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Krt2 Krt2 Krt82 Krt82 Krt84 Krt84 Krt79 Krt79 Krt75 Krt75 Krt81 Krt81 Krt73 Krt73 Krt72 Krt72 Krt77 Krt77 Krt86 Krt86
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Krt2Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. (707 aa)
Krt82Keratin, type II cuticular Hb2; Belongs to the intermediate filament family. (516 aa)
Krt84Keratin, type II cuticular Hb4; Belongs to the intermediate filament family. (603 aa)
Krt79Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. (531 aa)
Krt75Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle (By similarity). (551 aa)
Krt81Keratin, type II cuticular Hb1. (481 aa)
Krt73Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity). (539 aa)
Krt72Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (By similarity). (520 aa)
Krt77Keratin, type II cytoskeletal 1b. (572 aa)
Krt86Keratin, type II cuticular Hb6; Belongs to the intermediate filament family. (486 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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