STRINGSTRING
Spdye4b Spdye4b Angptl6 Angptl6 Shfl Shfl Adamts15 Adamts15 Thsd1 Thsd1 Spdye4a Spdye4a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Spdye4bSpeedy/RINGO cell cycle regulator family, member E4B. (236 aa)
Angptl6Angiopoietin-related protein 6; May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure. (457 aa)
ShflShiftless antiviral inhibitor of ribosomal frameshifting protein homolog; Inhibits programmed -1 ribosomal frameshifting (-1PRF) of a variety of mRNAs from viruses and cellular genes. Interacts with the -1PRF signal of target mRNA and translating ribosomes and causes premature translation termination at the frameshifting site. May exhibit antiviral activity; Belongs to the SHFL family. (290 aa)
Adamts15A disintegrin and metalloproteinase with thrombospondin motifs 15. (950 aa)
Thsd1Thrombospondin type-1 domain-containing protein 1. (851 aa)
Spdye4aSpeedy protein E4A; Promotes progression through the cell cycle via binding and activation of CDK1; Belongs to the Speedy/Ringo family. (268 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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