(7 nodes) Bax inhibitor 1-related, and Niban-like network (Mus musculus)

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second shell of interactors

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Your Input:
	Grina	Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily. (345 aa)
	Tmbim6	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation. (237 aa)
	Fam129b	Protein Niban 2; May play a role in apoptosis suppression. (749 aa)
	Cbarp	Voltage-dependent calcium channel beta subunit-associated regulatory protein; Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis. (698 aa)
	Tmbim1	Protein lifeguard 3; Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily. (309 aa)
	Ghitm	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity). (346 aa)
	Rmdn2	Regulator of microtubule dynamics protein 2; Belongs to the RMDN family. (410 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cbarp	Ghitm	ENSMUSP00000101008	ENSMUSP00000129712	Voltage-dependent calcium channel beta subunit-associated regulatory protein; Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis.	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	0.584
Cbarp	Rmdn2	ENSMUSP00000101008	ENSMUSP00000153443	Voltage-dependent calcium channel beta subunit-associated regulatory protein; Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis.	Regulator of microtubule dynamics protein 2; Belongs to the RMDN family.	0.598
Ghitm	Cbarp	ENSMUSP00000129712	ENSMUSP00000101008	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	Voltage-dependent calcium channel beta subunit-associated regulatory protein; Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis.	0.584
Ghitm	Grina	ENSMUSP00000129712	ENSMUSP00000023225	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.	0.688
Ghitm	Tmbim1	ENSMUSP00000129712	ENSMUSP00000109427	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	Protein lifeguard 3; Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily.	0.705
Ghitm	Tmbim6	ENSMUSP00000129712	ENSMUSP00000023749	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.	0.700
Grina	Ghitm	ENSMUSP00000023225	ENSMUSP00000129712	Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	0.688
Grina	Tmbim6	ENSMUSP00000023225	ENSMUSP00000023749	Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.	0.736
Rmdn2	Cbarp	ENSMUSP00000153443	ENSMUSP00000101008	Regulator of microtubule dynamics protein 2; Belongs to the RMDN family.	Voltage-dependent calcium channel beta subunit-associated regulatory protein; Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis.	0.598
Tmbim1	Ghitm	ENSMUSP00000109427	ENSMUSP00000129712	Protein lifeguard 3; Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily.	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	0.705
Tmbim1	Tmbim6	ENSMUSP00000109427	ENSMUSP00000023749	Protein lifeguard 3; Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily.	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.	0.634
Tmbim6	Ghitm	ENSMUSP00000023749	ENSMUSP00000129712	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.	Growth hormone-inducible transmembrane protein; Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity).	0.700
Tmbim6	Grina	ENSMUSP00000023749	ENSMUSP00000023225	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.	Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.	0.736
Tmbim6	Tmbim1	ENSMUSP00000023749	ENSMUSP00000109427	Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling (By similarity). Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.	Protein lifeguard 3; Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily.	0.634