(10 nodes) Mixed, incl. Limb expression 1, and Long-chain acyl-CoA hydrolase activity network (Mus musculus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

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Your Input:
	Cinp	Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling (By similarity). (212 aa)
	Tmco5b	Transmembrane and coiled-coil domain-containing protein 5B. (307 aa)
	Rubcnl	Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex (By similarity). Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes (By similarity). Bin [...] (675 aa)
	Calhm2	Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family. (323 aa)
	Lingo3	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3. (589 aa)
	6030458C11Rik	UPF0489 protein C5orf22 homolog. (442 aa)
	Acot11	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway. (614 aa)
	Lix1	Protein limb expression 1 homolog; Belongs to the LIX1 family. (282 aa)
	Slco1a5	Solute carrier organic anion transporter family member 1A5; Mediates the Na(+)-independent transport of organic anions such as taurocholate and thyroid hormones; Belongs to the organo anion transporter (TC 2.A.60) family. (670 aa)
	9930104L06Rik	Uncharacterized protein C1orf109 homolog. (217 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
6030458C11Rik	9930104L06Rik	ENSMUSP00000055656	ENSMUSP00000154851	UPF0489 protein C5orf22 homolog.	Uncharacterized protein C1orf109 homolog.	0.494
6030458C11Rik	Rubcnl	ENSMUSP00000055656	ENSMUSP00000045566	UPF0489 protein C5orf22 homolog.	Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex (By similarity). Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes (By similarity). Bin [...]	0.469
6030458C11Rik	Tmco5b	ENSMUSP00000055656	ENSMUSP00000042247	UPF0489 protein C5orf22 homolog.	Transmembrane and coiled-coil domain-containing protein 5B.	0.481
9930104L06Rik	6030458C11Rik	ENSMUSP00000154851	ENSMUSP00000055656	Uncharacterized protein C1orf109 homolog.	UPF0489 protein C5orf22 homolog.	0.494
9930104L06Rik	Acot11	ENSMUSP00000154851	ENSMUSP00000069636	Uncharacterized protein C1orf109 homolog.	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	0.629
9930104L06Rik	Calhm2	ENSMUSP00000154851	ENSMUSP00000047278	Uncharacterized protein C1orf109 homolog.	Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.	0.600
9930104L06Rik	Cinp	ENSMUSP00000154851	ENSMUSP00000035245	Uncharacterized protein C1orf109 homolog.	Cyclin-dependent kinase 2-interacting protein; Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling (By similarity).	0.833
9930104L06Rik	Lingo3	ENSMUSP00000154851	ENSMUSP00000054960	Uncharacterized protein C1orf109 homolog.	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3.	0.502
9930104L06Rik	Lix1	ENSMUSP00000154851	ENSMUSP00000111239	Uncharacterized protein C1orf109 homolog.	Protein limb expression 1 homolog; Belongs to the LIX1 family.	0.766
9930104L06Rik	Rubcnl	ENSMUSP00000154851	ENSMUSP00000045566	Uncharacterized protein C1orf109 homolog.	Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex (By similarity). Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes (By similarity). Bin [...]	0.766
9930104L06Rik	Slco1a5	ENSMUSP00000154851	ENSMUSP00000137607	Uncharacterized protein C1orf109 homolog.	Solute carrier organic anion transporter family member 1A5; Mediates the Na(+)-independent transport of organic anions such as taurocholate and thyroid hormones; Belongs to the organo anion transporter (TC 2.A.60) family.	0.475
9930104L06Rik	Tmco5b	ENSMUSP00000154851	ENSMUSP00000042247	Uncharacterized protein C1orf109 homolog.	Transmembrane and coiled-coil domain-containing protein 5B.	0.766
Acot11	9930104L06Rik	ENSMUSP00000069636	ENSMUSP00000154851	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Uncharacterized protein C1orf109 homolog.	0.629
Acot11	Calhm2	ENSMUSP00000069636	ENSMUSP00000047278	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.	0.450
Acot11	Lix1	ENSMUSP00000069636	ENSMUSP00000111239	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Protein limb expression 1 homolog; Belongs to the LIX1 family.	0.629
Acot11	Rubcnl	ENSMUSP00000069636	ENSMUSP00000045566	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex (By similarity). Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes (By similarity). Bin [...]	0.629
Acot11	Slco1a5	ENSMUSP00000069636	ENSMUSP00000137607	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Solute carrier organic anion transporter family member 1A5; Mediates the Na(+)-independent transport of organic anions such as taurocholate and thyroid hormones; Belongs to the organo anion transporter (TC 2.A.60) family.	0.498
Acot11	Tmco5b	ENSMUSP00000069636	ENSMUSP00000042247	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	Transmembrane and coiled-coil domain-containing protein 5B.	0.629
Calhm2	9930104L06Rik	ENSMUSP00000047278	ENSMUSP00000154851	Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.	Uncharacterized protein C1orf109 homolog.	0.600
Calhm2	Acot11	ENSMUSP00000047278	ENSMUSP00000069636	Calcium homeostasis modulator protein 2; Pore-forming subunit of a voltage-gated ion channel. Belongs to the CALHM family.	Acyl-coenzyme A thioesterase 11; Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.	0.450