(46 nodes) E-box binding network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Myc	Myc proto-oncogene protein. (454 aa)
	Tcf12	Transcription factor 12 isoform X1. (706 aa)
	Hand2	Heart- and neural crest derivatives-expressed protein 2. (217 aa)
	Ascl2	Achaete-scute complex protein. (263 aa)
	Arntl	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1. (626 aa)
	Myod1	Myoblast determination protein 1. (318 aa)
	Arntl2	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1. (569 aa)
	Bhlhe41	Class E basic helix-loop-helix protein 41. (410 aa)
	Pparg	Peroxisome proliferator-activated receptor gamma isoform X1. (505 aa)
	Bhlhe40	Class E basic helix-loop-helix protein 40. (409 aa)
	Mitf	Microphthalmia-associated transcription factor isoform X1. (526 aa)
	MGP_CAROLIEiJ_P0074743	annotation not available (143 aa)
	Atoh8	Protein atonal homolog 8. (322 aa)
	Clock	Circadian locomoter output cycles protein kaput isoform X1. (857 aa)
	Hes3	Hairy and enhancer of split 3. (197 aa)
	Hdac1	Histone deacetylase 1/2. (482 aa)
	Tal1	T-cell acute lymphocytic leukemia protein 1. (329 aa)
	Neurog2	Neurogenin 2. (263 aa)
	Ciart	Circadian-associated transcriptional repressor. (185 aa)
	Snai1	Zinc finger protein SNAI1. (264 aa)
	Tcf15	Transcription factor 15. (195 aa)
	Neurod1	Neurogenic differentiation factor 1. (357 aa)
	Ptf1a	Pancreas transcription factor 1 subunit alpha. (324 aa)
	Gata3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (443 aa)
	Tcf4	Transcription factor 4 isoform X1. (670 aa)
	Zeb1	Zinc finger E-box-binding homeobox 1. (1114 aa)
	Hes1	Hairy and enhancer of split 1. (281 aa)
	Snai2	Zinc finger protein SNAI2. (269 aa)
	Tfap4	Transcription factor AP-4 isoform X1. (338 aa)
	Srebf2	Sterol regulatory element-binding transcription factor 2. (1130 aa)
	Scx	Basic helix-loop-helix transcription factor scleraxis. (207 aa)
	Prmt5	Protein arginine N-methyltransferase 5. (595 aa)
	Neurog1	Neurogenin 1. (244 aa)
	MGP_CAROLIEiJ_P0032621	annotation not available (299 aa)
	Hif1a	Hypoxia-inducible factor 1-alpha isoform X1. (839 aa)
	Ahr	Aryl hydrocarbon receptor. (854 aa)
	Twist1	Twist-related protein 1. (206 aa)
	Nr1d1	Nuclear receptor subfamily 1 group D member 1. (619 aa)
	Neurod2	Neurogenic differentiation factor 2. (383 aa)
	Mybbp1a	Myb-binding protein 1A. (1345 aa)
	Per1	Period circadian protein homolog 1. (1291 aa)
	Ascl1	Achaete-scute complex protein. (231 aa)
	Cry1	Cryptochrome-1. (606 aa)
	Tcf3	Transcription factor E2-alpha isoform X1. (653 aa)
	Tcf21	Transcription factor 21. (179 aa)
	Myog	Myogenic factor 4 (myogenin). (224 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ahr	Arntl	MGP_CAROLIEiJ_P0032141	MGP_CAROLIEiJ_P0081625	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	0.792
Ahr	Arntl2	MGP_CAROLIEiJ_P0032141	MGP_CAROLIEiJ_P0076880	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	0.786
Ahr	Clock	MGP_CAROLIEiJ_P0032141	MGP_CAROLIEiJ_P0068714	Aryl hydrocarbon receptor.	Circadian locomoter output cycles protein kaput isoform X1.	0.648
Arntl	Ahr	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0032141	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Aryl hydrocarbon receptor.	0.792
Arntl	Arntl2	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0076880	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	0.870
Arntl	Bhlhe40	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0075293	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Class E basic helix-loop-helix protein 40.	0.757
Arntl	Bhlhe41	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0076826	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Class E basic helix-loop-helix protein 41.	0.753
Arntl	Ciart	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0059252	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Circadian-associated transcriptional repressor.	0.689
Arntl	Clock	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0068714	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Circadian locomoter output cycles protein kaput isoform X1.	0.999
Arntl	Cry1	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0024322	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Cryptochrome-1.	0.999
Arntl	Hif1a	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0032540	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Hypoxia-inducible factor 1-alpha isoform X1.	0.866
Arntl	Nr1d1	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0029707	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Nuclear receptor subfamily 1 group D member 1.	0.775
Arntl	Per1	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0027482	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Period circadian protein homolog 1.	0.996
Arntl	Pparg	MGP_CAROLIEiJ_P0081625	MGP_CAROLIEiJ_P0075565	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	Peroxisome proliferator-activated receptor gamma isoform X1.	0.581
Arntl2	Ahr	MGP_CAROLIEiJ_P0076880	MGP_CAROLIEiJ_P0032141	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	Aryl hydrocarbon receptor.	0.786
Arntl2	Arntl	MGP_CAROLIEiJ_P0076880	MGP_CAROLIEiJ_P0081625	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1.	0.870
Arntl2	Bhlhe40	MGP_CAROLIEiJ_P0076880	MGP_CAROLIEiJ_P0075293	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	Class E basic helix-loop-helix protein 40.	0.480
Arntl2	Bhlhe41	MGP_CAROLIEiJ_P0076880	MGP_CAROLIEiJ_P0076826	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	Class E basic helix-loop-helix protein 41.	0.500
Arntl2	Clock	MGP_CAROLIEiJ_P0076880	MGP_CAROLIEiJ_P0068714	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	Circadian locomoter output cycles protein kaput isoform X1.	0.955
Arntl2	Cry1	MGP_CAROLIEiJ_P0076880	MGP_CAROLIEiJ_P0024322	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1.	Cryptochrome-1.	0.855