(12 nodes) Mixed, incl. Glycylpeptide N-tetradecanoyltransferase, and AP-4 complex accessory subunit RUSC1, RUN domain network (Mus musculus)

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second shell of interactors

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Your Input:
	Rundc3a	RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family. (446 aa)
	Slc25a39	Solute carrier family 25 member 39; Required for normal heme biosynthesis; Belongs to the mitochondrial carrier (TC 2.A.29) family. (359 aa)
	Dcakd	Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. (231 aa)
	Nmt1	Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. (496 aa)
	Acbd4	Acyl-Coenzyme A-binding domain-containing 4. (327 aa)
	Abtb1	Ankyrin repeat and BTB/POZ domain-containing protein 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes (By similarity). (478 aa)
	Crebl2	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. (123 aa)
	Acbd6	Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity). (282 aa)
	Nmt2	Glycylpeptide N-tetradecanoyltransferase 2; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. (529 aa)
	Rusc1	RUN and SH3 domain-containing protein 1; Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. (1030 aa)
	Tmub2	Transmembrane and ubiquitin-like domain-containing protein 2. (319 aa)
	Gm43738	Predicted gene 43738. (862 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acbd4	Acbd6	ENSMUSP00000024492	ENSMUSP00000049124	Acyl-Coenzyme A-binding domain-containing 4.	Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity).	0.414
Acbd4	Crebl2	ENSMUSP00000024492	ENSMUSP00000035304	Acyl-Coenzyme A-binding domain-containing 4.	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.	0.436
Acbd4	Gm43738	ENSMUSP00000024492	ENSMUSP00000142694	Acyl-Coenzyme A-binding domain-containing 4.	Predicted gene 43738.	0.409
Acbd4	Rusc1	ENSMUSP00000024492	ENSMUSP00000088447	Acyl-Coenzyme A-binding domain-containing 4.	RUN and SH3 domain-containing protein 1; Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.	0.480
Acbd6	Acbd4	ENSMUSP00000049124	ENSMUSP00000024492	Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity).	Acyl-Coenzyme A-binding domain-containing 4.	0.414
Acbd6	Nmt1	ENSMUSP00000049124	ENSMUSP00000021314	Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity).	Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.	0.734
Acbd6	Nmt2	ENSMUSP00000049124	ENSMUSP00000080600	Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity).	Glycylpeptide N-tetradecanoyltransferase 2; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.	0.873
Crebl2	Acbd4	ENSMUSP00000035304	ENSMUSP00000024492	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.	Acyl-Coenzyme A-binding domain-containing 4.	0.436
Crebl2	Gm43738	ENSMUSP00000035304	ENSMUSP00000142694	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.	Predicted gene 43738.	0.475
Crebl2	Rusc1	ENSMUSP00000035304	ENSMUSP00000088447	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.	RUN and SH3 domain-containing protein 1; Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.	0.516
Dcakd	Nmt1	ENSMUSP00000021313	ENSMUSP00000021314	Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family.	Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.	0.779
Dcakd	Rundc3a	ENSMUSP00000021313	ENSMUSP00000006750	Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family.	RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family.	0.661
Dcakd	Slc25a39	ENSMUSP00000021313	ENSMUSP00000018821	Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family.	Solute carrier family 25 member 39; Required for normal heme biosynthesis; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.630
Dcakd	Tmub2	ENSMUSP00000021313	ENSMUSP00000116327	Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family.	Transmembrane and ubiquitin-like domain-containing protein 2.	0.663
Gm43738	Acbd4	ENSMUSP00000142694	ENSMUSP00000024492	Predicted gene 43738.	Acyl-Coenzyme A-binding domain-containing 4.	0.409
Gm43738	Crebl2	ENSMUSP00000142694	ENSMUSP00000035304	Predicted gene 43738.	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.	0.475
Gm43738	Rundc3a	ENSMUSP00000142694	ENSMUSP00000006750	Predicted gene 43738.	RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family.	0.827
Nmt1	Acbd6	ENSMUSP00000021314	ENSMUSP00000049124	Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.	Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity).	0.734
Nmt1	Dcakd	ENSMUSP00000021314	ENSMUSP00000021313	Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.	Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family.	0.779
Nmt1	Rundc3a	ENSMUSP00000021314	ENSMUSP00000006750	Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.	RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family.	0.615