STRINGSTRING
Ms4a8a Ms4a8a Dusp18 Dusp18 Nxph3 Nxph3 Fam57b Fam57b Ptpn21 Ptpn21 Gm5127 Gm5127
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ms4a8aMembrane-spanning 4-domains subfamily A member 8; May be involved in signal transduction as a component of a multimeric receptor complex. (290 aa)
Dusp18Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). (188 aa)
Nxph3Neurexophilin-3; May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins; Belongs to the neurexophilin family. (252 aa)
Fam57bCeramide synthase; Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. (275 aa)
Ptpn21Tyrosine-protein phosphatase non-receptor type 21; May be involved in the regulation of growth and differentiation of liver cells; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1176 aa)
Gm5127Predicted gene, EG331493. (212 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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