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H2ac4 H2ac4 H2bc8 H2bc8 Hist1h2ap Hist1h2ap H2ac7 H2ac7 H2ac13 H2ac13 H2ac11 H2ac11 Hist1h2ao Hist1h2ao Hist1h2an Hist1h2an H4c1 H4c1 H4c2 H4c2 H4c3 H4c3 H4c4 H4c4 H2ac8 H2ac8 H4c6 H4c6 H4c8 H4c8 H4c9 H4c9 Hist1h4n Hist1h4n H4c12 H4c12 H2ac6 H2ac6 H4c14 H4c14 H2bc18 H2bc18 H4f16 H4f16 H3c11 H3c11 H3c10 H3c10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ac4Histone H2A type 1-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (130 aa)
H2bc8H2B clustered histone 8. (126 aa)
Hist1h2apHistone cluster 1, H2ap. (130 aa)
H2ac7H2A clustered histone 7. (130 aa)
H2ac13H2A clustered histone 13. (130 aa)
H2ac11H2A clustered histone 11. (130 aa)
Hist1h2aoHistone cluster 1, H2ao. (130 aa)
Hist1h2anHistone cluster 1, H2an. (130 aa)
H4c1H4 clustered histone 1. (103 aa)
H4c2H4 clustered histone 2. (103 aa)
H4c3H4 clustered histone 3. (103 aa)
H4c4H4 clustered histone 4. (103 aa)
H2ac8H2A clustered histone 8. (130 aa)
H4c6H4 clustered histone 6. (103 aa)
H4c8H4 clustered histone 8. (103 aa)
H4c9H4 clustered histone 9. (103 aa)
Hist1h4nHistone cluster 1, H4n. (103 aa)
H4c12H4 clustered histone 12. (103 aa)
H2ac6H2A clustered histone 6. (130 aa)
H4c14H4 clustered histone 14. (103 aa)
H2bc18Histone H2B type 2-B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa)
H4f16H4 histone 16. (103 aa)
H3c11H3 clustered histone 11. (136 aa)
H3c10H3 clustered histone 10. (136 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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