(6 nodes) Homeobox protein Hox-A1/B1/D1, and PBX, PBC domain network (Mus musculus)

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Your Input:
	Meis3	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1. (378 aa)
	Hoxb1	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. (297 aa)
	Pbx2	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity). (430 aa)
	Hoxd1	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. (328 aa)
	Pbx4	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family. (378 aa)
	Pknox1	Homeobox protein PKNOX1; Activates transcription in the presence of PBX1A and HOXA1. Belongs to the TALE/MEIS homeobox family. (436 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hoxb1	Hoxd1	ENSMUSP00000019117	ENSMUSP00000043078	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.932
Hoxb1	Meis3	ENSMUSP00000019117	ENSMUSP00000002495	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.	0.458
Hoxb1	Pbx2	ENSMUSP00000019117	ENSMUSP00000040464	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	0.692
Hoxb1	Pbx4	ENSMUSP00000019117	ENSMUSP00000080219	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	0.721
Hoxb1	Pknox1	ENSMUSP00000019117	ENSMUSP00000094966	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Homeobox protein PKNOX1; Activates transcription in the presence of PBX1A and HOXA1. Belongs to the TALE/MEIS homeobox family.	0.914
Hoxd1	Hoxb1	ENSMUSP00000043078	ENSMUSP00000019117	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.932
Hoxd1	Pbx2	ENSMUSP00000043078	ENSMUSP00000040464	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	0.435
Hoxd1	Pbx4	ENSMUSP00000043078	ENSMUSP00000080219	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	0.456
Meis3	Hoxb1	ENSMUSP00000002495	ENSMUSP00000019117	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.458
Meis3	Pbx2	ENSMUSP00000002495	ENSMUSP00000040464	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	0.526
Meis3	Pbx4	ENSMUSP00000002495	ENSMUSP00000080219	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	0.742
Pbx2	Hoxb1	ENSMUSP00000040464	ENSMUSP00000019117	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.692
Pbx2	Hoxd1	ENSMUSP00000040464	ENSMUSP00000043078	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.435
Pbx2	Meis3	ENSMUSP00000040464	ENSMUSP00000002495	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.	0.526
Pbx2	Pbx4	ENSMUSP00000040464	ENSMUSP00000080219	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	0.430
Pbx2	Pknox1	ENSMUSP00000040464	ENSMUSP00000094966	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	Homeobox protein PKNOX1; Activates transcription in the presence of PBX1A and HOXA1. Belongs to the TALE/MEIS homeobox family.	0.873
Pbx4	Hoxb1	ENSMUSP00000080219	ENSMUSP00000019117	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.721
Pbx4	Hoxd1	ENSMUSP00000080219	ENSMUSP00000043078	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	Homeobox protein Hox-D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.	0.456
Pbx4	Meis3	ENSMUSP00000080219	ENSMUSP00000002495	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	Homeobox protein Meis3; Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.	0.742
Pbx4	Pbx2	ENSMUSP00000080219	ENSMUSP00000040464	Pre-B-cell leukemia transcription factor 4; Belongs to the TALE/PBX homeobox family.	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1 (By similarity).	0.430