(7 nodes) Muscle filament sliding network (Mus musculus)

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Your Input:
	Tnnt2	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (302 aa)
	Myl6	Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium. (151 aa)
	Myh7	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
	Tpm1	Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. (284 aa)
	Myh6	Myosin-6; Muscle contraction. (1938 aa)
	Myl6b	Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium. (207 aa)
	Myh8	Myosin-8; Muscle contraction. (1937 aa)

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Myh6	Myh7	ENSMUSP00000080538	ENSMUSP00000126840	Myosin-6; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.933
Myh6	Myh8	ENSMUSP00000080538	ENSMUSP00000019625	Myosin-6; Muscle contraction.	Myosin-8; Muscle contraction.	0.563
Myh6	Myl6	ENSMUSP00000080538	ENSMUSP00000128803	Myosin-6; Muscle contraction.	Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium.	0.808
Myh6	Myl6b	ENSMUSP00000080538	ENSMUSP00000026428	Myosin-6; Muscle contraction.	Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium.	0.724
Myh6	Tnnt2	ENSMUSP00000080538	ENSMUSP00000140941	Myosin-6; Muscle contraction.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.965
Myh6	Tpm1	ENSMUSP00000080538	ENSMUSP00000109337	Myosin-6; Muscle contraction.	Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.	0.862
Myh7	Myh6	ENSMUSP00000126840	ENSMUSP00000080538	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-6; Muscle contraction.	0.933
Myh7	Myh8	ENSMUSP00000126840	ENSMUSP00000019625	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-8; Muscle contraction.	0.683
Myh7	Myl6	ENSMUSP00000126840	ENSMUSP00000128803	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium.	0.820
Myh7	Myl6b	ENSMUSP00000126840	ENSMUSP00000026428	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium.	0.801
Myh7	Tnnt2	ENSMUSP00000126840	ENSMUSP00000140941	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.902
Myh7	Tpm1	ENSMUSP00000126840	ENSMUSP00000109337	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.	0.812
Myh8	Myh6	ENSMUSP00000019625	ENSMUSP00000080538	Myosin-8; Muscle contraction.	Myosin-6; Muscle contraction.	0.563
Myh8	Myh7	ENSMUSP00000019625	ENSMUSP00000126840	Myosin-8; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.683
Myh8	Myl6	ENSMUSP00000019625	ENSMUSP00000128803	Myosin-8; Muscle contraction.	Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium.	0.779
Myh8	Myl6b	ENSMUSP00000019625	ENSMUSP00000026428	Myosin-8; Muscle contraction.	Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium.	0.813
Myh8	Tnnt2	ENSMUSP00000019625	ENSMUSP00000140941	Myosin-8; Muscle contraction.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.760
Myh8	Tpm1	ENSMUSP00000019625	ENSMUSP00000109337	Myosin-8; Muscle contraction.	Tropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.	0.749
Myl6	Myh6	ENSMUSP00000128803	ENSMUSP00000080538	Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium.	Myosin-6; Muscle contraction.	0.808
Myl6	Myh7	ENSMUSP00000128803	ENSMUSP00000126840	Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.820