node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Anxa4 | Capg | ENSMUSP00000109305 | ENSMUSP00000109705 | Annexin A4; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | 0.575 |
Capg | Anxa4 | ENSMUSP00000109705 | ENSMUSP00000109305 | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | Annexin A4; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. | 0.575 |
Capg | Cstb | ENSMUSP00000109705 | ENSMUSP00000005185 | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | Cystatin-B; This is an intracellular thiol proteinase inhibitor. | 0.414 |
Capg | Emp3 | ENSMUSP00000109705 | ENSMUSP00000132519 | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. | 0.500 |
Capg | Fxyd5 | ENSMUSP00000109705 | ENSMUSP00000009831 | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | 0.407 |
Cstb | Capg | ENSMUSP00000005185 | ENSMUSP00000109705 | Cystatin-B; This is an intracellular thiol proteinase inhibitor. | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | 0.414 |
Emp3 | Capg | ENSMUSP00000132519 | ENSMUSP00000109705 | Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | 0.500 |
Emp3 | Fxyd5 | ENSMUSP00000132519 | ENSMUSP00000009831 | Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | 0.646 |
Emp3 | Lgals1 | ENSMUSP00000132519 | ENSMUSP00000086795 | Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. | 0.736 |
Fxyd5 | Capg | ENSMUSP00000009831 | ENSMUSP00000109705 | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | Macrophage-capping protein; Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Uncapping occurs either when Ca(2+) falls or when the concentration of polyphosphoinositide rises, both at low and high Ca(2+); Belongs to the villin/gelsolin family. | 0.407 |
Fxyd5 | Emp3 | ENSMUSP00000009831 | ENSMUSP00000132519 | FXYD domain-containing ion transport regulator 5; Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). | Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. | 0.646 |
Lgals1 | Emp3 | ENSMUSP00000086795 | ENSMUSP00000132519 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. | Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. | 0.736 |
Lgals1 | Lgals2 | ENSMUSP00000086795 | ENSMUSP00000036598 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. | Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known. | 0.752 |
Lgals2 | Lgals1 | ENSMUSP00000036598 | ENSMUSP00000086795 | Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known. | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. | 0.752 |