0.541
Alx4	Lef1	MGP_CAROLIEiJ_P0053241	MGP_CAROLIEiJ_P0060538	Homeobox protein aristaless-like 4.	Lymphoid enhancer-binding factor 1 isoform X1.	0.461
Alx4	Shh	MGP_CAROLIEiJ_P0053241	MGP_CAROLIEiJ_P0067069	Homeobox protein aristaless-like 4.	Sonic hedgehog protein isoform X1.	0.408
Bbs7	Ift88	MGP_CAROLIEiJ_P0057377	MGP_CAROLIEiJ_P0036952	Bardet-Biedl syndrome 7 protein.	Intraflagellar transport protein 88 homolog.	0.693
Bbs7	MGP_CAROLIEiJ_P0067375	MGP_CAROLIEiJ_P0057377	MGP_CAROLIEiJ_P0067375	Bardet-Biedl syndrome 7 protein.	Intraflagellar transport protein 172 homolog.	0.483
Bbs7	Wdpcp	MGP_CAROLIEiJ_P0057377	MGP_CAROLIEiJ_P0025829	Bardet-Biedl syndrome 7 protein.	WD repeat-containing and planar cell polarity effector protein fritz homolog.	0.534
Bmpr1a	Acvr2b	MGP_CAROLIEiJ_P0036228	MGP_CAROLIEiJ_P0090560	Bone morphogenetic protein receptor type-1A.	Activin receptor type-2B.	0.985
Bmpr1a	Gdf11	MGP_CAROLIEiJ_P0036228	MGP_CAROLIEiJ_P0025203	Bone morphogenetic protein receptor type-1A.	Growth differentiation factor 11.	0.502
Bmpr1a	Inhba	MGP_CAROLIEiJ_P0036228	MGP_CAROLIEiJ_P0033731	Bone morphogenetic protein receptor type-1A.	Inhibin beta A chain.	0.549
Bmpr1a	Meox2	MGP_CAROLIEiJ_P0036228	MGP_CAROLIEiJ_P0032158	Bone morphogenetic protein receptor type-1A.	Homeobox protein MOX-2.	0.402