(6 nodes) Mixed, incl. GRAF family, and Dienelactone hydrolase family network (Mus musculus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Dner	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. (737 aa)
	Arhgap26	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42. (814 aa)
	Iglon5	IgLON family member 5. (336 aa)
	Dpp10	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable). (800 aa)
	Arhgap26-2	Rho GTPase-activating protein 26. (170 aa)
	Dennd2c	DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. (920 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arhgap26	Dennd2c	ENSMUSP00000095200	ENSMUSP00000127187	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	0.500
Arhgap26	Dner	ENSMUSP00000095200	ENSMUSP00000042927	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	0.614
Arhgap26	Dpp10	ENSMUSP00000095200	ENSMUSP00000108225	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	0.496
Arhgap26	Iglon5	ENSMUSP00000095200	ENSMUSP00000103608	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	IgLON family member 5.	0.484
Arhgap26-2	Dennd2c	ENSMUSP00000121894	ENSMUSP00000127187	Rho GTPase-activating protein 26.	DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	0.500
Arhgap26-2	Dner	ENSMUSP00000121894	ENSMUSP00000042927	Rho GTPase-activating protein 26.	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	0.614
Arhgap26-2	Dpp10	ENSMUSP00000121894	ENSMUSP00000108225	Rho GTPase-activating protein 26.	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	0.480
Arhgap26-2	Iglon5	ENSMUSP00000121894	ENSMUSP00000103608	Rho GTPase-activating protein 26.	IgLON family member 5.	0.484
Dennd2c	Arhgap26	ENSMUSP00000127187	ENSMUSP00000095200	DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	0.500
Dennd2c	Arhgap26-2	ENSMUSP00000127187	ENSMUSP00000121894	DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	Rho GTPase-activating protein 26.	0.500
Dner	Arhgap26	ENSMUSP00000042927	ENSMUSP00000095200	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	0.614
Dner	Arhgap26-2	ENSMUSP00000042927	ENSMUSP00000121894	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	Rho GTPase-activating protein 26.	0.614
Dner	Dpp10	ENSMUSP00000042927	ENSMUSP00000108225	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	0.694
Dner	Iglon5	ENSMUSP00000042927	ENSMUSP00000103608	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	IgLON family member 5.	0.651
Dpp10	Arhgap26	ENSMUSP00000108225	ENSMUSP00000095200	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	0.496
Dpp10	Arhgap26-2	ENSMUSP00000108225	ENSMUSP00000121894	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	Rho GTPase-activating protein 26.	0.480
Dpp10	Dner	ENSMUSP00000108225	ENSMUSP00000042927	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling.	0.694
Dpp10	Iglon5	ENSMUSP00000108225	ENSMUSP00000103608	Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).	IgLON family member 5.	0.847
Iglon5	Arhgap26	ENSMUSP00000103608	ENSMUSP00000095200	IgLON family member 5.	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42.	0.484
Iglon5	Arhgap26-2	ENSMUSP00000103608	ENSMUSP00000121894	IgLON family member 5.	Rho GTPase-activating protein 26.	0.484