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| Stx11 | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. (287 aa) | ||||
| Stx19 | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). (292 aa) | ||||
| Unc13d | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. (1083 aa) | ||||
| Lyst | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. (3787 aa) | ||||
| Stxbp2 | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). (593 aa) | ||||
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lyst | Stx11 | ENSMUSP00000106188 | ENSMUSP00000046243 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | 0.764 |
| Lyst | Stx19 | ENSMUSP00000106188 | ENSMUSP00000055901 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | 0.662 |
| Lyst | Stxbp2 | ENSMUSP00000106188 | ENSMUSP00000125405 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | 0.723 |
| Lyst | Unc13d | ENSMUSP00000106188 | ENSMUSP00000074549 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | 0.785 |
| Stx11 | Lyst | ENSMUSP00000046243 | ENSMUSP00000106188 | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | 0.764 |
| Stx11 | Stx19 | ENSMUSP00000046243 | ENSMUSP00000055901 | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | 0.903 |
| Stx11 | Stxbp2 | ENSMUSP00000046243 | ENSMUSP00000125405 | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | 0.982 |
| Stx11 | Unc13d | ENSMUSP00000046243 | ENSMUSP00000074549 | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | 0.947 |
| Stx19 | Lyst | ENSMUSP00000055901 | ENSMUSP00000106188 | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | 0.662 |
| Stx19 | Stx11 | ENSMUSP00000055901 | ENSMUSP00000046243 | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | 0.903 |
| Stx19 | Stxbp2 | ENSMUSP00000055901 | ENSMUSP00000125405 | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | 0.960 |
| Stx19 | Unc13d | ENSMUSP00000055901 | ENSMUSP00000074549 | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | 0.877 |
| Stxbp2 | Lyst | ENSMUSP00000125405 | ENSMUSP00000106188 | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | 0.723 |
| Stxbp2 | Stx11 | ENSMUSP00000125405 | ENSMUSP00000046243 | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | 0.982 |
| Stxbp2 | Stx19 | ENSMUSP00000125405 | ENSMUSP00000055901 | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | 0.960 |
| Stxbp2 | Unc13d | ENSMUSP00000125405 | ENSMUSP00000074549 | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | 0.900 |
| Unc13d | Lyst | ENSMUSP00000074549 | ENSMUSP00000106188 | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. | 0.785 |
| Unc13d | Stx11 | ENSMUSP00000074549 | ENSMUSP00000046243 | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | Syntaxin-11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. | 0.947 |
| Unc13d | Stx19 | ENSMUSP00000074549 | ENSMUSP00000055901 | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). | 0.877 |
| Unc13d | Stxbp2 | ENSMUSP00000074549 | ENSMUSP00000125405 | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis (By similarity). Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity). | 0.900 |