(68 nodes) Adipocytokine signaling pathway network (Mus caroli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Prkag3	5'-AMP-activated protein kinase subunit gamma-3 isoform X1. (489 aa)
	Acsl3	Long-chain-fatty-acid--CoA ligase 3. (720 aa)
	Irs1	Insulin receptor substrate 1. (1230 aa)
	Rxrg	Retinoic acid receptor RXR-gamma isoform X1. (463 aa)
	Akt3	RAC-gamma serine/threonine-protein kinase. (479 aa)
	Stk11	Serine/threonine-protein kinase STK11 isoform X1. (441 aa)
	Mapk9	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase). (423 aa)
	Acsl6	Long-chain-fatty-acid--CoA ligase 6 isoform X1. (722 aa)
	Slc2a4	MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4. (509 aa)
	Stat3	Signal transducer and activator of transcription 3 isoform X1. (770 aa)
	G6pc	Glucose-6-phosphatase. (357 aa)
	G6pc3	Glucose-6-phosphatase 3. (346 aa)
	Socs3	Suppressor of cytokine signaling 3. (225 aa)
	Pomc	Pro-opiomelanocortin. (235 aa)
	Nfkbia	NF-kappa-B inhibitor alpha. (314 aa)
	Akt1	RAC-alpha serine/threonine-protein kinase isoform X1. (480 aa)
	Mapk8	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase). (427 aa)
	Pck2	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (667 aa)
	Prkaa1	5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1. (559 aa)
	Ppara	Peroxisome proliferator-activated receptor alpha. (468 aa)
	Cpt1b	Carnitine O-palmitoyltransferase 1, muscle isoform. (772 aa)
	Prkag1	5'-AMP-activated protein kinase, regulatory gamma subunit. (330 aa)
	Adipoq	Adiponectin. (247 aa)
	Rxrb	Retinoic acid receptor RXR-beta isoform X1. (527 aa)
	Tnf	Tumor necrosis factor superfamily, member 2. (235 aa)
	Nfkbie	NF-kappa-B inhibitor epsilon isoform X1. (364 aa)
	Acsbg2	Long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1. (667 aa)
	Acsbg3	Long-chain-fatty-acid--CoA ligase ACSBG2-like isoform X1. (703 aa)
	Cpt1a	Carnitine O-palmitoyltransferase 1, liver isoform. (773 aa)
	Rela	Transcription factor p65. (549 aa)
	Jak2	Tyrosine-protein kinase JAK2. (1132 aa)
	Chuk	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
	Acsl5	Long-chain-fatty-acid--CoA ligase 5 isoform X1. (683 aa)
	Prkcq	Protein kinase C theta type isoform X1. (707 aa)
	Traf2	TNF receptor-associated factor 2 isoform X1. (508 aa)
	Rxra	Retinoic acid receptor RXR-alpha isoform X1. (457 aa)
	G6pc2	Glucose-6-phosphatase 2 isoform X1. (356 aa)
	Pck1	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
	Nfkb1	Nuclear factor NF-kappa-B p105 subunit. (971 aa)
	Lepr	Leptin receptor isoform X1. (1162 aa)
	Prkaa2	5'-AMP-activated protein kinase catalytic subunit alpha-2. (552 aa)
	Slc2a1	MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1. (492 aa)
	Tnfrsf1b	Tumor necrosis factor receptor superfamily member 1B. (474 aa)
	Mtor	Serine/threonine-protein kinase mTOR. (2549 aa)
	Cd36	Platelet glycoprotein 4. (472 aa)
	Prkag2	5'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa)
	Ppargc1a	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
	Mapk10	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase). (494 aa)
	Acacb	Acetyl-CoA carboxylase / biotin carboxylase 2. (2423 aa)
	Prkab1	5'-AMP-activated protein kinase, regulatory beta subunit. (270 aa)
	Ptpn11	Tyrosine-protein phosphatase non-receptor type 11 isoform X1. (597 aa)
	Camkk2	Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (588 aa)
	Irs3	Insulin receptor substrate 1-like. (494 aa)
	Lep	Leptin. (167 aa)
	Npy	Pro-neuropeptide Y. (97 aa)
	Adipor2	Adiponectin receptor protein 2. (346 aa)
	Tnfrsf1a	Tumor necrosis factor receptor superfamily member 1A. (452 aa)
	Akt2	RAC-beta serine/threonine-protein kinase. (481 aa)
	Nfkbib	NF-kappa-B inhibitor beta. (359 aa)
	Cpt1c	Carnitine O-palmitoyltransferase 1, brain isoform isoform X1. (798 aa)
	Irs2	Insulin receptor substrate 2. (1324 aa)
	Ikbkb	Inhibitor of nuclear factor kappa-B kinase subunit beta. (35 aa)
	Acsl1	Long-chain-fatty-acid--CoA ligase 1. (699 aa)
	Tradd	Tumor necrosis factor receptor type 1-associated DEATH domain protein. (310 aa)
	Agrp	Agouti related protein. (131 aa)
	Acsbg1	Long-chain-fatty-acid--CoA ligase ACSBG1. (721 aa)
	Irs4	Insulin receptor substrate 4. (1217 aa)
	Acsl4	Long-chain-fatty-acid--CoA ligase 4 isoform X1. (711 aa)

Your Current Organism:

Mus caroli

NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acacb	Acsl1	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0084373	Acetyl-CoA carboxylase / biotin carboxylase 2.	Long-chain-fatty-acid--CoA ligase 1.	0.535
Acacb	Acsl3	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0018602	Acetyl-CoA carboxylase / biotin carboxylase 2.	Long-chain-fatty-acid--CoA ligase 3.	0.401
Acacb	Acsl4	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0092892	Acetyl-CoA carboxylase / biotin carboxylase 2.	Long-chain-fatty-acid--CoA ligase 4 isoform X1.	0.401
Acacb	Cd36	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0066748	Acetyl-CoA carboxylase / biotin carboxylase 2.	Platelet glycoprotein 4.	0.425
Acacb	Cpt1a	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0047331	Acetyl-CoA carboxylase / biotin carboxylase 2.	Carnitine O-palmitoyltransferase 1, liver isoform.	0.953
Acacb	Cpt1b	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0039479	Acetyl-CoA carboxylase / biotin carboxylase 2.	Carnitine O-palmitoyltransferase 1, muscle isoform.	0.943
Acacb	Cpt1c	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0079411	Acetyl-CoA carboxylase / biotin carboxylase 2.	Carnitine O-palmitoyltransferase 1, brain isoform isoform X1.	0.936
Acacb	Ppara	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0039338	Acetyl-CoA carboxylase / biotin carboxylase 2.	Peroxisome proliferator-activated receptor alpha.	0.502
Acacb	Ppargc1a	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0068146	Acetyl-CoA carboxylase / biotin carboxylase 2.	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1.	0.412
Acacb	Prkaa1	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0037745	Acetyl-CoA carboxylase / biotin carboxylase 2.	5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1.	0.932
Acacb	Prkaa2	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0063258	Acetyl-CoA carboxylase / biotin carboxylase 2.	5'-AMP-activated protein kinase catalytic subunit alpha-2.	0.938
Acacb	Prkab1	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0070216	Acetyl-CoA carboxylase / biotin carboxylase 2.	5'-AMP-activated protein kinase, regulatory beta subunit.	0.916
Acacb	Prkag1	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0039715	Acetyl-CoA carboxylase / biotin carboxylase 2.	5'-AMP-activated protein kinase, regulatory gamma subunit.	0.910
Acacb	Prkag2	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0067006	Acetyl-CoA carboxylase / biotin carboxylase 2.	5'-AMP-activated protein kinase subunit gamma-2 isoform X1.	0.921
Acacb	Prkag3	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0018361	Acetyl-CoA carboxylase / biotin carboxylase 2.	5'-AMP-activated protein kinase subunit gamma-3 isoform X1.	0.912
Acacb	Slc2a4	MGP_CAROLIEiJ_P0069975	MGP_CAROLIEiJ_P0027695	Acetyl-CoA carboxylase / biotin carboxylase 2.	MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4.	0.423
Acsbg1	Acsbg2	MGP_CAROLIEiJ_P0087907	MGP_CAROLIEiJ_P0045383	Long-chain-fatty-acid--CoA ligase ACSBG1.	Long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1.	0.613
Acsbg1	Acsbg3	MGP_CAROLIEiJ_P0087907	MGP_CAROLIEiJ_P0045384	Long-chain-fatty-acid--CoA ligase ACSBG1.	Long-chain-fatty-acid--CoA ligase ACSBG2-like isoform X1.	0.623
Acsbg1	Acsl1	MGP_CAROLIEiJ_P0087907	MGP_CAROLIEiJ_P0084373	Long-chain-fatty-acid--CoA ligase ACSBG1.	Long-chain-fatty-acid--CoA ligase 1.	0.663
Acsbg1	Acsl3	MGP_CAROLIEiJ_P0087907	MGP_CAROLIEiJ_P0018602	Long-chain-fatty-acid--CoA ligase ACSBG1.	Long-chain-fatty-acid--CoA ligase 3.	0.757