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Defb1 Defb1 Defb14 Defb14 Defa39 Defa39 Defa26 Defa26 Defa34 Defa34 Defa21 Defa21 Defa38 Defa38 Defa35 Defa35 Defa17 Defa17 Defa24 Defa24 Defb4 Defb4 Defa37 Defa37 Defa20 Defa20 Defa25 Defa25 Defa28 Defa28 Defa29 Defa29 Defa5 Defa5 Defa3 Defa3 Defa40 Defa40 Defa31 Defa31 Defa22 Defa22 Defa30 Defa30 Defa23 Defa23 Defa43 Defa43 Defa41 Defa41 AY761185 AY761185 Mptx2 Mptx2 Defa27 Defa27
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Defb1Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. (69 aa)
Defb14Beta-defensin 14; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa)
Defa39Defensin, alpha, 39. (116 aa)
Defa26Alpha-defensin 26; May have microbicidal activities; Belongs to the alpha-defensin family. (93 aa)
Defa34Defensin, alpha, 34. (93 aa)
Defa21Alpha-defensin 21; May have microbicidal activities; Belongs to the alpha-defensin family. (93 aa)
Defa38Defensin, alpha, 38. (116 aa)
Defa35Alpha-defensin 5; Probably contributes to the antimicrobial barrier function of the small bowel mucosa; Belongs to the alpha-defensin family. (93 aa)
Defa17Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa. (93 aa)
Defa24Alpha-defensin 24; May have microbicidal activities; Belongs to the alpha-defensin family. (93 aa)
Defb4Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. (63 aa)
Defa37Defensin, alpha, 36. (93 aa)
Defa20Defensin, alpha, 20. (95 aa)
Defa25Alpha-defensin 25; May have microbicidal activities; Belongs to the alpha-defensin family. (92 aa)
Defa28Defensin, alpha, 28. (94 aa)
Defa29Alpha-defensin-related sequence 1; Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats. Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins. It may have microbicidal activities; Belongs to the alpha-defensin family. (116 aa)
Defa5Alpha-defensin 5. (93 aa)
Defa3Defensin, alpha, 3. (93 aa)
Defa40Defensin, alpha, 40. (93 aa)
Defa31Alpha-defensin 23; May have microbicidal activities; Belongs to the alpha-defensin family. (93 aa)
Defa22Alpha-defensin 22. (93 aa)
Defa30Defensin, alpha, 30. (93 aa)
Defa23Defensin, alpha, 23. (93 aa)
Defa43Defensin, alpha, 42. (116 aa)
Defa41Defensin, alpha, 41. (93 aa)
AY761185cDNA sequence AY761185. (94 aa)
Mptx2Pentaxin. (219 aa)
Defa27Defensin, alpha, 27. (93 aa)
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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