STRINGSTRING
Brinp2 Brinp2 Brinp3 Brinp3 Tafa3 Tafa3 Nxph1 Nxph1 Gm5849 Gm5849 Astn1 Astn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Brinp2BMP/retinoic acid-inducible neural-specific protein 2; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition; Belongs to the BRINP family. (783 aa)
Brinp3BMP/retinoic acid-inducible neural-specific protein 3; Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development. Belongs to the BRINP family. (766 aa)
Tafa3Chemokine-like protein TAFA-3; Plays a role in the regulation of microglia polarization. Belongs to the TAFA family. (132 aa)
Nxph1Neurexophilin-1; May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins; Belongs to the neurexophilin family. (271 aa)
Gm5849Predicted gene 5849; Belongs to the S-100 family. (117 aa)
Astn1Astrotactin-1; Neuronal adhesion molecule that is required for normal migration of young postmitotic neuroblasts along glial fibers, especially in the cerebellum. Required for normal rate of migration of granule cells during brain development and for normal cerebellum development. (1302 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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