(5 nodes) Regulation of glutamine transport, and Prolactin receptor signaling network (Mus musculus)

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Your Input:
	Prl5a1	Prolactin-5A1. (230 aa)
	Lep	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...] (167 aa)
	Prl6a1	Prolactin-6A1. (230 aa)
	Prl	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. (228 aa)
	Prlr	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (608 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lep	Prl	ENSMUSP00000067046	ENSMUSP00000105998	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	0.968
Lep	Prl5a1	ENSMUSP00000067046	ENSMUSP00000017208	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	Prolactin-5A1.	0.968
Lep	Prl6a1	ENSMUSP00000067046	ENSMUSP00000089269	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	Prolactin-6A1.	0.968
Lep	Prlr	ENSMUSP00000067046	ENSMUSP00000122219	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.774
Prl	Lep	ENSMUSP00000105998	ENSMUSP00000067046	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	0.968
Prl	Prl5a1	ENSMUSP00000105998	ENSMUSP00000017208	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	Prolactin-5A1.	0.919
Prl	Prl6a1	ENSMUSP00000105998	ENSMUSP00000089269	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	Prolactin-6A1.	0.915
Prl	Prlr	ENSMUSP00000105998	ENSMUSP00000122219	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.999
Prl5a1	Lep	ENSMUSP00000017208	ENSMUSP00000067046	Prolactin-5A1.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	0.968
Prl5a1	Prl	ENSMUSP00000017208	ENSMUSP00000105998	Prolactin-5A1.	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	0.919
Prl5a1	Prl6a1	ENSMUSP00000017208	ENSMUSP00000089269	Prolactin-5A1.	Prolactin-6A1.	0.935
Prl5a1	Prlr	ENSMUSP00000017208	ENSMUSP00000122219	Prolactin-5A1.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.998
Prl6a1	Lep	ENSMUSP00000089269	ENSMUSP00000067046	Prolactin-6A1.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	0.968
Prl6a1	Prl	ENSMUSP00000089269	ENSMUSP00000105998	Prolactin-6A1.	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	0.915
Prl6a1	Prl5a1	ENSMUSP00000089269	ENSMUSP00000017208	Prolactin-6A1.	Prolactin-5A1.	0.935
Prl6a1	Prlr	ENSMUSP00000089269	ENSMUSP00000122219	Prolactin-6A1.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.998
Prlr	Lep	ENSMUSP00000122219	ENSMUSP00000067046	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...]	0.774
Prlr	Prl	ENSMUSP00000122219	ENSMUSP00000105998	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.	0.999
Prlr	Prl5a1	ENSMUSP00000122219	ENSMUSP00000017208	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	Prolactin-5A1.	0.998
Prlr	Prl6a1	ENSMUSP00000122219	ENSMUSP00000089269	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	Prolactin-6A1.	0.998