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| Actr6 | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. (396 aa) | ||||
| H2az1 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] (128 aa) | ||||
| Znhit1 | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. (158 aa) | ||||
| Anp32e | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] (260 aa) | ||||
| Srcap | Snf2-related CREBBP activator protein. (3271 aa) | ||||
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Actr6 | Anp32e | ENSMUSP00000020109 | ENSMUSP00000128483 | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | 0.612 |
| Actr6 | H2az1 | ENSMUSP00000020109 | ENSMUSP00000036907 | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.874 |
| Actr6 | Srcap | ENSMUSP00000020109 | ENSMUSP00000140036 | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | Snf2-related CREBBP activator protein. | 0.943 |
| Actr6 | Znhit1 | ENSMUSP00000020109 | ENSMUSP00000106720 | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | 0.941 |
| Anp32e | Actr6 | ENSMUSP00000128483 | ENSMUSP00000020109 | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | 0.612 |
| Anp32e | H2az1 | ENSMUSP00000128483 | ENSMUSP00000036907 | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.897 |
| Anp32e | Srcap | ENSMUSP00000128483 | ENSMUSP00000140036 | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | Snf2-related CREBBP activator protein. | 0.759 |
| Anp32e | Znhit1 | ENSMUSP00000128483 | ENSMUSP00000106720 | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | 0.568 |
| H2az1 | Actr6 | ENSMUSP00000036907 | ENSMUSP00000020109 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | 0.874 |
| H2az1 | Anp32e | ENSMUSP00000036907 | ENSMUSP00000128483 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | 0.897 |
| H2az1 | Srcap | ENSMUSP00000036907 | ENSMUSP00000140036 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | Snf2-related CREBBP activator protein. | 0.879 |
| H2az1 | Znhit1 | ENSMUSP00000036907 | ENSMUSP00000106720 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | 0.764 |
| Srcap | Actr6 | ENSMUSP00000140036 | ENSMUSP00000020109 | Snf2-related CREBBP activator protein. | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | 0.943 |
| Srcap | Anp32e | ENSMUSP00000140036 | ENSMUSP00000128483 | Snf2-related CREBBP activator protein. | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | 0.759 |
| Srcap | H2az1 | ENSMUSP00000140036 | ENSMUSP00000036907 | Snf2-related CREBBP activator protein. | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.879 |
| Srcap | Znhit1 | ENSMUSP00000140036 | ENSMUSP00000106720 | Snf2-related CREBBP activator protein. | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | 0.911 |
| Znhit1 | Actr6 | ENSMUSP00000106720 | ENSMUSP00000020109 | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | Actin-related protein 6; Belongs to the actin family. ARP6 subfamily. | 0.941 |
| Znhit1 | Anp32e | ENSMUSP00000106720 | ENSMUSP00000128483 | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] | 0.568 |
| Znhit1 | H2az1 | ENSMUSP00000106720 | ENSMUSP00000036907 | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.764 |
| Znhit1 | Srcap | ENSMUSP00000106720 | ENSMUSP00000140036 | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | Snf2-related CREBBP activator protein. | 0.911 |