STRINGSTRING
Wfdc18 Wfdc18 Fstl5 Fstl5 Fstl4 Fstl4 Spint3 Spint3 Spint5 Spint5 Chrdl2 Chrdl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Wfdc18WAP four-disulfide core domain protein 18; Could have proteinase inhibiting capacity. (74 aa)
Fstl5Follistatin-related protein 5. (847 aa)
Fstl4Follistatin-related protein 4. (841 aa)
Spint3Serine peptidase inhibitor, Kunitz type, 3. (88 aa)
Spint5Serine protease inhibitor, Kunitz type 5. (105 aa)
Chrdl2Chordin-like protein 2; Implicated in tumor angiogenesis (By similarity). May inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. May play a role during myoblast and osteoblast differentiation, and maturation. (433 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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