(58 nodes) Lung morphogenesis network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rdh10	Retinol dehydrogenase 10. (341 aa)
	Cfc1	Cryptic protein. (201 aa)
	Vangl2	Vang-like protein 2 isoform X1. (521 aa)
	Tcf21	Transcription factor 21. (179 aa)
	Nodal	Nodal homolog. (354 aa)
	Map2k2	Dual specificity mitogen-activated protein kinase kinase 2 isoform X1. (401 aa)
	Igf1	Insulin-like growth factor I isoform X1. (165 aa)
	Tmtc3	Transmembrane and TPR repeat-containing protein 3. (920 aa)
	Lif	Leukemia inhibitory factor isoform X1. (203 aa)
	Tbx2	T-box transcription factor TBX2. (711 aa)
	Nog	Noggin. (232 aa)
	Sox9	Transcription factor SOX9 (SOX group E). (507 aa)
	Sox11	Transcription factor SOX11/12 (SOX group C). (395 aa)
	Nkx2-1	Homeobox protein Nkx-2.1 isoform X1. (372 aa)
	Foxa1	Forkhead box protein A1, hepatocyte nuclear factor 3-alpha. (468 aa)
	Ap3b1	AP-3 complex subunit beta-1. (1098 aa)
	Fgf10	Fibroblast growth factor 10. (209 aa)
	Dlg5	Disks large homolog 5 isoform X1. (1921 aa)
	Bmp4	Bone morphogenetic protein 4. (408 aa)
	Gata4	Transcription factor GATA-4. (442 aa)
	Spry2	Protein sprouty homolog 2. (315 aa)
	Grhl2	Transcription factor CP2 and related proteins. (625 aa)
	Ext1	Glucuronyl/N-acetylglucosaminyl transferase EXT1. (746 aa)
	Wnt7b	Wingless-type MMTV integration site family, member 7. (353 aa)
	Celsr1	Cadherin EGF LAG seven-pass G-type receptor 1. (3034 aa)
	Mapk1	Mitogen-activated protein kinase 1/3. (358 aa)
	LOC110311751	Disks large homolog 5-like isoform X1. (243 aa)
	Mapk8ip3	C-Jun-amino-terminal kinase-interacting protein 3 isoform X1. (1345 aa)
	Srf	Serum response factor. (504 aa)
	Hhex	Hematopoietically-expressed homeobox protein HHEX. (272 aa)
	Hps1	Hermansky-Pudlak syndrome 1 protein. (715 aa)
	Fgf8	Fibroblast growth factor 8 isoform X1. (268 aa)
	Foxa2	Forkhead box protein A2, hepatocyte nuclear factor 3-beta. (465 aa)
	Id1	DNA-binding protein inhibitor ID-1. (164 aa)
	Ctsz	Cathepsin X. (306 aa)
	Sox2	Transcription factor SOX2 (SOX group B). (319 aa)
	Spry1	Protein sprouty homolog 1. (313 aa)
	Pitx2	Paired-like homeodomain transcription factor 2. (324 aa)
	Sec24b	Protein transport protein Sec24B. (1241 aa)
	Esrp1	Epithelial splicing regulatory protein 1 isoform X1. (681 aa)
	Tnc	Tenascin isoform X1. (2110 aa)
	Stk40	Serine/threonine-protein kinase 40 isoform X1. (449 aa)
	Shh	Sonic hedgehog protein isoform X1. (438 aa)
	Foxp2	Forkhead box protein P2 isoform X1. (739 aa)
	Wnt2	Wingless-type MMTV integration site family, member 2. (360 aa)
	Hoxa5	Homeobox protein HoxA/B/C5. (270 aa)
	Kras	GTPase KRas isoform X1. (189 aa)
	Rpl13a	Large subunit ribosomal protein L13Ae. (203 aa)
	Mapk3	Mitogen-activated protein kinase 1/3. (380 aa)
	Fgfr2	Fibroblast growth factor receptor 2 isoform X1. (838 aa)
	Hhip	Hedgehog interacting protein. (700 aa)
	Esrp2	Epithelial splicing regulatory protein 2 isoform X1. (717 aa)
	Foxf1	Forkhead box protein F1. (378 aa)
	Yap1	Transcriptional coactivator YAP1 isoform X1. (488 aa)
	Map2k1	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1. (393 aa)
	Dag1	Dystroglycan 1. (893 aa)
	Tgfbr2	TGF-beta receptor type-2 isoform X1. (592 aa)
	Ctnnb1	Catenin beta 1. (781 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ap3b1	Hps1	MGP_CAROLIEiJ_P0035147	MGP_CAROLIEiJ_P0048850	AP-3 complex subunit beta-1.	Hermansky-Pudlak syndrome 1 protein.	0.586
Bmp4	Ctnnb1	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0090603	Bone morphogenetic protein 4.	Catenin beta 1.	0.613
Bmp4	Fgf10	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0035544	Bone morphogenetic protein 4.	Fibroblast growth factor 10.	0.715
Bmp4	Fgf8	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0048966	Bone morphogenetic protein 4.	Fibroblast growth factor 8 isoform X1.	0.645
Bmp4	Fgfr2	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0082706	Bone morphogenetic protein 4.	Fibroblast growth factor receptor 2 isoform X1.	0.529
Bmp4	Foxa2	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0055070	Bone morphogenetic protein 4.	Forkhead box protein A2, hepatocyte nuclear factor 3-beta.	0.559
Bmp4	Foxf1	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0086275	Bone morphogenetic protein 4.	Forkhead box protein F1.	0.731
Bmp4	Gata4	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0037095	Bone morphogenetic protein 4.	Transcription factor GATA-4.	0.808
Bmp4	Igf1	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0024389	Bone morphogenetic protein 4.	Insulin-like growth factor I isoform X1.	0.538
Bmp4	Lif	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0025425	Bone morphogenetic protein 4.	Leukemia inhibitory factor isoform X1.	0.567
Bmp4	Nkx2-1	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0032303	Bone morphogenetic protein 4.	Homeobox protein Nkx-2.1 isoform X1.	0.451
Bmp4	Nog	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0029156	Bone morphogenetic protein 4.	Noggin.	0.998
Bmp4	Pitx2	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0060461	Bone morphogenetic protein 4.	Paired-like homeodomain transcription factor 2.	0.501
Bmp4	Shh	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0067069	Bone morphogenetic protein 4.	Sonic hedgehog protein isoform X1.	0.690
Bmp4	Sox2	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0057315	Bone morphogenetic protein 4.	Transcription factor SOX2 (SOX group B).	0.647
Bmp4	Sox9	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0030751	Bone morphogenetic protein 4.	Transcription factor SOX9 (SOX group E).	0.582
Bmp4	Tgfbr2	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0090480	Bone morphogenetic protein 4.	TGF-beta receptor type-2 isoform X1.	0.671
Bmp4	Wnt2	MGP_CAROLIEiJ_P0036330	MGP_CAROLIEiJ_P0072724	Bone morphogenetic protein 4.	Wingless-type MMTV integration site family, member 2.	0.686
Celsr1	Vangl2	MGP_CAROLIEiJ_P0039361	MGP_CAROLIEiJ_P0021246	Cadherin EGF LAG seven-pass G-type receptor 1.	Vang-like protein 2 isoform X1.	0.779
Cfc1	Nodal	MGP_CAROLIEiJ_P0017056	MGP_CAROLIEiJ_P0023053	Cryptic protein.	Nodal homolog.	0.486